The Dr Louise Newson Podcast2 Sep 2025

23 - The truth about GLP-1s, weight loss and nutrition with Dr Jack Mosley

GLP-1 medications such as Ozempic, Wegovy and Mounjaro have become some of the most widely discussed weight loss treatments in the world. They were once mainly talked about in medical research, but now they’re a regular feature in celebrity culture, weight loss headlines and even major advertising campaigns, including one recently fronted by Serena Williams.

But beyond the endorsements and headlines, what do we really know about these drugs? How effective are GLP-1 weight loss medications, what risks and side effects should be considered, and how should they fit alongside approaches like nutrition, exercise and hormone balance?

In this episode, Dr Louise Newson is joined by Dr Jack Mosley, GP registrar, author and son of the late Dr Michael Mosley. They explore the science, benefits and limitations of GLP-1s, why weight management remains such a challenge, and how lifestyle and medical treatments can complement one another.

Jack also reflects on his father’s legacy and offers his own perspective on where medicine is heading. It’s a thoughtful and wide-ranging discussion that brings clarity to one of the most high-profile debates in health today.

Don’t forget, the Dr Louise Newson Podcast has been nominated in the British Podcast Awards. You can vote here: https://www.britishpodcastawards.com/voting

Available to watch on YouTube

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