S6.12.2 - After the Semaglutide Approval: Expanding MASH Awareness Will Change Medical Practices

S6.12.2 - After the Semaglutide Approval: Expanding MASH Awareness Will Change Medical Practices

Send us a text Key Opinion Leaders Manal Abdelmalek, Naim Alkhouri, Scott Isaacs and Zobair Younossi join Roger Green to discuss the FDA's approval of semaglutide for patients with non-cirrhotic MASH. This conversation focuses on how the US healthcare system must adapt to handle the growing number of MASH and MASLD patients who might seek treatment, given likely increases in publicity and education. The conversation starts with a focus on the implications of semaglutide approval for hepatolog...

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Day Three of TLMdX 2020 - Sunday at The Digital Liver Meeting -- The Future Looks Bright! - Ep 36

Day Three of TLMdX 2020 - Sunday at The Digital Liver Meeting -- The Future Looks Bright! - Ep 36

Send us a text Reviews of Phase 2 drug trials and diagnostic strategies reveal that NASH is close to multiple breakthroughs. Naim Alkhouri and Mazen Noureddin join Louise and Roger to review highlights from Sunday at The Digital Liver Meeting. Naim, Mazen and Roger review results from drug trials that reveal that multiple drugs (monotherapies and combinations) with potent effects on liver fat reduction and fibrosis are moving through the pipeline. Louise discusses a trial that relies on non-...

16 Nov 20201h 10min

Day Two of TLMdX 2020 - Lean NASH, exciting Diagnostics and Patient-Reported Outcomes as an Endpoint - Ep 35

Day Two of TLMdX 2020 - Lean NASH, exciting Diagnostics and Patient-Reported Outcomes as an Endpoint - Ep 35

Send us a text Manal Abdelmalek joins the Surfers to review some of Saturday's most exciting presentations and posters from AASLD 2020, followed by a discussion of an exciting new hand-held diagnostic. Manal Abdelmalek joins the Surfers in a free-flowing discussion of Saturday's key papers and posters. Much of the talk focused on Lean NASH -- what it is some of the new diagnostic analyses and algorithms used to identify patients with or at risk of the disease. Stephen talked about the extra...

15 Nov 20201h 27min

Why NASH Drug Trials Fail: A Thoughtful, Challenging Theory - Ep 34

Why NASH Drug Trials Fail: A Thoughtful, Challenging Theory - Ep 34

Send us a text Prof. Dr. Jörn M. Schattenberg joins the Surfers to discuss his recent article in Expert Opinion on Investigational Drugs dissecting recent drug trial failures. Prof. Dr. Jörn M. Schattenberg joins Stephen, Donna, Louise and Roger to discuss his recent article "The Nonalcoholic Steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future successes." The discussion started with lessons from failed trials, focusing on the importance of utilizing...

12 Nov 202053min

Previewing The Digital Liver Meeting (TLMDx from AASLD): Part Two - Ep 33

Previewing The Digital Liver Meeting (TLMDx from AASLD): Part Two - Ep 33

Send us a text Stephen Harrison, Roger Green and our guest Surfer, Dr. Manal Abdelmalek, identify pivotally important presentations and posters from The Digital Liver Meeting 2020 SurfingNASH continues our AASLD coverage by asking Stephen Harrison, Roger Green, and guest Surfer Dr. Manal Abdelmalek to identify and review abstracts they consider important or uniquely interesting. The abstracts they chose focus on exciting new agents, the emerging role of #artificialintelligence (AI) and machi...

5 Nov 202056min

Previewing The Digital Liver Meeting (TLMDx from AASLD): Part One - Ep 32

Previewing The Digital Liver Meeting (TLMDx from AASLD): Part One - Ep 32

Send us a text Louise Campbell, Donna Cryer, and Naim Alkhouri identify pivotally important presentations and posters from The Digital Liver Meeting 2020. SurfingNASH kicks off its AASLD coverage by announcing four of our seven KOL guest Surfers. One of them, Dr. Naim Alkhouri, participates via interview. Naim, Louise Campbell, and Donna Cryer identify abstracts they consider important or uniquely interesting. The abstracts they chose focus on population health (particularly juvenile and ped...

29 Okt 202056min

How Have The Events of 2020 Affected Patient Treatment In The Clinic? Ep 31

How Have The Events of 2020 Affected Patient Treatment In The Clinic? Ep 31

Send us a text Guest Surfer and regular listener Dr. Ian Rowe joins the Surfers to discuss how everyday patient treatment in the clinic once was and how COVID-19 and the news we discuss weekly on SurfingNASH have changed practice. This week's Guest Surfer, Dr. Ian Rowe, devotes roughly half his time to treating patients in his Hepatology practice in Leeds, UK, and the other half on research and teaching issues. He joined the Surfers to discuss how patients were referred to his clinic and how...

22 Okt 202056min

Six Months In: How COVID-19 Has Changed Our World!

Six Months In: How COVID-19 Has Changed Our World!

Send us a text On the six-month anniversary of SurfingNASH's first episode, the Surfers stop to consider how much has changed for NASH stakeholders since April Thursday marks the six-month anniversary of SurfingNASH's first episode. The last six months have seen both setbacks and large steps forward in drug development, major advances in disease knowledge and increased breadth and depth of patient advocacy. The Surfers reflect on all these changes while remembering key steps in the podcast's...

15 Okt 202047min

COVID-19 and the Liver, “it's complicated - Ep 29

COVID-19 and the Liver, “it's complicated - Ep 29

Send us a text Matt Kelly, Chief Innovation Officer at Perspectum, Ltd., joins the Surfers to discuss early findings from the COVERSCAN study which looks at the relationship between COVID-19 infection and major end-organ systems. Matt Kelly, Chief Innovation Officer at Perspectum, Ltd. joins the Surfers to discuss two studies that look at the relationship between COVID-19 and the liver. In the COVERSCAN study, Perspectum plans to conduct multi-organ scans of 500 patients who have recovered f...

8 Okt 202054min

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