KetoneAid - Deep Dive on Ketone Esters  with Frank Llosa   –Ketone Esters fill a critical role in human physical and cognitive performance…could they even play a role in treating viral infections?

KetoneAid - Deep Dive on Ketone Esters with Frank Llosa –Ketone Esters fill a critical role in human physical and cognitive performance…could they even play a role in treating viral infections?

In this episode I deep dive into the fascinating world of ketone esters with Frank Llosa one of the most passionate entrepreneurs you will meet. By now, most of us have heard of the ketogenic diet – at its center are 3 fascinating molecules called Ketones – in this case, we are talking about beta hydroxybutyrate or BHB. While it is often talked about as a fuel source, it turns out the BHB is so much more than that as it is also an important signalling molecule that has wide ranging benefits to the human body. Ketone Esters are known for tasing awful and costing a small fortune but through utter dedication Frank has managed to make them palatable and more affordable in order to make this important compound accessible to more people including researchers who are still uncovering the many ways they can benefit human health.

Links

https://shop.ketoneaid.com

Use Promo Code Longevity to save on shipping!

Frank Llosa' s story – how he first became interested in Ketone Esters and his surprising connection to Dr Veech, a pioneer in Ketone research and science

6:35 Frank's first pitch to Venture Capitalists on marketing Ketone Esters was not exactly a winner…

7:20 The first competitive athletes who used Ketone Esters to improve their performance and how Frank ended up providing the initial seed capital to bring Ketone Esters to the market

9:25 The journey of bringing KetoneAid to market from sending them to athletes to Indiegogo campaigns…

14:47 How much of the KE1 and the KE4 do you actually need to use in one sitting and cost?

16:51 The different sports/athletes using Ketone Esters from Triathletes to half mile runners, how and why….is it helping muscles or brain?

18:30 Talking about Ketone esters and the brain – mouse studies that show that Ketogenic Diet can heal traumatic brain injuries in mice

20:45 The brain energy gap starts at age thirty

25:22 Ketone esters for Tour de France Athletes delivered 15% faster time trials…

25:52 Ketone Esters for recovery and the importance of timing Ketone esters right during athletic competitions…

27:02 How Greg Henderson former Tour de France athlete discovered that Ketone Esters not only materially improved his performance but also affected his recovery the next day….

29:10 How should regular people use Ketone Esters around their workouts? No need to be Keto if you're using it fasted (and are used to fasted workouts). For alttitude workouts/results…. For hill workouts….

30:37 The muscle groups that can actually use ketone esters and how this might impact how you train when using ketone esters

34:47 Ketone esters post workout for recovery and to manage excess caloric intake ….and to bring your brain online post workout.

38:02 the interplay between Ketone esters and glucose at the end of a race/event….it's all about lasting power sometimes even at the expense of peak performance..

39:36 Using Ketone esters for cognitive performance – a couple of real life examples …

42:57 The good news/bad news of Ketone Esters and Caffeine…augmentation and replacement

46:12 Exploring why some people may respond better or faster to ketone esters than others – ketone transporters

50:22 Franks role in getting a (30 pages!) paper written on how Ketone esters may be helpful in supporting COVID19 patients…next step….clinical trials under way as we speak!!

53:19 Setting up the first clinical trial happening in Denmark to see how ketone Esters can support the heart in patients with severe COVID19 symptoms

53:59 The link between high blood glucose levels and worse COVID19 outcomes…could a Keto diet help long haulers?

1:01 Using Ketoneaid before bedtime for sleep…

1:04 A theory on why KetoneAid might be helpful for sleep….

1:07 How Frank occasionally uses Ketones to pre-emptively mitigate the negative impact of insufficient sleep

1:08 Ketones may help to protect from harmful effects of radiation – for people living near nuclear power plants, when flying….an unpublished mouse study on how ketones massively increased survival rate of mice exposed to deadly levels of radiation.

1:13 Ketones and weight loss – how NOT to use them…

1:14 The difference between having ketones in your blood and actually being in ketosis.

1:16 Adopting a ketogenic diet before starting to use exogenous ketones of any kind…

1:19 Do people need to be on a ketogenic diet to get benefits from ketone esters?

1:20 Using Ketone Esters to fuel the brain energy gap, to extend a fast

Links:

KetoneAid.com

Promo Code: Longevity to save up to $20 off shipping

Disclaimer: This podcast is provided and intended for information purposes only, none of the information is to be taken or used as medical advice. Before making any changes to your lifestyle, supplementation or nutrition please consult with your medical provider.

Avsnitt(382)

#344: Mindset Over Mortality: Top Breakthroughs for EXTREME Longevity (And How to Think Like an Immortal) with James Strole

#344: Mindset Over Mortality: Top Breakthroughs for EXTREME Longevity (And How to Think Like an Immortal) with James Strole

Welcome back to the Longevity Podcast! In this episode, I have the pleasure of sitting down with James Strole, a beacon in the radical longevity space and the visionary founder behind People Unlimited and RAADfest. James shares the personal journey that led him into the world of life extension—shaped by a spiritually open-minded mother, a pivotal loss, and a lifelong desire to challenge the idea that aging is inevitable. Get 10% off your tickets to RAADfest using code: "niddam" What we discuss: James Strole's personal journey to radical longevity ... 00:04:00 Spiritual roots and early inspiration ... 00:10:00 Transition from spiritual to scientific approaches ... 00:13:00 Launching RAADfest and the shift toward hard science ... 00:16:00 Evolution of the longevity movement over the decade ... 00:21:00 Access to longevity innovations and RAAD Clinics ... 00:22:00 Most exciting developments: gene therapy and age reversal ... 00:24:00 Daily longevity pillars: diet, movement, mindset ... 00:26:00 Mindset and embracing the possibility of immortality ... 00:35:00 Overcoming skepticism and "against nature" arguments ... 00:41:00 Societal implications of extreme longevity ... 00:44:00 Are we at the tipping point? The "era of immortality" ... 00:47:00 Advice for newcomers: join the conversation and community ... 00:50:00 Our Amazing Sponsors: NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Mitoblue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you're eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

17 Juni 56min

#343: The BODY Remembers: Secrets to Fascia, Trauma & Radical Healing (Neural Therapy, Osteopathy, and the Power of Emotions) | Dr. Tudor Marinescu Reveals All

#343: The BODY Remembers: Secrets to Fascia, Trauma & Radical Healing (Neural Therapy, Osteopathy, and the Power of Emotions) | Dr. Tudor Marinescu Reveals All

Welcome back to the Longevity Podcast! I'm so excited to share today's episode with you, because it's one that's deeply personal and truly inspiring. I had the pleasure of sitting down with Dr. Tudor Marinescu, a remarkable physician I met during one of the Sedona retreats I co-host. Although he began his career as a trauma and orthopedic surgeon in Germany, Dr. Tudor's path soon led him far beyond traditional medicine. Now, he's known for his transformative work in osteopathy, neural therapy, and the exploration of how trauma—both physical and emotional—can shape our health and longevity. Find an amazing practitioner like Dr. Tudor near you: https://klinghardtinstitute.com/art-practitioners/ for A.R.T https://cranialacademy.org/find-a-physician/ for Osteopathy https://naant.org/by-any-word/ for Neural therapy https://www.doctortudor.com/ What we discuss: Dr. Tudor's pivotal moments and holistic shift ... 00:08:23 Osteopathy principles and the body as a memory bank ... 00:14:30 How emotions, trauma, and fascia affect healing ... 00:18:58 History of mind-body separation in medicine ... 00:21:38 Integration of spiritual, emotional, and physical healing ... 00:26:11 Understanding fascia: structure, hydration, and movement ... 00:38:00 Neural therapy and procaine's role in trauma release ... 00:54:08 Breaking trauma cycles: autonomic nervous system reset ... 00:59:54 Linking physical symptoms to emotional and spiritual health ... 01:09:38 Blending allopathic with holistic and ancestral medicine ... 01:20:46 How to find qualified holistic practitioners ... 01:26:39 Dr. Tudor's contact info and Sedona retreat details ... 01:31:07 Final thoughts and disclaimer ... 01:33:53 Our Amazing Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. BEAM Minerals - are one of the most overlooked contributors to a healthy gut. They help feed and support your microbiome. Research shows that good gut bacteria rely on essential minerals like calcium, magnesium, zinc, iron, and phosphorus to thrive.. Head over to www.beamminerals.com and use code NAT20 for 20% off your first order and give your gut the simple support it deserves! Ultimate GI Repair by LVLUP Health - Whether you're struggling with digestive discomfort or want to strengthen your gut health, Ultimate GI Repair provides the comprehensive support your body needs to restore balance. Filled with key peptides for healing! Visit https://lvluphealth.com/ and use code NAT at checkout for 20 % off. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

13 Juni 1h 35min

#342: Unlocking The Secret Code To Fasting: The Biohack for Hunger, Longevity & Energy (How Scientists Are Hacking Your CELLS) | Chris Rhodes

#342: Unlocking The Secret Code To Fasting: The Biohack for Hunger, Longevity & Energy (How Scientists Are Hacking Your CELLS) | Chris Rhodes

Welcome back to the Longevity Podcast! I'm so excited for today's episode, where I sit down with Chris Rhodes—nutritional biochemist, fasting researcher, and CEO of Mimio Health—to dive deep into one of the most fascinating emerging topics in longevity science: fasting mimetics. If you've ever wanted to get the regenerative, anti-inflammatory, and health-boosting effects of fasting, but struggled to actually fast for 36 hours or more (trust me, I get it!), this conversation is for you. Listeners of this podcast can visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. What we discuss: Meet Chris Rhodes and his biomimetic research journey ... 00:05:18 Unlocking fasting benefits without prolonged fasting ... 00:09:10 Supplements vs. pharmaceuticals for longevity ... 00:10:53 Fasting protocols, timing, and metabolic switching ... 00:15:23 Risks of fasting, evolutionary adaptation, and muscle/bone loss ... 00:18:34 Ketones, brain energy, and cognitive adaptation ... 00:22:48 How fasting activates longevity and repair pathways ... 00:26:23 Key cellular pathways: AMPK, mTOR, NAD, sirtuins ... 00:28:04 Mimio research: discovering and testing fasting metabolites ... 00:33:35 The four main fasting mimetic molecules explained ... 00:42:04 Practical benefits: who should use fasting mimetics & safety ... 00:59:00 Mimio in use: hunger control, GLP-1 support, and older adults ... 01:03:37 Our Amazing Sponsors: Qualia NAD+ - This vital molecule powers cellular energy, supports DNA health, aids detox, and helps keep your body remain youthful. Visit qualialife.com/nathalie to try Qualia NAD+, backed by a 100-day money-back guarantee, and use promo code NATHALIE for 15% off! OraltidePro - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. Check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order. Bio-Shield by Young Goose - A broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

10 Juni 1h 20min

#341: 5 Underrated Longevity Practices You Should Start Doing… Yesterday | With Nat Niddam

#341: 5 Underrated Longevity Practices You Should Start Doing… Yesterday | With Nat Niddam

Welcome back to the Longevity Podcast! I'm your host, Nathalie Niddam—nutritionist, human potential and epigenetic coach, and I'm excited to share another solo episode with you. Today, I'm diving into a topic that really resonated with my community on Instagram: five essential habits I wish everyone in their 40s (and honestly, any age!) knew to set themselves up for better health and longevity—without spending a dime. Resources from the episode: • Grounding – The universal anti-inflammatory remedy • Associations between bedtime eating or drinking, sleep duration and wake after sleep onset: findings from the American time use survey • Meal Timing and Anthropometric and Metabolic Outcomes • Meal Timing, Aging, and Metabolic Health • Obstructive sleep apnea and neurodegenerative diseases: A bidirectional relation • Investigation on the Effect of Oral Breathing on Cognitive Activity Using Functional Brain Imaging What we discuss: Digestive bitters before meals: benefits and how to use ... 00:02:10 Digestive bitters: impact on digestion, absorption, and immune system ... 00:04:01 Digestive bitters: sources, supplements, and usage tips ... 00:08:17 Training your glymphatic system for brain health ... 00:09:12 Tips to support glymphatic drainage: sleep, exercise, hydration, nutrition, sleep position ... 00:10:19 Grounding: definition, science, and health impact ... 00:13:39 How to ground in urban environments; grounding sheets and tools ... 00:17:08 Eating dinner three hours before bed: why and how ... 00:19:02 Early dinner vs. skipping breakfast for metabolic health ... 00:21:36 Circadian rhythm alignment tips and jet lag hacks ... 00:24:05 Nasal breathing vs. mouth breathing: importance and intro to solutions ... 00:24:36 Mouth breathing risks, sleep apnea, and cognitive implications ... 00:26:52 Practical tools and professionals for correcting mouth breathing ... 00:29:12 Summary of the five key longevity tips ... 00:31:59 Our Amazing Sponsors: MitoBlue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically—Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

6 Juni 33min

#340: Dave Asprey on Biohacking, Longevity, and Living to 180 (Kale Is Out, Stem Cells Are In) | The Longevity Revolution Explained

#340: Dave Asprey on Biohacking, Longevity, and Living to 180 (Kale Is Out, Stem Cells Are In) | The Longevity Revolution Explained

I had the chance to sit down with one of the original pioneers of the biohacking movement: Dave Asprey. You probably know Dave as the founder of Bulletproof, the mastermind behind putting butter in coffee, and the creator of Upgrade Labs and the Biohacking Conference. He's also a four-time New York Times bestselling author. What we discuss: Biohacking's relationship with longevity and functional medicine ... 00:10:47 The importance of energy, joy, and personalization in longevity ... 00:14:28 Democratizing lab tests and health optimization with AXO Health ... 00:24:00 Most common health imbalances: thyroid, hormones, minerals ... 00:33:25 Danger Coffee and foundational supplement protocols ... 00:39:43 Pitfalls of oversimplification in health and biohacking ... 00:45:52 Making advanced therapies and tech more accessible ... 00:53:23 Ethical and societal considerations in radical longevity ... 01:07:00 Where to find Dave Asprey and closing remarks ... 01:11:58 Our Amazing Sponsors: Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you're eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit shop.timeline.com/NAT10 and use code NAT10 for 10% off. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

3 Juni 1h 11min

#339: Clean Supplements and Protein Powders: What Every Health-Conscious Consumer Needs to Know With Oliver Amdrup-Chamby

#339: Clean Supplements and Protein Powders: What Every Health-Conscious Consumer Needs to Know With Oliver Amdrup-Chamby

I'm joined today by Oliver Amdrup-Chamby, the co-founder of Puori and a true trailblazer in supplement transparency and quality. We break down everything you need to know to become a more informed consumer, from how to avoid hidden contaminants like heavy metals, pesticides, and microplastics, to why oxidation in fish oil is such a big deal, and the real story behind protein powders—especially the plant-based ones. Listeners of this podcast get 20% off of Puori protein, a one-time purchase or if you choose the already discounted subscription, you get almost a third off the price! Visit Puori.com/NAT and use my promo code NAT. What we discuss: Supplements: contamination, purity, and Danish regulation ... 00:08:46 Fish oil: contaminants, microplastics, and oxidation ... 00:12:37 Fish oil quality: what to look for ... 00:15:19 Protein needs, trends, and bioavailability ... 00:24:08 Whey protein vs. plant protein ... 00:27:30 Making protein accessible for families ... 00:31:56 Heavy metals in protein powders ... 00:37:04 Sourcing and batch-level testing ... 00:41:19 Flavorings, sweeteners, and ingredient transparency ... 00:52:10 Tips for selecting clean protein and fish oil ... 01:07:36 Encouraging transparency and consumer advocacy ... 01:11:14 Our Amazing Sponsors: Profound Health - - Nature's Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They're manufactured in the UK. They're GMP and HACCP certified and FDA-compliant. Whatever your health needs, there's a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. CAROL Bike - With its cutting-edge, science-backed method, CAROL Bike can boost your VO2max by 12% in just 8 weeks—essentially rewinding your fitness clock by a decade. The folks at CAROL Bike are offering a 100-day FREE trial! Visit http://carolbike.pxf.io/Nat or use code NAT100 for a free 100-day trial. Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use my code NAT15 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025 Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

30 Maj 1h 12min

#338: How the Sun ACTUALLY Impacts Skin Aging and Cancer Risk: Skin Cancer Controversies, Sun Safety Secrets, and Anti-Aging Breakthroughs With Teo Soleymani, MD

#338: How the Sun ACTUALLY Impacts Skin Aging and Cancer Risk: Skin Cancer Controversies, Sun Safety Secrets, and Anti-Aging Breakthroughs With Teo Soleymani, MD

Today, I'm joined by Teo Soleymani, MD—a double board-certified dermatologist, fellowship-trained Mohs and facial reconstructive surgeon, and an expert in all things skin cancer—plus, he's as entertaining as he is knowledgeable. If you've ever wondered whether you should slather on sunscreen religiously, or if embracing more sunlight is actually good for you, we're here to offer the clarity and nuance that's so often missing from the conversation. Listeners of this podcast can receive 15% off of SunPowder when you go to sunpowder.co/discount/NAT15 (it's .co not .com or else you won't find it). What we discuss: Sun exposure: fear vs. benefits debate ... 00:06:38 Genetics vs. sun in driving skin cancer risk ... 00:09:04 Types of skin cancer explained ... 00:10:38 HPV, environmental toxins, and non-UV causes ... 00:22:35 Burning vs. safe sun—practical advice ... 00:21:24 Sunscreen: mineral vs. chemical, what matters ... 00:36:01 Problems with spray sunscreens ... 00:40:45 Melanin, UV damage, and skin aging ... 00:13:40 Melasma: hormones and stubborn pigmentation ... 00:47:19 Estrogen, collagen, and topical supplements ... 00:49:18 Astaxanthin and polypodium—internal sun protection ... 00:56:01 Nicotinamide: strong evidence for cancer prevention ... 01:04:11 Sunpowder supplement: trials and benefits ... 01:07:43 Laser resurfacing and reduced cancer risk ... 01:12:33 Genetics, immune health, and testing limits ... 01:15:31 Where to find Sunpowder + connect with Teo ... 01:18:53 Our Amazing Sponsors: LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 20% off your order. Qualia - Senolytic - Clinically tested formula with 9 plant-based, vegan ingredients designed to help your body clear out zombie cells—so you can feel younger, faster. Visit qualialife.com/nathalie and use promo code NATHALIE to save 15% Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group More from Teo Soleymani: Website: www.californiadermatology.com and https://sunpowder.co/discount/NAT15 Instagram: @teosoleymanimd Instagram: @drinksunpowder

27 Maj 1h 20min

#337: This Tiny Molecule Can Tackle Inflammation & Immune Health - Diving into KPV with Nathalie Niddam

#337: This Tiny Molecule Can Tackle Inflammation & Immune Health - Diving into KPV with Nathalie Niddam

In this special solo episode, it's just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I'm shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties. What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00 Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That's crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

23 Maj 32min

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