Peptides for Fat Loss w/ CanLab: Setmelanotide, AOD 9604, FRAG17691, Tesamorelin, CJC 1295 NO Dac

Peptides for Fat Loss w/ CanLab: Setmelanotide, AOD 9604, FRAG17691, Tesamorelin, CJC 1295 NO Dac

In this Interview, Jean-Francois Tremblay, owner of CanLab and I dig in to one of the new darlings of the peptide world - Tesamorelin and a less known but possibly just as effective other option - Setmelanotide - an offshoot of the better known Melantonan 2. We also cover AOD 9604, FRAG 17691 and CJC1295 ...and why you probably want to avoid the version with DAC (drug affinity complex)... We start with a chat about how if you're after lasting results there's really no way to avoid optimizing your diet, moving more, optimizing sleep etc... but these peptides might just help to speed things along and ease some of the bumps along the way.

Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your health care provider. Always seek the advice of your physician or health care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

Show Notes:

Keto Calorie

Peptides Help with Fat Loss Body Recomposition Growth Hormone unregulated by Fat Loss peptides like FRAG 17691 or AOD9604 (just one amino acid difference) help to mobilize fatty acids in the fat cell – but need to be in calorie/energy deficit for it to stay out

Consistency and sticking to your plan is the ultimate secret sauce…

Why Canlab combines Frag and AOD 9604 More about Frag and AOD….are they the same or different? AOD lacks one tyrosine…means that it lasts longer…whereas Frag uses more up front and gets metabolized faster…..

Tesamorelin…..what it does….

The skinny on Tesamorelin….it's not about Tesa it's about the growth hormone release….

Re Muscle Gains attributed to Peptides….in studies re old people it's about bringing back muscle you once had…. Hormone replacement therapy is at the foundation of reclaiming muscle mass GH good for muscle sustaining (vs growth) and tissue repair (but doesn't hold a candle to BPC and TB4)

Tesamorelin – origins – where it came from originally….very close to CJC 1295 (Mod IGRF 121 is actually CJC 1295 without dac). and other Growth Hormone Secretagogues.

The difference between Tesa and CJC not really all that great….why some people may be promoting Tesa over CJC 1295 the magic is in the dose.

Difference about with Dac and without Dac. With Dac too many peaks of growth hormone (similar to MK 677….increases risk of insulin resistance…..why is the Dac long lasting…binds to albumin in the blood ….which is problematic as there may have been relationship to blood cancer seen in certain studies….so better to use without DAC…just use multiple times a day if necessary

Post workout (3) is a good time…but pre bed(1), pre workout and first thing in the morning (2) are all better

Setmelanotide – another derivative of alpha MSH (Melanotan, melanotan 2, PT141) Basically prioritizes appetite suppression over tanning and sexual enhancement..they all create a tan just to varying degrees…. SM get appetite curbing (some sexual stim)…increases metabolic rate by about 6%, without increasing HR or BP…. On average can expect about 1 lb a week fat loss…. Many reports of people using it with good results – safe track record…..Clinical studies went for 12 months

Do not start at full dose of 1.5mg a day….start at .5 1-2 days then 1.0mg for a couple of days and then increase to full dose to avoid possible /nausea In studies – they changed nothing else….and saw results but it's likely that as people lost weight they may have started to move more etc…

At this point best method for most peptides is SubQ over oral….Intranasal may work but need to use higher dose (aka PT141 1 mg is SubQ and 2mg is IntraNasal)

Tesofensine – not a peptide acts on dopamine and AC receptors in the brain so needs to be used with great caution Please note that this video is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Peptides are for the most part classified as research chemicals so should not be used on humans. Before changing your diet or using any new supplement make sure to consult with your care provider. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition.

Avsnitt(382)

#304: UnMASKING GMO Dangers: The Science Monsanto Wants to Hide | Why You Should Eat Organic Whenever Possible With Jeffrey Smith

#304: UnMASKING GMO Dangers: The Science Monsanto Wants to Hide | Why You Should Eat Organic Whenever Possible With Jeffrey Smith

Today we're lifting the lid on the food industry's best-kept secrets with Jeffrey Smith. Ever wonder why gut issues, anxiety, or even insomnia are on the rise? It turns out, that GMOs and glyphosate—the chemical found in everything from cereal to wine—might have something to do with it. Jeffrey Smith is the Founder & Executive Director of the Institute for Responsible Technology, a Best Selling Author Seeds Of Deception, and a Filmmaker. He reveals the jaw-dropping results of a study where thousands of people saw improvements in 28 conditions after switching to organic. Stick around to learn why glyphosate has been called a "Darth Vader chemical" and why your pantry might be plotting against you. Resources: Glyphosate Report Non-GMO Shopping Guide…And When You Dine Out What I Discuss: NeuralRx Advertisement ... 00:01:59 Discussion on GMOs and glyphosate ... 00:06:17 The rise of certain diseases and their correlation with GMOs and glyphosate ... 00:26:43 BT toxin explanation and its risks ... 00:43:22 Impact of glyphosate on gut health and mineral absorption ... 00:53:30 Second advertisement: Youth Daily by Young Goose ... 00:49:18 Healing prospects with an organic diet ... 00:56:17 Dangers of gene editing (GMO 2.0) ... 01:03:32 Urgent need for regulatory action and support for IRT ... 01:16:01 Sponsors: Wizard Sciences (Neural Rx) - Neural Rx isn't just about a quick boost. It's designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com. Young Goose (Youth Daily) - Youth Daily activates your skin's anti-aging genes, shields against environmental nasties by day and tackles signs of aging by night. Visit Younggoose.com and use code NAT20 on your first order, or, if you're an existing customer 5NAT will reward you with an ongoing discount. SiPhox - The only comprehensive at-home blood testing solution that lets you check up to 50 biomarkers from your very own home. No travel, no appointments, just a few drops of blood on a card and you're set. Visit SiPhoxhealth.com/nat and you get 20 % off your first order using code NAT. Nat's links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

28 Jan 1h 21min

#303: The Fasting PLAYBOOK: Nathalie Niddam Reveals Top Strategies for Health & Longevity

#303: The Fasting PLAYBOOK: Nathalie Niddam Reveals Top Strategies for Health & Longevity

In this episode, I discuss the fascinating and multi-faceted practice of fasting. Today I uncover the various types of fasting—from intermittent fasting and water fasting to the more intensive dry fasting and the innovative Fasting Mimicking Diet. *More about the Fasting Mimicking Kit at prolonlife.com/Nat for 20% off (applied at checkout). If you're in Canada you can just go to Prolonfast.ca and use code NAT20 to save. What I Discuss: Types of Fasting Explained ... 01:15 Intermittent Fasting and Eating Windows ... 02:45 Skipping Breakfast vs. Skipping Dinner ... 04:10 Different Intermittent Fasting Schedules (16/8, 18/6, 20/4) ... 06:05 Benefits of Longer Fast Durations ... 09:30 Water Fasting and Its Effects ... 10:45 Dry Fasting: Risks and Rewards ... 12:20 Alternate Day Fasting Overview ... 14:50 Protein Sparing Modified Fasts ... 17:15 Introduction to Bone Broth Fasting ... 19:00 Fasting Mimicking Diet Explained ... 21:40 Significance of Nutrient Density and Sleep ... 24:25 Enhancing Fasting with Peptides, Bioregulators, and GLP1s ... 26:10 Consulting Medical Providers Before Fasting ... 28:50 Made Possible By Our Amazing Sponsor: BiOptimizers: It's the only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Go to bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

24 Jan 34min

#302: If You Have Creeky or Painful Joints and BIG Dreams of Staying Active, These Nonsurgical Solutions Are The NEW Way Forward - With Dr. Jeff Gross

#302: If You Have Creeky or Painful Joints and BIG Dreams of Staying Active, These Nonsurgical Solutions Are The NEW Way Forward - With Dr. Jeff Gross

In this episode, I'm joined by the incredible Dr. Jeff Gross from ReCELLebrate, a top neurosurgeon specializing in non-surgical regenerative medicine. Dr. Gross is here to debunk some long-standing myths, most notably the belief that cartilage can't regrow. What We Discuss: Introduction to regenerative medicine and stem cells ... 00:50 Stem cell differentiation and their potential ... 03:45 Patient preparation before therapies ... 06:20 Exosomes and their therapeutic benefits ... 09:05 Applications in joint and sports injuries ... 12:30 Treating osteoarthritis and cartilage regeneration ... 16:10 Bone edge vs. joint injections for osteoarthritis ... 19:15 Legalities and misconceptions about stem cell therapies ... 28:30 Safety with stem cell treatments ... 31:45 PRP, adipose products, and amniotic fluid in therapies ... 34:15 Dr. Gross's professional journey in regenerative medicine ... 37:35 Dr. Gross's contact information for consultations ... 42:20 Final thoughts and future advancements ... 45:00 Made Possible By Our Amazing Sponsor: Puori - Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order. BEAM Minerals - Their Liquid Formula delivers the perfect mix of all these sleep supporting minerals. Visit beamminerals.com and use code NAT20 to get 20% off your order. Young Goose - Get 10% off your first order with code NAT10 and this link. And save on future orders with code 5NAT using this link. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

21 Jan 1h 15min

#301: The 5-Day Reset - How To Get All The Benefits Of Fasting Without Feeling Hungry With Renee Fitton

#301: The 5-Day Reset - How To Get All The Benefits Of Fasting Without Feeling Hungry With Renee Fitton

In this episode, Renee Fitton from Prolon Life joins me in a discussion about how to gain all the benefits of fasting without feeling hungry and giving up! Learn more about Renee Fitton and her Fasting Mimicking Kit at prolonlife.com/Nat, where podcast listeners get 20% off at checkout! In Canada? Visit Prolonfast.ca and use code NAT20 to save. What We Discuss: Nathalie's new health initiative announcement ... 00:45 Encouragement to start fasting anytime ... 02:00 Invitation to join the group fast, March 2nd ... 05:00 Caffeinated beverages and fasting ... 07:15 Contents of ProLon five-day fast ... 08:45 L drink benefits and tips ... 09:30 Fasting recommendations ... 10:15 Muscle-sparing properties of FMD ... 12:30 Dr. Longo's research findings ... 13:15 Recommendation to start with three FMD cycles ... 14:00 FMD's benefits in oncology ... 14:45 Combining GLP-1s with FMD ... 20:00 Intermittent fasting and circadian rhythms ... 21:45 Nat's experience with ketosis ... 32:15 Bio-individuality in fasting responses ... 33:00 Safety of fasting mimicking diets ... 35:15 Made Possible By Our Amazing Sponsors: Mitopure from Timeline: Improve your cellular health by taking Mitopure in its simplest form with two vegan softgels daily for the recommended dose of Urolithin A (500mg of Mitopure). Visit timeline.com/nat10 for 10% off. SOLTEC: Struggling with restless nights and daily stress? Introducing the Soltec System—a revolutionary solution designed to transform the way you sleep and manage stress. Visit www.soltechealth.com for $100 off your purchase using code LONGEVITY. Experience the difference for yourself with a 60-day risk free trial. LVLUP: The secret to CREvolution? It's all about GAA. This powerful compound helps you get more creatine into your cells faster than traditional creatine. Ready to crush your next workout? Head to lvluphealth.com and use the code NAT for 15% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

17 Jan 1h 23min

#300: Breast Cancer Overdiagnosis, Mammogram Myths, The REAL Risks For Women And Bold NEW Alternatives With Dr. Jenn Simmons

#300: Breast Cancer Overdiagnosis, Mammogram Myths, The REAL Risks For Women And Bold NEW Alternatives With Dr. Jenn Simmons

Today, we dive into a thought-provoking discussion with Dr. Jennifer Simmons, a breast cancer surgeon turned functional medicine oncologist, who is redefining breast cancer diagnosis, treatment, and screening. Use Jenn's code: Drjenn20 for 20% of the Auria test. What We Discuss: Critique of Mammograms and Below-Average Efficacy ... 03:15 Canadian Breast Cancer Screening Trial Findings ... 06:50 Concerns with Overdiagnosis in Mammograms ... 08:25 Consequences of Unnecessary Breast Cancer Treatments ... 11:40 Absence of Predictive Tests for Cancer Aggressiveness ... 15:10 Debunking the Myth of Early Detection's Efficacy ... 18:00 Dense Breast Tissue and Mammogram Limitations ... 21:30 Risks Associated with Mammogram Radiation ... 24:10 Importance of Lymphatic System Health ... 29:00 Alternative Approaches to Monitoring Breast Health ... 32:20 Holistic Benefits of Rebounding, Dry Skin Brushing ... 35:45 Criticism of Restrictive Bras and Advice on Usage ... 38:10 Bioidentical Hormone Replacement Therapy (HRT) Insights ... 41:20 Misconceptions About Estrogen and Breast Cancer ... 45:05 Introduction to the Mitolux Device ... 51:50 Dietary and Physical Recommendations for Optimal Health ... 54:20 History and Long-term Impact of Breast Health ... 1:09:05 Pharmaceutical Dependencies and Lifestyle Impact ... 1:12:20 Arguments Against Over-treatment of DCIS ... 1:15:30 Innovative Breast Cancer Screening Tests: AURIA and QT Scan ... 1:18:50 Challenges with Current Breast Cancer Treatments ... 1:22:10 Ethical Considerations in Breast Cancer Treatment ... 1:25:45 Made Possible By Our Amazing Sponsor: SiPhox - SiPhox Health offers at-home blood testing solutions, providing custom supplements based on your personalized blood work. Visit http://SiPhoxhealth.com/nat and use code LONGEVITY to save on your test. Manukora - Looking to boost your immunity and gut health with nature's finest? Manukora Honey, sourced from New Zealand, brings you high-quality honey rich in health benefits. Visit this link http://manukora.pxf.io/kO0rJN to enjoy a special discount with the code LONGEVITY. Wizard Sciences - Ready to upgrade your brain game? Unlock your cognitive potential with Neural Rx. Use code NAT15 at checkout to get 15% off your purchase. Don't wait—start the year with a sharper, more focused mind. Visit Wizardsciences.com Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

14 Jan 1h 33min

#299: 2025 Health Breakthroughs - New GLP-1 Topics, Home Testing Innovations, and Cancer Detection with Nathalie Niddam

#299: 2025 Health Breakthroughs - New GLP-1 Topics, Home Testing Innovations, and Cancer Detection with Nathalie Niddam

In today's episode, I reveal the top health trends of 2025 that you can't afford to miss. What We Discuss: 2025 Trends in Health ... 01:15 GLP1s: Managing body composition with emerging variations ... 01:30 Importance of lifestyle factors such as diet and exercise alongside GLP1s ... 03:45 Home Testing Innovations ... 05:05 Theriom's Aristotle Test and upcoming microbiome test ... 05:25 MI Screen: Non-invasive mitochondrial function test ... 07:40 True Diagnostic: The Harmony Test for aging ... 09:00 Syphox: Comprehensive blood analysis innovation ... 10:45 Vaitrakt: Affordable gut microbiome test ... 11:35 Prodrome Science Test: Practitioner guided health insights ... 13:20 Early Cancer Detection Advances ... 15:00 Auria Test: Tear-based breast cancer detection ... 16:50 QT Scan: Imaging dense breasts non-invasively ... 18:35 Cardiovision Care: Predictive cardiovascular disease test ... 20:10 Emerging Technologies in Peptides and Bioregulators ... 21:45 Enhanced bioavailability through skin delivery ... 22:00 Addressing past traumas and experiences for holistic health ... 27:25 Closing Remarks and Teasers for Future Episodes ... 31:30 Made Possible By Our Amazing Sponsor: Mitopure from Timeline: Improve your cellular health by taking Mitopure in its simplest form with two vegan softgels daily for the recommended dose of Urolithin A (500mg of Mitopure). Visit timeline.com/nat10 for 10% off. That's timeline.com/nat10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

10 Jan 33min

#298: Aging Well with Jean Fallacara: Simple Habits, Tech Hacks, and Longevity Tips

#298: Aging Well with Jean Fallacara: Simple Habits, Tech Hacks, and Longevity Tips

Today's guest, Jean Fallacara, is part scientist, part philosopher, and 100% here to help us rethink mornings, aging, and what it means to truly live well. What We Discuss: Biohacking challenges: optimizing versus expensive elite pursuit ... 09:26 Lifestyle shift is about sustainable, basic habits ... 13:56 Embrace natural lifestyle over modern "biohacking" ... 17:17 Calm mornings improved her busy, chaotic life ... 24:51 Morning meditation, mindfulness, present focus, no projections ... 28:39 Be the pilot of your own life ... 35:09 Age-defying calisthenics through mind-body connection ... 39:56 Gut health impacts resolutions; probiotics enhance success ... 45:56 Adjusting age impacts health, but basics remain ... 54:37 Fasting activates autophagy, aiding natural fat loss ... 59:08 Fasting weekly now, lost weight too fast ... 01:01:41 Prioritizing sleep improves well-being despite noise ... 01:06:45 Challenged, not sore; testing improved suit technology ... 01:12:03 AI impacts research, urges responsibility for future ... 01:20:05 AI-powered platform offers personalized supplement recommendations ... 01:22:44 Made Possible By Our Amazing Sponsors: Zona Health - A small, handheld device that you squeeze using the science of isometric exercise. In just a few minutes a day, it can naturally boost blood flow, reduce stress, and lower your blood pressure. Visit zona.com, and use code NAT24 to save $100 on your Zona Plus. Puori - Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order. Or, if you want to go big and get nearly a third off with a subscription, you can do that too. Head to Puori.com/NAT and use promo code NAT at checkout. Just Thrive - The only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90 day bottle Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

7 Jan 1h 24min

Episode #297: You Want The Formula For Long-term Success with GLP-1's (aka Ozempic)? It's All Here In This, Our Most Popular, Episode of 2024 with Gus Vickery

Episode #297: You Want The Formula For Long-term Success with GLP-1's (aka Ozempic)? It's All Here In This, Our Most Popular, Episode of 2024 with Gus Vickery

Are you tired of yo-yo dieting and struggling to achieve lasting weight loss? Have you heard about the buzz surrounding GLP-1 agonist medications like semaglutide and tirzepatide but aren't sure how to effectively incorporate them into your journey? In today's episode, Dr. Gus Vickery and I discuss the effective use of GLP-1 agonist medications like semaglutide and tirzepatide for sustainable weight loss. He emphasizes the need for a mindset shift, viewing these drugs as powerful tools to catalyze positive changes rather than easy fixes or crutches. Dr. Vickery explains that these medications provide leverage to implement foundational healthy habits and that the key to success lies in focusing on nutrient sufficiency, not just calorie restriction. We also discuss concerns surrounding GLP-1 medications, such as the potential for muscle loss and the risk of regaining weight after discontinuing the drugs. He shares strategies to mitigate these issues, including resistance training, adequate protein intake, and gradual dose reduction when nearing one's goal weight. Dr. Gus Vickery is an author, speaker, and the founder and directing physician of Authentic Health in Asheville, North Carolina. He established his practice with a commitment to delivering holistic, compassionate, and evidence-based care. Thank you to our sponsors for making this episode possible: BiOptimizers: BiOptimizers: Go to bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. What We Discuss: 04:00 Understanding the Power of Peptides 07:45 The Underlying Benefits of Peptides 12:59 Addressing Concerns about Side Effects 29:06 The Right Way to Use Peptides 30:06 Hormone Therapy and Peptides 34:12 Nutrient Sufficiency and Protein 41:17 The Impact of Fasting and Gut Health 45:33 Addressing Microbiome Balance 58:56 The Pace of Fat Loss and Patience 59:42 Pushing Through Plateaus and Delicate Nervous System 01:07:13 Managing Hormetic Stress and Resting the Nervous System 01:09:00 Choosing Carbs or Fats and Individualization Key Takeaways: Peptides can be a powerful tool for improving body composition and metabolic health. It is important to understand the proper use of peptides and not rely on them as a quick fix or easy way out. Peptides have a range of benefits, including improving insulin sensitivity and reducing fatty liver disease. Concerns about side effects and risks should be weighed against the potential benefits and individual circumstances Find more from Dr. Gus Vickery: Website: https://drgusvickery.com/ Authentic Health Book: https://drgusvickery.com/book/ Instagram: @drgusvickerymd Youtube: The Family Doctor Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Join Nat's Membership Community: https://www.natniddam.com/bsp-community Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 Instagram: https://www.instagram.com/nathalieniddam/ Website: www.NatNiddam.com Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance

3 Jan 1h 22min

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