Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

Antibiotics vs Appendectomy for Uncomplicated Appendicitis Treatment

Appendicitis is one of the most common reasons people undergo abdominal surgery. Lost in history are the reasons why appendectomy was performed in the first place, and in the hundred years since appendicitis was first described, many changes in patient management have occurred improving both the diagnosis and treatments for appendicits. A major trial, Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis, was recently published in JAMA showing that most patients with acute, uncomplicated appendicitis can be treated with antibiotics alone and avoid surgery.

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An Overview of Postural Orthostatic Tachycardia Syndrome (POTS)

An Overview of Postural Orthostatic Tachycardia Syndrome (POTS)

POTS is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. Author Satish Raj, MD, MSCI,...

24 Aug 28min

Medication Treatments for Alcohol Use Disorder

Medication Treatments for Alcohol Use Disorder

Naltrexone, acamprosate, disulfiram, and topiramate are effective but underused medications for treatment of alcohol use disorder. Author Stephen Holt, MD, MS, of Yale School of Medicine joins JAMA De...

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Liquid Biopsy Tests for Cancer

Liquid Biopsy Tests for Cancer

Circulating tumor DNA (ctDNA)(liquid biopsies) can help monitor cancer progression, detect residual cancer after treatment, and identify genetic changes within cancer cells that could affect treatment...

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Patient-Clinician Communication About Physical Activity

Patient-Clinician Communication About Physical Activity

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6 Aug 10min

Classic Hodgkin Lymphoma

Classic Hodgkin Lymphoma

Hodgkin lymphoma is a relatively rare disease, with approximately 82 409 incident cases reported globally in 2022, and 8720 cases reported in the US in 2025. Author Alison Moskowitz, MD, of Memorial S...

3 Aug 20min

The Sleep-Weight Connection

The Sleep-Weight Connection

Suboptimal sleep quality and quantity are associated with higher body mass index and more difficulty losing weight. In this podcast, JAMA Insights author Atul Malhotra, MD, from the University of Cali...

29 Juli 13min

Management of Dyslipidemia

Management of Dyslipidemia

Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of global mortality and is strongly associated with cumulative exposure to atherogenic lipoproteins across the lifespan. Author A...

20 Juli 23min

Hip Fractures: Management and Prevention

Hip Fractures: Management and Prevention

Hip fractures are a leading cause of disability and death in older adults. This episode summarizes  risk factors, prevention, and medical and surgical management of  hip fractures. JAMA Deputy Editor ...

16 Juli 19min

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