123. Gerald Posner — Pharma: Greed, Lies, and the Poisoning of America

123. Gerald Posner — Pharma: Greed, Lies, and the Poisoning of America

Pharmaceutical breakthroughs such as antibiotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. Pharma introduces brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company executives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Pharma reveals how and why American drug companies have put earnings ahead of patients. Shermer and Posner also discuss:

  • how Big Pharma companies conspire to hack the FDA regulations,
  • parsing responsibility for the Opioid crisis between manufacturers, distributors, doctors, and patients,
  • the physiology of addiction and dependency,
  • how Arthur Sackler went from liberal do-gooder to greedy capitalist,
  • the polio vaccine and patenting the sun,
  • how valium and anti-depressants were marketed to men and women differently,
  • how the AIDS cocktail was developed,
  • how Viagra® was discovered,
  • why patents and intellectual property rights do not lead to more innovation,
  • the prospects for a COVID-19 vaccine,
  • the current state of the opioid crisis and how to stem it.

Gerald Posner is an award-winning journalist who has written twelve books, including the Pulitzer Prize finalist Case Closed: Lee Harvey Oswald and the Assassination of JFK and multiple national bestsellers. His 2015 book, God’s Bankers, a two-hundred-year history of the finances of the Vatican, was an acclaimed New York Timesbestseller. Posner has written for many national magazines and papers, including The New York Times, The New Yorker, Newsweek, and Time, and he has been a regular contributor to NBC, the History Channel, CNN, CBS, MSNBC, and FOX News. He lives in Miami Beach with his wife, author Trisha Posner.

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Amanda Knox: Life After the Crime That Wasn’t Hers

Amanda Knox: Life After the Crime That Wasn’t Hers

Amanda Knox spent nearly four years in prison and eight years on trial for a murder she didn’t commit—and became a notorious tabloid story in the process. Though she was exonerated, it’s taken more than a decade for her to reclaim her identity and truly feel free. Amanda’s new book, Free recounts how she survived prison, the mistakes she made and misadventures she had reintegrating into society, culminating in the untold story of her return to Italy and the extraordinary relationship she’s built with the man who sent her to prison. Amanda tells the story of her personal growth and hard fought wisdom, recasting her public reckoning as a private reflection on the search for meaning and purpose that will speak to everyone persevering through hardship.

15 Apr 1h 14min

What Einstein Meant by God: Science, Spirituality, and the Search for Meaning

What Einstein Meant by God: Science, Spirituality, and the Search for Meaning

Albert Einstein remains renowned around the world for revolutionizing our understanding of the cosmos, but very few realize that the celebrated scientist had a deep spiritual side. Einstein believed that one wondrous force was woven through all things everywhere—and this sense of the pervasive sacred influenced every aspect of his existence, from his marvelous science to his passionate pacifism. Kieran Fox studied medicine at Stanford University and holds a doctorate in cognitive neuroscience from the University of British Columbia. He is a physician-scientist at the The University of California, San Francisco, where his research centers on the neural mechanisms and therapeutic potential of meditation practices and psychedelic medicines. His new book is I Am a Part of Infinity. More information: https://www.iamapartofinfinity.com/

8 Apr 1h 46min

What Happened to the Intellectual Dark Web?

What Happened to the Intellectual Dark Web?

Outside of the academics and activists whose ideology came to dominate the West in the second decade of the twenty-first century, arguably no group influenced public discourse as much as the Intellectual Dark Web. Challenging the intellectual and cultural orthodoxies that engulfed universities, the media, and big tech, this group—a loose collective of politically diverse intellectuals, commentators, and scholars critical of political correctness, identity politics, and cancel culture—relied on alternative platforms like podcasts, digital magazines, and YouTube to promote free speech, universal rights, and individual liberty. While the term is most commonly identified with Sam Harris, Ben Shapiro, Jordan Peterson, Bret and Eric Weinstein, and Joe Rogan, the group’s concerns and philosophy extended more broadly to include a wide range of individuals who helped mainstream critiques of “woke” culture and a robust defense of free speech, including Steven Pinker, Michael Shermer, Jonathan Haidt, Dave Rubin, Ayaan Hirsi Ali, and Stephen Fry. The Intellectual Dark Web’s coherence began to unravel in the early 2020s due to internal differences (such as over the response to COVID-19 and climate change), and its full legacy and historical impact are yet to be determined. Jamie Roberts is a lecturer in the Department of Government and International Relations at the University of Sydney. His new book is The Intellectual Dark Web: A History (and Possible Future).

1 Apr 1h 19min

Sex and Beauty: The Extraordinary Implications of Darwin’s Strangest Idea (Matt Ridley)

Sex and Beauty: The Extraordinary Implications of Darwin’s Strangest Idea (Matt Ridley)

In all animals, mating is a deal. But few creatures behave as if sex is a simple, even mutually beneficial, transaction. Many more treat it with reverence, suspicion, angst, and violence. Matt Ridley revisits Darwin’s revelatory theory of mate choice through the close study of the peculiar rituals of birds, and considers how this mating process complicates our own view of human evolution. Ridley also explores the scientific research into the evolution of bright colors, exotic ornaments, and elaborate displays in birds around the world. Charles Darwin thought the purpose of such displays was to “charm” females. Though Darwin’s theory was initially dismissed and buried for decades, recent scientific research has proven him newly right—there is a powerful evolutionary force quite distinct from natural selection: mate choice. In Birds, Sex and Beauty, Ridley reopens the history of Darwin’s vexed theory, laying bare a century of disagreement about an idea so powerful, so weird, and so wonderful, we may have yet to fully understand its implications. Matt Ridley is the bestselling author of The Rational Optimist and Viral: The Search for the Origin of COVID-19 (with Alina Chan). His books have sold over a million copies. Ridley served in the House of Lords from 2013 to 2021 and is a fellow of the Royal Society of Literature, the Academy of Medical Sciences, and an honorary member of the American Academy of Arts and Sciences. His latest book is Birds, Sex and Beauty: The Extraordinary Implications of Charles Darwin’s Strangest Idea.

25 Mars 1h 15min

The Hoax of the Century: Iron Mountain

The Hoax of the Century: Iron Mountain

Phil Tinline, author of the new book Ghosts of Iron Mountain, explores the origins of the infamous Report from Iron Mountain, its role in conspiracy culture, and its lasting influence on perceptions of the military-industrial complex. The conversation also examines Holocaust denial, nativism, and the evolution of deep state conspiracies, highlighting the power of narratives in shaping democracy and public trust. Tinline is a British freelance writer and documentarian. His book The Death of Consensus: 100 Years of British Political Nightmares was named The Times (London) Politics Book of the Year. Over two decades at the BBC, he has produced and presented acclaimed documentaries on the impact of political history on contemporary life.

18 Mars 1h 42min

Does the West Need a Religious Revival? (Shermer Solo)

Does the West Need a Religious Revival? (Shermer Solo)

A few reflections on religion following The Free Press debate in Austin, TX on February 27, 2025. Michael Shermer and Adam Carolla (atheists) faced off against Ayaan Hirsi Ali and Ross Douthat (Christians). You can watch the debate here: https://www.thefp.com/p/watch-does-the-west-need-a-religious

11 Mars 37min

Money, Lies, and God

Money, Lies, and God

Michael and Katherine Stewart discuss the rise of religious nationalism in America, its impact on public education, and the broader implications for democracy. They explore the strategies employed by religious groups to infiltrate public schools, the culture wars surrounding education, and the divisive nature of the New Right. Katherine Stewart is the author of The Power Worshippers: Inside the Dangerous Rise of Religious Nationalism, the award-winning book upon which the documentary feature, God & Country, produced by Rob Reiner, is based. She has covered the intersection of faith and politics for over 15 years. Her new book is Money, Lies, and God.

11 Mars 1h 37min

Who Counts? Ethics in the Treatment of Animals and AI

Who Counts? Ethics in the Treatment of Animals and AI

Michael Shermer and Jeff Sebo explore moral philosophy, focusing on animal rights, sentience, and consciousness. They discuss the definitions of morality, ethical pluralism, and the divide between consequentialism and deontology. The conversation examines who belongs in our moral circle, the ethics of insect farming, the future of animal agriculture, abortion, and whether advanced AI could be considered sentient beings or even co-citizens.

8 Mars 1h 27min

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