#436 — A Crisis of Trust

#436 — A Crisis of Trust

Sam Harris speaks with Michael Osterholm about his new book, The Big One: How We Must Prepare for Future Deadly Pandemics. They discuss the lessons learned from the COVID-19 pandemic, the major mistakes made in the public health response—including lockdowns, school closures, and border policies—the science of airborne versus droplet transmission, the promise and controversy of mRNA vaccines, the reality of vaccine adverse events, the politicization of vaccine hesitancy, and the erosion of scientific institutions like the CDC and HHS under the Trump administration. Looking forward, they explore the characteristics of a future, more deadly pandemic—what Osterholm calls "The Big One"—and what we should be doing to prepare for it.

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Avsnitt(500)

#486 — Luck All the Way Down

#486 — Luck All the Way Down

Sam Harris speaks with Kathryn Paige Harden about behavioral genetics, moral luck, and the problem of blame. They discuss Harden's book Original Sin, the controversy over Charles Murray and Ezra Klein...

22 Juli 0s

#485 — The New Science of Cancer

#485 — The New Science of Cancer

Sam Harris speaks with Siddhartha Mukherjee about the science of cancer. They discuss the updated edition of The Emperor of All Maladies, whether cancer is one disease or many, why prevention is so ha...

14 Juli 1h 21min

#484 — Artificial Intimacy

#484 — Artificial Intimacy

Sam Harris speaks with Paul Bloom about our relationships with AI and the future of human connection. They discuss the surprising pace of AI progress, AI companions as a remedy for loneliness, the imp...

8 Juli 27min

#483 — The Knots We Tie Ourselves Into

#483 — The Knots We Tie Ourselves Into

Sam Harris speaks with Alain de Botton about the psychology of unhappiness, the secular world's discomfort with ecstasy and ritual, psychedelics as a tool for self-discovery, Freud's legacy, AI as the...

1 Juli 22min

#482 — More From Sam: The Iran Deal, College in the AI Age, Mamdani's DSA, and More

#482 — More From Sam: The Iran Deal, College in the AI Age, Mamdani's DSA, and More

In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss topics from Making Sense Community, including one-world government, the value of a degree as A...

25 Juni 21min

#481 — Sam Harris Receives the 2026 Richard Dawkins Award

#481 — Sam Harris Receives the 2026 Richard Dawkins Award

Richard Dawkins presents Sam Harris with the 2026 Richard Dawkins Award at a live Center for Inquiry event. After the tribute, the two friends discuss consciousness and epiphenomenalism, AI and the Tu...

17 Juni 54min

#480 — The Economics of Everything

#480 — The Economics of Everything

Sam Harris speaks with economist and Substack writer Noah Smith about the U.S. national debt, wealth inequality, and the economic consequences of AI. They discuss the mechanics of debt and inflation, ...

12 Juni 24min

#479 — When Robots Take Over

#479 — When Robots Take Over

Sam Harris speaks with Vinod Khosla about AI, economic disruption, and political risk. They discuss the prospect of mass job displacement, a trillion-dollar policy framework to redistribute AI's gains...

4 Juni 15min

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