Episode #214: A Deep Dive into Stem Cells and Exosomes (+ How to Stimulate Them without Therapy) with Dr. Amy Killen

Episode #214: A Deep Dive into Stem Cells and Exosomes (+ How to Stimulate Them without Therapy) with Dr. Amy Killen

In this episode of Biohacking Superhuman Performance with guest Dr. Amy Killen, we explore the world of stem cells - what they are, how they perform in the body, and how they work to increase longevity. Stem cell therapy is still being researched and regulated, but there is an amazing amount of potential for healing and increasing longevity with these powerful cells.

We also dive into exosomes - the small molecules that can penetrate places that stem cells can't. Aesthetic procedures are popular with exosomes- they have the power to restore hair and rejuvenate skin, and are used in many skincare products. We even go over ovarian rejuvenation and Rapamycin, a potential prescription drug for delaying menopause.

Overall, this episode offers guidance on stimulating stem cells right in your own home. We talk through different tips such as supplements, fasting, and getting sun in a healthy way for those who aren't in a place to budget for stem cell therapy.

Dr. Amy Killen is an outspoken advocate for empowering people to look and feel their best by merging lifestyle modification, integrative medicine, body-identical hormones, energy modalities, and stem cell therapies. She is the founder and CEO of the Human Optimization Project (HOP), a longevity-based subscription supplement company that stays on top of the science and constantly updates its ingredients for customers who can't devote their lives to reading the latest research sourcing the best therapies. I absolutely love her Instagram. You guys need to go follow her @dr.amybkillen.

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Thank you to our sponsors for making this episode possible:

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Find more from Dr. Amy B. Killen:

Website: https://dramykillen.com/

Youtube: https://www.youtube.com/channel/UCBLk8xTa4qzE7J8bID7KIKg

Instagram: @dr.amybkillen

Human Optimization Project (HOP box): https://hopbox.life/

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ

Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

Instagram: https://www.instagram.com/nathalieniddam/

Website: https://www.NatNiddam.com

Join Nat's Membership Community: https://www.natniddam.com/bsp-community

Work with Nat: Book Your 20 Minute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08

What We Discuss:

(1:30) Women's unfounded fear around Hormone Replacement Therapy

(5:38) When you start hormones early you reduce the risk of major women-killing diseases such as heart disease and obesity.

(7:20) The world of stem cells and exosomes- what they are, and why they are important.

(11:20) MSC cells are very safe, don't cause cancer, and they're not embryonic cells (no fetus is harmed!)

(13:50) The Pros of using birth product stem cells (from the placenta and umbilical cord)

(18:08) The environment where the stem cells are placed matters.

(22:50) Helpful therapies to stack with stem cell therapy.

(30:50) What the research shows about stem cell therapy and diseases like MS.

(34:15) Exosomes - one of the signaling molecules of stem cells. i

(41:37) Fat transfers are a great natural filler, but adding stem cells creates better results.

(44:50) How to stimulate stem cells naturally if you don't have the budget for stem cell therapy.

(58:30) The overuse of supplements and HOP box.

(1:04:00) Rapamycin and ovarian rejuvenation using stem cells.

(1:10:38) Where to find more from Dr. Amy B Killen.

Key Takeaways:

  • 1. Stem cells do two main things. They can replicate themselves and they can turn into other types of cells. Stem cells send out signals so that an injured area heals itself. When we age, we have fewer, less active stem cells. They aren't able to signal repair as well, so recovery takes much longer. Stem cell therapy gives you back signaling molecules so that you're able to heal yourself faster.
    Autologous stem cells are your own cells from fat tissue or bone marrow.
    Allogeneic stem cells come from somewhere else - like birth tissue products (placenta/umbilical cord).
  • The environment affects the stem cells. The area where you put stem cells matters, and if your body is not healthy, is inflamed, or has uncontrolled blood sugar issues, the cells cannot work as well. For example: a smoker or poorly controlled diabetic won't have the best results. Take the time to get in the best shape that you can before a costly procedure like stem cell therapy.
  • Exosomes are powerful signaling molecules that can be transported into cells to change the behavior of that cell. These small molecules can pass through the skin- they can be applied topically - and they can cross the blood brain barrier to decrease inflammation. They're great for aesthetic purposes like hair restoration and skin rejuvenation. The FDA regulates the application - they can only be applied topically.
  • Bonus takeaway: No drug can do what hormones do when used properly at the right time in the right way. If you want to be healthy for longer, especially after menopause, you need to be looking into HRT.

Avsnitt(383)

BioHack with Breath Work - One Hour with JP Crimi = 20 Years of Therapy. How This Unique Style of Breath Work Can literally Transform Your Life & Your Health

BioHack with Breath Work - One Hour with JP Crimi = 20 Years of Therapy. How This Unique Style of Breath Work Can literally Transform Your Life & Your Health

Breath Work with JP Crimi This episode could possibly change your life in as little as one hour for less money than you spend in an average week on coffee. Breath work is nothing new but I can promise you that you've never experienced it quite like this before. Jon Paul Crimi has developed a technique that he delivers live online every Sunday to people from all over the world - you owe it to yourself to try it just once. In this episode you'll get a taste of JP and what breath work might just help you to access in yourself...check it out, sign up for a class and then send me a note to share your experience - I guarantee that you won't regret it!! Enjoy!! 01:18 Introduction to John Paul Crimi - from Boston to LA Sobriety Coach to the Stars to today 6:18 the autoimmune condition that ended JP's acting career and launched him on the journey that led to where he is today… 13:13 How a Stanley cup Final Hockey Game in 2012 with Matthew Perry led to an audience with Tony Robbins...the next step 17:07 Conscious Connected or Circular Breathing what it is and how JP came to develop his own style... 21:54 The benefits of Live online classes vs Live classes 23:04 What is it about crying that is so essential for your health 24:14 HOW Breathwork clears the way for transformation in every part of your life differently than therapy 27:21 Turning off your inner critic 29:56 Breathwork as a gateway to meditation... 33:25 Using breathwork to help resolve physical issues 35:49 The difference of JP's breathwork classes - the power of the right music and a coach who pushes you to your limits… 39:00 JP's deal with the universe and ultimate goal… 43:56 Becoming a Breath Work teacher…. To try a class for yourself: https://www.breathewithjp. On Instagram: @jonpaulcrimi

10 Dec 202051min

Love Your Liver Episode: Bioregulators and peptides to support the Liver with Jean-Francois Tremblay from CanLab Research

Love Your Liver Episode: Bioregulators and peptides to support the Liver with Jean-Francois Tremblay from CanLab Research

In this episode Jean-Francois Tremblay returns for a deep dive into Liver health. Too often the liver is our forgotten hero. Your liver is responsible for detoxifying hormones, toxins, processing fats, making cholesterol, storing energy and so much more….and all to often we abuse it and leave it struggling under an overwhelming burden until it just can't cope anymore - it fills with fat, gets slow and sluggish, cholesterol and triglycerides build in the blood stream, toxins go unchallenged and chronic preventable diseases start to take hold. Join us to talk about ways to support your liver and how bioregulators and peptides may be part of the solution. Some of the topics we cover: ● 01:32 What is non-alcoholic fatty liver disease? ● How the Bioregulator Livagen and CanLabs' new Peptide Combo (LRP, LQP, GPETAFLR) may help treat non-alcoholic fatty liver disease ● Differentiating between therapeutic (treating an existing problem) and preventative use of peptides and bioregulators ● The concept that "Therapy is not the peptide, the peptide is part of the therapy". ● Fatty liver peptide research ● How long it could take to see results…. ● Assessing the quality of your peptides ● Using HPLC to measure peptide purity ● Precautions on peptide purity Disclaimer: Canlabresearch.com (promo code Niddam10 for 10% off anything in the store) Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

8 Dec 202056min

The Antioxidant Myth, Losing Fat and Building Muscle with Novel Peptides with Dr. Elizabeth Yurth

The Antioxidant Myth, Losing Fat and Building Muscle with Novel Peptides with Dr. Elizabeth Yurth

Elizabeth Yurth, MD is the Medical Director of the Boulder Longevity Institute which she co-founded in 2006. The Boulder Longevity Institute specializes in advanced, research-based longevity medicine including treatments such as Bioidentical Hormone Replacement Therapy and Regenerative Peptide Therapy. Dr. Yurth is double board-certified in Physical Medicine & Rehabilitation and Anti- Aging/Regenerative Medicine. As a specialist in Sports, Spine, and Regenerative Medicine, Dr. Yurth has a Stanford-affiliated Fellowship in Sports and Spine Medicine, and a dual-Fellowship in Anti-Aging and Regenerative Medicine (FAARM) and Anti-Aging, Regenerative and Functional Medicine (FAARFM) through the American Academy of Anti-Aging Medicine (A4M). Dr. Yurth has been selected as one of the 25 mastermind physician fellows in SSRP (Seeds Scientific Research and Performance) which allows her to stay abreast and teach others in the emerging field of cellular medicine. An active herself, Dr. Yurth has consulted with numerous sports teams including the 49ers and the Stanford women's and . She has served as a Physician for the / Ballet. Dr. Yurth resides in Boulder, Colorado with her husband and five children. In this episode I sit with Dr Yurth (or Betsy as she prefers to be called) and we talk about the common and yet complex issue of building muscle and losing fat mass. As so many people have discovered this is often nowhere nearly as simple as we think it should be, particularly as people get over the age of 45. We talk about lifestyle, hormones, exercise, and of course - peptides including two peptides that are rarely considered when someone is trying to "lose weight" or, as we prefer to say - improve their body composition. It's a great episode - and if you get value from it, here are ways you can support the podcast - leave a written review on whatever platform you are listening on, share it with your friends and family….and remember that you can connect with me on Facebook or MeWe in the Biohacking Superhuman Performance Group or, if you're interested in working with me or have any comments about the podcast through my website NatNiddam.com. Show Notes: 8:00 Alcohol's negative effects on weight loss & hitting your goals (if you are a committed drinker you may not enjoy this part of the podcast 😉) 10:40 The myth about antioxidants 15:50 SSRP Mastermind - Medical Practitioners coming together on developing Peptide Protocols taking a cellular approach…. 19:40 Identifying obesity and its associations with other diseases 22:00 The link between obesity and inflammation - what comes first? 23:00 Peptides for weight loss - where does Thymosin Alpha 1 fit in? 25:30 Where does Molecular Hydrogen fit in? 28:00 Setmelanotide - for hunger management - strategic use 20:00 MotsC as an exercise mimetic in certain cases... 30:40 The relation of growth hormone levels, weight loss, and ageing 32:00 Growth hormone secretagogues for weight loss - Tesamorelin, CJC/Ipamorelin 34:20 How long workouts may be working against you if you're trying to lose weight 36:00 Figuring out your eating window 41:11 Digestion and digestive enzymes 43:08 AOD 9604 - does it work? Relation of dosage, effectivity, and cost for fat loss peptides 44:28 Oxytocin for fat loss, increasing lean mass and bone production 48:00 How to use oxytocin based on desired result – nasal spray vs injection vs injection 01:02 Ketone Esters for fat loss by reducing inflammation 01:06 Exercise for Fat Loss - weight lifting, bands, Hiit, Body weight exercises instead of long duration cardio To connect with Dr Elizabeth Yurth - http://boulderlongevity.com To connect with Nathalie - https://www.natniddam.com Join Us on MeWe in the Biohacking Superhuman Performance Group: https://mewe.com/group/5d59c5d80264794bb98d124b Or on Facebook: https://www.facebook.com/groups/462749384302295 Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

2 Dec 20201h 15min

A portable AND affordable Red Light & Near Infra Red Light device that can help to heal your injuries, improve your skin, improve your immunity, your gut health and more…Dr Zulia Frost shares all on the new FlexBEAM…

A portable AND affordable Red Light & Near Infra Red Light device that can help to heal your injuries, improve your skin, improve your immunity, your gut health and more…Dr Zulia Frost shares all on the new FlexBEAM…

The FlexBEAM is a tiny and mighty new entry in the photobiomodulation space - the team at Recharge set out to make the safest, most powerful, portable and affordable red light and near infra red light device on the market and it is finally available to you! In this interview I talk to Dr Zulia Frost co founder and co creator of this incredible device and we talk about how to use it and all the things it can do including: Support Immunity Speed up healing of injuries Reduce Pain Support and improve gut health Target specific organs And much much more… Use this link https://bit.ly/FlexBEAM2 and discount code Longevity30 to save $30) Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment.Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

27 Nov 202056min

Dr Amber Part 2 on Mitochondrial Energy: MotsC and NAD

Dr Amber Part 2 on Mitochondrial Energy: MotsC and NAD

Please note that this content  is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment.  Peptides are for the most part classified as research chemicals so should not be used on humans.  Before changing your diet or using any new supplement make sure to consult with your care provider.  Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

25 Nov 202052min

Sleep Crown: The Sleep Hack You've Never Heard of that will Supercharge Your Sleep

Sleep Crown: The Sleep Hack You've Never Heard of that will Supercharge Your Sleep

https://www.natniddam.com/ https://www.sleepcrown.com/ Longevity10 saves you 10% off Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

21 Nov 202043min

Why You Need to Optimize Your Hormones BEFORE anything else with Caleb Greer FNP-C - the best kept secret in functional medicine

Why You Need to Optimize Your Hormones BEFORE anything else with Caleb Greer FNP-C - the best kept secret in functional medicine

In my opinion Caleb Greer is one of the best kept secrets in Functional Medicine. One of his many superpowers is his ability to take the best from the world of conventional medicine and marry it to Functional practice to get his patients the results that they seek. From hormone optimization to peptides, personalized nutrition to the judicious use of pharmaceutical compounds when they are called for - Caleb covers it all - which is why Caleb and I will often collaborate on optimizing clients' results…this podcast is just an intro - stay tuned for more episodes where we dive deep into various topics. For today, we start with hormone optimization. Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

13 Nov 202045min

Deep Dive into Molecular Hydrogen with Alex Tarnava

Deep Dive into Molecular Hydrogen with Alex Tarnava

Alex Tarnava of HRW https://drinkhrw.com/ Promo Code: Longevity10 to get 10% off your purchase 0:11 Alex Tarnava and DrinkHRW 1:06 DrinkHRW aims to get messaging right and put forth an honest and accurate voice 02:52 How Alex Tarnava got into molecular hydrogen 04:09 From fit to sick 08:26 Hydrogen as a viable option to regulate inflammatory response 10:12 Hydrogen Testing 10:56 Getting the right amount of molecular hydrogen 11:15 Cautionary tale about molecular hydrogen products 12:34 What drove Alex to create HRW 15:44 Initial stages for hydrogen tablet 16:49 What it takes to scale production 21:27 Marketing the Hydrogen tablets 21:42 Alex's Ethical requirements: doing good rather than just making money 22:20 Clinical outreach program 22:38 The underlying issue on pharmaceutical and supplemental research 26:14 How much you need to use to dissolve your Hydrogen tablets and why... 28:42 Dissolution kinetics when mixing hydrogen tablets with 29:36 How to get the highest dose of hydrogen 29:59 Hydrogen is most effective during intermittent high dosing Molecular Hydrogen and…. 32:29 Metabolic syndrome 32:49 Multiple research and clinical trials about the benefits 34:12 Rodents, hydrogen treatments, and Parkinson's Disease 39:25 Traumatic Brain Injury 41:02 Oxidative stress, inflammation, insulin sensitivity 44:44 Molecular hydrogen as a selective antioxidant? 46:19 Restoring proper functions in the critical systems in our body and not as a pharmacological agent 47:12 Molecular Hydrogen and Fasting 48:48 The need for better evidence about Fasting in the Biohacking community 51:40 Panacea contributes to the reluctance of researchers to publish studies 52:25 The need for a cultural shift within biohacking and integrative medicine 53:08 There's no toxic dose of molecular hydrogen 55:11 Bath tablets: absorbing hydrogen through the skin 57:43 Why adding lemon to your hydrogen is a good idea beyond taste 58:23 Topical application for molecular hydrogen 59:47 Alex's new project: Myjourney. and biohacking 1:01:36 About wearable technologies 1:06:29 The goal of Myjourney. 1:09:18 Helping researchers explore the best benefits of various biohacks via myjourney. research grants 1:09:56 Data privacy and community collaboration Links: https://drinkhrw.com/ Save 10% off your with promo code: Longevity10 @drinkhrw (Instagram) Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

9 Nov 20201h 15min

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