Cellular Senescence, Why the Goldilocks Approach is the ONLY way to go and SELANK: more than just another brain peptide
Dr. Seeds is a board-certified orthopedic surgeon and physician specializing in all aspects of sports medicine and total joint treatments. With over 22 years of experience, Dr. Seeds is focused on providing the most innovative results to those seeking to maximize their performance, relieve injuries, and live a healthy lifestyle. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
2 Nov 20201h 2min
Repair Peptides: TB500 vs Thymosin Beta 4, they are NOT the same
Thymosin Beta 4 and TB500 - are they one and the same? NO! We are BACK!!! In the peptide world these two peptides are often referred to interchangeably....as if they were one. And yet - they are most certainly not! In this short interview Jean-Francois Tremblay from CanLabs explains how they are related but quite different and how they may work together in certain scenarios. Remember - none of this information is to be used as medical advice ...there is a LOT we do not know about peptides hence peptides are still rated as "research chemicals" so before you even think of using these please consult with a medical professional to assess any risks. 5:00 Amino acids 17-23 6:30 Anti-fibrotic 7:00 Why people interchange TB500 and Thymosin Beta 4 9:00 If you want a tan just take melanotan2 9:10 For sensory effect take this peptide 9:30 If you want more take this peptide 9:50 "Moron proof" peptides 12:30 Neuro benefits of Thymosin Beta 4 14:15 Used for race horses 15:20 Number of peptides in Thymosin Beta 4 chain. 15:45 How to double names and peptides: the number 23:00 The of peptides 23:50 Cost effective 26:00 TB4 pills and the issue of digesting 27:30 How peptides digested work with leaky gut better in the beginning 31:40 BPC-157 is an orally available peptide 32:40 TB500 hones in on musculoskeletal system https://www.canlabresearch.com/ Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
29 Okt 202034min
Find Out How Fast (or Slowly) You're Aging with Épi-Age & Dr Moshe Szyf
Dr. Szyf is a pioneer in the field of epigenetics, he holds a PhD from the celebrated Hebrew University, a postdoctoral fellowship in Genetics at Harvard Medical School, a Professorship at McGill University and a Chair in Pharmacology at GlaxoSmithKline. 5:33 DNA as the operating system of our lives 6:14 Disease causes disruption in the DNA 6:41 DNA methylation gives us an insight into what's going on in our DNA 7:07 Epi Age testing can tell us how many years we've been living in this world, and may give insight into how many years we may have left 8:02 Chronological age and epigenetic age can be good indicators for life span 11:17 Epi Age is a lifestyle product 12:59 Identifying the markers for aging 14:23 How Epi Age is different 17:05 What are the most effective ways to slow down the clock? 17:29 Behaviours that can help slow down the clock 18:28 epiAging app 19:51 epiAge test results tell you what you're DNA thinks of what you're doing 22:21 The first step in slowing down the clock is to get to a state of balance 23:58 Using AI to derive some conclusions from an individual result against a general lifestyle model 24:30 The great revolution will come from mathematics and technology to capture the complexity of humans 26:24 The idea of sharing -- creating a "Waze" of health 27:08 Health data safety and privacy 28:06 Balancing privacy and sharing -- learning about diseases without consequences to the individual 29:00 Sharing public methylation data can help save millions of lives 31:19 Firewalled personal data and medical data -a solution to protect the individual 32:25 Goal: To get the best solutions to prevent anyone to hack the database 33:41 The collaboration between Epi-Age and users 36:41 The best way to use the Epi-Age test 40:25 Transferring the responsibility of health from your doctor to yourself 40:45 Experience as a teacher 41:10 Trial, error, and scientific truth 41:36 Self-empowerment and the biohacking movement 43:22 Technology empowers people about medicine 44:37 epiAge app as a source of information for lifestyle trends 48:11 Environmental influence on genetics 49:38 The impact of your mental environment on your health 50:02 Listen to your own clock Ordering tests: Epi-Age.com Use Promo code Longevity to get 10% off the cost of your test…. Link to Dr Szyf's Ted Talk: https://youtu.be/38OUCtzkT4Q Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
26 Okt 202055min
Dr Amber ND - Peptide Expert - Mitochondrial Peptides for Ultimate Cellular Energy
Dr. Amber is an A4M trained peptide expert and Naturopathic Doctor practicing out of beautiful California. In this episode we talk about two peptides that address mitochondria and why that's an amazing place to start with peptides. Dr. Amber uses the term "forgot" which you'll learn why towards the end of the show, and how to remind your body of proper signaling and why peptides are so amazing! Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes. 1:30 Why we start with MITOCHONDRIA 2:15 Theory of aging 3:15 A4M 5:25 The issue with the thought of "getting energy from energy drinks" you are an energy factory 6:45 Why issues show up in the brain and heart first 9:00 The link between Fibromyalgia and mitochondrial dysfunction 10:00 Inflammation, why it needs to be addressed first so that one can then add things like peptides to help with repair 11:00 How common analgesics (pain relief pills) negatively affect mitochondria 12:30 How blue light negatively affects melatonin production 13:10 Things that damage the mitochondria. 13:20 How to create new mitochondria 13:45 Why sleep is so important 15:00 Ways to mitigate damage, there are amazing things you can do :) 15:20 Computer software to reduce blue light and protect your eyes and mitochondria 16:30 Offset the positive ions with negative ions by going to a natural body of water or grounding 17:00 Red light can upregulate production of ATP and mitochondria 19:30 Cold water exposure 21:30 Why Nathalie likes cold lakes over a tub 😂 22:15 Our cells make waste naturally, not including environmental factors, that's normal. This is why we need to support detoxification 23:00 Leveraging hormetic stressors. LDN and adaptation principle to your benefit. 23:40 Molecular hydrogen, because we need oxidation, but this works almost like an adaptogen 24:45 HIIT workouts for the win! 25:00 Cell senescence 27:00 SS31 28:20 May be useful for - cardiac issues, insulin/pancreatic dysfunction, depression, fibromyalgia, chronic fatigue, anti-aging. 30:15 Amount needed of SS31. 33:00 Our bodies make these peptides, but often "need instructions" or a reminder... 34:30 How the wrong peptide at the wrong time can do more harm than good, and the right peptide at the right time can really do wonders and promote signaling that the body really needed and "forgot" about. 37:00 Melanotan 39:00 Nutrition is incredibly important, but here's why you often need help from peptides 40:10 5-Amino-1MQ (capsule, no needle use) 41:50 How 5-Amino-1MQ keeps your NAD around longer 42:50 L-carnitine 43:30 Dosing of 5-Amino-1MQ 44:00 How some people react very different, triggering more anxiety 46:00 Sublingual NAD powder that Nathalie loves 47:10 The placebo of peptides and supplements and the power of belief 48:45 The issue with digesting supplements 49:15 Leaky gut 50:30 NAD The patch versus IV, and why you can get more from the patch! 52:30 Kisspeptin peptide, for men vs. women, "kiss-54" "kiss-10" 55:45 Natural increase of testosterone 56:00 Why Dr. Amber uses the term "forgot"...and how to remind your body of proper signaling 57:00 And why you should avoid exogenous testosterone for as long as possible 57:45 Kiss-54 https://www.instagram.com/doctorambernd/ drambernd.com
16 Okt 20201h 3min
Dr. Elizabeth Yurth Peptide Expert - DSIP Sleep Peptide, Hormones and The Shocking Truth about Melatonin
Dr. Yurth is on the cutting edge helping her clients prevent joint replacement with the use of peptides, hormones and preventative medicine. She's an expert on circadian rhythm and how to fix yours with peptides and other biohacks! Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes. http://boulderlongevity.com/ 3:13 Dr. Yurth Background 12:00 industry is about lifelong learning and questioning what we thought we knew 14:00 Take responsibility for your own 15:00 Why Nathalie and Dr. Yurth would rather spend money on their than a fancy 16:00 How you shouldn't expect a peptide to do ALL of the work for you 19:00 Peptides and your Circadian rhythm and deep and REM sleep. 20:54 The best time to have surgery 22:00 The Clock Gene 22:29 How do we fix the circadian rhythm in you 24:50 How this sleep tracker shows you the impact of your actions 25:50 How to increase deep sleep time "the brain cleanout time" 26:21 If you're frustrated that these biohacks aren't "helping you" 26:10 Sleep quality vs. quantity, and how too much sleep can be bad, and what really matters most 28:55 How DSIP could be better for some people in the morning for sleep that night, and great for some in the evening. 31:50 Muscle building 34:30 The other benefits of melatonin 37:33 Stacking and why you should give something a chance 38:30 Biohacking for night shift workers, must biohack 40:25 Why you should take melatonin, and if you're a slow metabolizer of melatonin listen to this! 46:15 How most disease can be linked back to circadian rhythm 50:39 How being breast fed vs. bottle fed and how timing of feeding affects children 54:30 Neuropathy 56:07 Kidney function 56:24 Fibromyalgia 59:32 Pulsing: turning on, turning off, turning on, turning off 59:55 How long to try a peptide for http://boulderlongevity.com/ https://www.instagram.com/dryurth/
6 Okt 20201h 5min
Hack Light, Mitigate EMF's to Upgrade Your Health with PrimalHacker Thaddeus Owen
Thaddeus Owen the co founder and owner of PrimalHacker has been deep diving into how light and EMF's affect our health and physiology for almost as long as I've known him. He is a wealth of information on the topic and in this episode we deep dive into the many issues impacting our health and, more importantly what we can do about it. For the most part we stick to easy and free interventions you can apply starting today - and we even mention a peptide in our conversation! PrimalHacker sells a curated selection of items that can help you to live a healthier light life including Blue Blockers, Red Lights and more - all at incredibly affordable prices. PLUS you can use Promo Code NAT10 to get an extra 10% off your entire purchase! Please note that this video is for information purposes only and that none of the information in this video is intended as medical advice. Please consult with your health provider before starting any new intervention and especially if you have a medical condition. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.
25 Sep 20201h 5min
Peptides for Fat Loss w/ CanLab: Setmelanotide, AOD 9604, FRAG17691, Tesamorelin, CJC 1295 NO Dac
In this Interview, Jean-Francois Tremblay, owner of CanLab and I dig in to one of the new darlings of the peptide world - Tesamorelin and a less known but possibly just as effective other option - Setmelanotide - an offshoot of the better known Melantonan 2. We also cover AOD 9604, FRAG 17691 and CJC1295 ...and why you probably want to avoid the version with DAC (drug affinity complex)... We start with a chat about how if you're after lasting results there's really no way to avoid optimizing your diet, moving more, optimizing sleep etc... but these peptides might just help to speed things along and ease some of the bumps along the way. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes. Show Notes: Keto Calorie Peptides Help with Fat Loss Body Recomposition Growth Hormone unregulated by Fat Loss peptides like FRAG 17691 or AOD9604 (just one amino acid difference) help to mobilize fatty acids in the fat cell – but need to be in calorie/energy deficit for it to stay out Consistency and sticking to your plan is the ultimate secret sauce… Why Canlab combines Frag and AOD 9604 More about Frag and AOD….are they the same or different? AOD lacks one tyrosine…means that it lasts longer…whereas Frag uses more up front and gets metabolized faster….. Tesamorelin…..what it does…. The skinny on Tesamorelin….it's not about Tesa it's about the growth hormone release…. Re Muscle Gains attributed to Peptides….in studies re old people it's about bringing back muscle you once had…. Hormone replacement therapy is at the foundation of reclaiming muscle mass GH good for muscle sustaining (vs growth) and tissue repair (but doesn't hold a candle to BPC and TB4) Tesamorelin – origins – where it came from originally….very close to CJC 1295 (Mod IGRF 121 is actually CJC 1295 without dac). and other Growth Hormone Secretagogues. The difference between Tesa and CJC not really all that great….why some people may be promoting Tesa over CJC 1295 the magic is in the dose. Difference about with Dac and without Dac. With Dac too many peaks of growth hormone (similar to MK 677….increases risk of insulin resistance…..why is the Dac long lasting…binds to albumin in the blood ….which is problematic as there may have been relationship to blood cancer seen in certain studies….so better to use without DAC…just use multiple times a day if necessary Post workout (3) is a good time…but pre bed(1), pre workout and first thing in the morning (2) are all better Setmelanotide – another derivative of alpha MSH (Melanotan, melanotan 2, PT141) Basically prioritizes appetite suppression over tanning and sexual enhancement..they all create a tan just to varying degrees…. SM get appetite curbing (some sexual stim)…increases metabolic rate by about 6%, without increasing HR or BP…. On average can expect about 1 lb a week fat loss…. Many reports of people using it with good results – safe track record…..Clinical studies went for 12 months Do not start at full dose of 1.5mg a day….start at .5 1-2 days then 1.0mg for a couple of days and then increase to full dose to avoid possible /nausea In studies – they changed nothing else….and saw results but it's likely that as people lost weight they may have started to move more etc… At this point best method for most peptides is SubQ over oral….Intranasal may work but need to use higher dose (aka PT141 1 mg is SubQ and 2mg is IntraNasal) Tesofensine – not a peptide acts on dopamine and AC receptors in the brain so needs to be used with great caution Please note that this video is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition.
25 Sep 202052min
