Part 32 - Stephan Guyenet, PhD on the Brain Controlling Body Fatness, Your Food Environment, and Low Carb Controversy

Part 32 - Stephan Guyenet, PhD on the Brain Controlling Body Fatness, Your Food Environment, and Low Carb Controversy

Today we're talking to Stephan Guyenet who has a degree in biochemistry and a PhD in neuroscience. He's spent over 12 years in the neuroscience research world studying neurodegenerative disease and the neuroscience of body fatness. He wrote a great book called The Hungry Brain, speaks at conferences, is a Senior Fellow at GiveWell and scientific reviewer for the Examine.com Research Digest.

He is definitely not a low carb person which is why I had him on. He has a lot of great ideas and is a great mind in the space of nutrition. It was very interesting to hear him talk about all the great benefits he did see when he ate a low carb diet 11 years ago. Make sure to listen until the end when he talks about this.

He has some problems with certain people and aspects of the low carb community and is going on Joe Rogan's podcast soon to debate Gary Taubes on his views of the Carbohydrate Insulin theory of obesity and sugar being uniquely toxic

We had some disagreement on the recommended daily allowance of nutrients - he thinks what's recommended is all you need and getting more than that is pointless. I think this is wrong. I think he's basing it on studies of worthless, non-bioavailable vitamin C pills that in excess do nothing. So in that - I agree. I don't think there's any benefit to popping a bunch of these and think we're going to cure a cold. I do know that our ancestors got estimates of 10-20 times the amount of nutrients we get today, so there's a lot more to this discussion that we didn't have time to get into.

We also disagreed on fiber which led to some carnivore talk. He got some things wrong about the member of the Grateful Dead who was a carnivore. He said he died at a young age of a heart attack. I looked into it and it turns out he was carnivore for 48 years and was in excellent health and died in a car accident at 72.

He also says we don't have longterm studies on the safety of low carb diets at the end. This isn't exactly true and furthermore, we have hundreds of thousands of years of human populations living on low carb diets to prove its safety and efficacy. He additionally mentions the low carb community makes crazy claims that aren't based on science. I'm not sure what he's referring to. Not everything can be measured anyway. If tens of thousands of people report to their doctor they aren't hungry anymore, their energy is stable, their brain is working better, they aren't addicted to sugar, they finally have control of their food intake, etc. then this is some great clinical observations and patient anecdotes that add up to a lot.

I think everyone has their own ideas about things and collects info to support their opinion. It's only natural, and I'm sure I'm doing it to, even though I'm trying not to. Everyone has to be in their camp and collect data and narratives to support their theories. He seemed to do this as you'll see throughout the episode.

I agreed with a lot of his points though, especially that humans didn't evolve to eat based on tracking macros and calories and using an excel spreadsheet to figure out what to eat. He's doing great work and looking at this from a different angle which is important. A lot of interesting stuff here so let's get to it. But first I gotta mention the Food Lies film which is in the last stretch of crowdfunding on Indiegogo. We really need your help to finish it. We have a bunch of cool perks like the Eat Meat T-shirt, the movie poster, bonus features, and more. Find it through FoodLies.org or by clicking through this link in the show notes. I really appreciate it - and now here's Stephan Guyenet.

http://indiegogo.com/projects/food-lies-post

Show Notes

  • I'm obsessed with why we get fat and what to do about it and you've been researching this for a long time
  • Why the brain is the most important place to focus on
  • The brain regulates how much we eat, our food choices, and our exercise
  • There's also non conscious processes the brain regulates that influence caloric expenditure, etc.
  • We also study the human genome to find how that plays a role in body fatness
  • When it comes to body weight, the genes that relate the most are in the brain
  • Nobody wants to overeat, but we end up doing it anyway
  • We need to look at our past to understand why we are wired to seek excess calories
  • Animals and hunter gatherers we've studied follow the Optimum Foraging Theory when they acquire food. It's all about the calories per the amount of effort
  • Because we were eating whole foods from nature, if we got enough calories, we by default we're getting all the vitamins and minerals needed
  • They didn't have white flour, sugar, or refined oils
  • We only have receptors for fat, sugar, salt, and glutamate
  • Apparently those are the nutrients that natural selection cared about most to create reward systems for
  • The Hadza people went mainly for meat, tubers, and honey and didn't go for leafy greens
  • The brain is motivated to pursue calorie containing foods, not vitamins and minerals
  • Combining bliss points make certain foods almost irresistible
  • You need to control your food environment
  • Not only don't have it sitting out so you can see certain foods, don't even have them in the house
  • How do genetics play a role? We know it's way more to do with the type of foods eaten
  • About 70% of people in countries like the US are genetically susceptible to become obese when eating the bad diet that exists there. The remaining percent just aren't as susceptible and can get away with it
  • Energy balance while always be a fact, but there's a lot more to it
  • Eat less, move more may work for some people, but it's not how we evolved. It's not a natural way to regulate body weight
  • You can set up a food environment to allow your body to naturally eat the right amount
  • You'd have to be hungry all the time to continue eating processed foods and try to lose weight
  • His definition and thoughts on nutrient density
  • Questioning the necessity of fiber
  • His views on the carnivore diet - he thinks a big factor is becoming lean and it certainly does that
  • He questions if there's long term chronic disease problems that we don't know about
  • Inuit seek some plant matter
  • Sound engineer from the Grateful Dead who was carnivore for 48 years - Stephan said he died of a heart attack at a young age. Turns out he was super healthy and died of a car accident at 72.
  • His book https://justmeat.co/docs/the-bear.pdf
  • They call him "Bear" https://dangerousminds.net/comments/uncle_johns_ham_the_grateful_deads_all-meat_diet
  • Wikipedia on him: https://en.wikipedia.org/wiki/Owsley_Stanley
  • Stephan agrees with what I always say about going to either end of the extreme with super low carb or super low fat you have great benefits
  • He's going on Joe Rogan's podcast to debate Gary Taubes on his views of the Carbohydrate Insulin theory of obesity and sugar being uniquely toxic
  • What happened with Gary Taubes and Dr. Peter Attia's non profit venture NuSI - the Nutritional Science Initiative?
  • What Stephan got wrong in his blog posts
  • Why he thinks Gary Taubes is wrong and what is the evidence
  • He doesn't like the fact that Gary is calling out scientists
  • Exercise and weight loss
  • The model of obesity he subscribes to is that it's all regulated by the brain
  • Homeostatic regulation - hypothalamus controls body fatness like a thermostat
  • The hormone leptin sends feedback to your brain regarding body fat levels
  • Personal fat threshold, how someone can be skinny on the outside but fat on the inside, people can be obese but metabolically healthy, and insulin as a dam holding back fat in the cells
  • He doesn't think that eating an insulin lowering diet like low carb allows you to lose weight because of the lowered insulin
  • He thinks low carb diets and low fat diets work merely because you're taking away the extreme motivation to overeat the foods, AKA hyperplatability
  • Potato hack
  • Metabolic flexibility
  • He thinks being metabolically inflexible is more a sign of insulin resistance than anything
  • He eats about 50% carb, 18% protein, 32% fat
  • He ate a low carb diet after reading Taubes' book Good Calories, Bad Calories 11 years ago
  • He said it was about the same but one benefit was that he wasn't tied to meal times. Eating high carb he definitely knew when it was time to eat. Easier to fast
  • He was easily doing 24 hour fasts. Now on high carb it's way harder and he experiences brain fog
  • Why are low carb diets so maligned in the mainstream media and medical system?
  • What are his solutions for fixing the nation's health problems?
  • His book The Hungry Brain http://www.stephanguyenet.com/thehungrybrain/
  • His website http://www.stephanguyenet.com
  • His Twitter https://twitter.com/whsource

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

Theme music by https://kylewardmusic.com/

Avsnitt(233)

Part 153 - Dr. Michael Ruscio on All Things Gut Health

Part 153 - Dr. Michael Ruscio on All Things Gut Health

I had a great talk with Dr. Michael Ruscio today on all things gut health! Dr. Ruscio is Doctor of Natural Medicine, Doctor of Chiropractic, clinical researcher and author [1, 2]. His work has been published in peer-reviewed medical journals and he is a committee member of the Naturopathic Board of Gastroenterology research division. His high quality probiotics: https://store.drruscio.com/?rfsn=6444749.3a233de

30 Mars 20221h 10min

Part 152 - Josh Trent on the 5th Pillar of Health

Part 152 - Josh Trent on the 5th Pillar of Health

I usually talk about the 4 pillars of health which I focus on most - diet, sleep, a form of exercise, and sun/outdoors. Josh has been studying what I'm calling the 5th pillar which is the mind/body/spirit stuff that includes stress, breathing, emotional intelligence, etc. I had a great time recording this with him at his home in Austin. We did an hour in the sauna and a cold plunge afterwards!   Josh Trent is the Founder of Wellness Force Media, host of the Wellness + Wisdom Podcast and the creator of the BREATHE a Breath & Wellness Program.   Josh has spent the past 19+ years as a trainer, researcher, and facilitator discovering the physical and emotional intelligence for humans to thrive in our modern world.   Josh and Wellness Force Media Mission is to help humans heal mental, emotional and physical health through podcasts, programs, and a global community that believes in optimizing our potential to live life well.   Josh has dedicated his life to supporting humanity coming together as one.   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org     SHOW NOTES [1:28] - Josh's Background and journey to Wellness Force  [8:15] - Brian's asks Josh to help us understand the spiritual, mental and emotional side of well-being  [22:00] - The Art, Science and Technique  of Breathwork [35:16] - How Past Trauma and Breathwork are related [44:45] - Tips for better breathing posture  [50:30] - The Beginning, Middle and End of Breathwork [57:00] - Looking at Breathwork through an Ancestral Lense [1:01:10] - Josh and Brian's thought son Psychedelics [1:10:00] - The trap of being uncomfortable in our modern life [1:15:45] - What the BREATHE: Breathe and Wellness program and Why Breathwork is so powerful to Josh   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

24 Mars 20221h 29min

Part 151 - Dr. Nick Nwabuaze (The Fittest Doc) Practical Strategies to Improve your Health & Body

Part 151 - Dr. Nick Nwabuaze (The Fittest Doc) Practical Strategies to Improve your Health & Body

Dr. Nwabueze is a board-certified Family Medicine physician who focuses on helping his patients fix the root cause of their stress and poor health. He completed medical school at the Ohio State University College of Medicine and finished his internship and residency at Adventist Hinsdale Hospital in Illinois. He currently uses a mix of resistance training, nutrition coaching, and lifestyle management to form long term relationships with his clients, improving their overall health and happiness through Steady MD, using the Direct Primary Care modality. Find him on Instagram and other social media platforms @thefittestdoc GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDEhttp://sapien.org SHOW NOTES [1:45] - Dr. Nick's Background and Beginning [5:52] - Brian and Nick's thoughts on "Movement is Medicine" [10:50] - How Movement plays into Fat Loss [19:45] - How everything that we put our body through (food, exercise, work) is all stress and how we hormetically get stronger and fitter long-term [23:30] - How and why you should measure Body Composition [32:30] - Brian and Nick's Workout Routines [43:25] - Nick's Mindset on Diet and Nutrition [51:25] - How Dr. Nick works though obesity, obese clients, and mainstream views around obesity [1:21:00] - How Dr. Nick practices medicine with SteadyMD and why he loves it Reach Nick here on SteadyMD GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDEhttp://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg http://youtube.com/c/foodlies

4 Mars 20221h 30min

Part 150 - Richard Perkins on the True Diet of Our Ancestors and Replicating this in Sweden

Part 150 - Richard Perkins on the True Diet of Our Ancestors and Replicating this in Sweden

Richard Perkins is a worldwide leader in the regenerative agriculture space, an author, educator, and farmer. He lives in Sweden with his family on a holistically managed and integrated farm producing a variety of animal and plant foods for his family and community. His practices have taught him how humans must have provided food for themselves for the lion's share of history. From his decades of experience combined with the scientific literature and other accounts around the world, it's apparent they were eating locally & seasonally and relying on nose to tail animal nutrition for the majority of their calories. Please enjoy this episode! GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

1 Mars 20221h 33min

Part 149 - Chris Masterjohn, PhD on Analyzing the Hidden Data You're Not Hearing About

Part 149 - Chris Masterjohn, PhD on Analyzing the Hidden Data You're Not Hearing About

23 Feb 20221h 25min

Part 148 - Dr. Chris Palmer on Incredible Cases of Diet & Lifestyle Reversing Depression, Bipolar, and Schizophrenia

Part 148 - Dr. Chris Palmer on Incredible Cases of Diet & Lifestyle Reversing Depression, Bipolar, and Schizophrenia

In this episode, I had a wonderful conversation with Dr. Chris Palmer who uses diet and lifestyle changes to improve the lives of people suffering from mental and metabolic illness. As you'll learn in the show, there is a metabolic component of many mental health conditions.   Dr. Palmer has been exploring dietary changes, like the ketogenic diet, as treatment for conditions such as schizophrenia, bipolar disorder, and depression. He shares some amazing and inspiring stories that need to be shared with the world if we want to see meaningful changes to our medical system!   Dr. Palmer has been involved in psychiatric research for over 23 years. He received his medical degree from Washington University School of Medicine. He did his internship and psychiatry residency at McLean Hospital, Massachusetts General Hospital, and Harvard Medical School. He is currently the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School.   He has been pioneering the use of the ketogenic diet as a treatment for psychiatric disorders. This is an evidence-based treatment for epilepsy, and epilepsy treatments are commonly used in psychiatry. Additionally, the ketogenic diet has profound effects on brain metabolism that may correct some of the metabolic abnormalities often found in people with mental disorders. He is working with researchers from around the world to assess the effectiveness of this treatment in real people and better understand its mechanisms of action.   Check out his website! - https://www.chrispalmermd.com   DISCLAIMER: The opinions and information provided here by Dr. Chris Palmer and Brian Sanders are not to be taken as medical advice.     SHOW NOTES [3:30] The ketogenic diet and alcoholism [10:30] The ketogenic diet is an evidence-based treatment for epilepsy [13:40] Dr. Chris Palmer's background and personal story [21:40] Why diet works when other treatments fail [26:40] Long-standing psychiatric symptoms resolving with Keto [33:10] Metabolic flexibility and mental health [37:00] Why there's no one-size-fits-all diet [40:40] What happens when patients return to their old habits? [46:00] Treating epilepsy and bipolar disorder with keto [53:40] Mental disorders are metabolic disorders of the brain [57:40] Regular exercise is important, but not enough [1:01:40] Why isn't exercise enough for some people? [1:07:40] Depression is skyrocketing – can diet sometimes help? [1:13:00] Depression and comfort foods [1:15:40] Dr. Chris Palmer is working on a book!   GET THE MEAT! http://NosetoTail.org  GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org  Follow along: http://twitter.com/FoodLiesOrg  http://instagram.com/food.lies  http://facebook.com/FoodLiesOrg

22 Dec 20211h 20min

Part 147 - An Insider's Look at Public Health Guidelines and the Medical System - Dr. Chris Dan and Dr. Gary Shlifer

Part 147 - An Insider's Look at Public Health Guidelines and the Medical System - Dr. Chris Dan and Dr. Gary Shlifer

In this episode, I sat down with Dr. Chris Dan and Dr. Gary Shlifer to talk about the shortcomings of the medical system and current public health guidelines. Both of them have experienced frustration with the modern medical system, especially as it relates to the pandemic and the prevention of chronic disease.   We discuss the chaotic and confusing public health guidelines over the past 2 years as well as the importance of metabolic health on our immune health. Dr. Chris Dan exposes some of the biggest problems with the healthcare system and explains why he left the hospital.   Dr. Chris Dan is currently a family medicine board certified physician who worked as a full time Hospitalist in Los Angeles County for the past four years. He completed his undergraduate degree at UCI and studied medicine at Western University of Health Sciences in Pomona. During his time as an inpatient physician, he saw the shortcomings of the current medical system in prevention of chronic disease and will be moving on to work outpatient with a focus on returning people to metabolic health.   Dr. Gary Shlifer is a board-certified internal medicine physician specializing in preventative care, nutrition/metabolism and anti-aging medicine. Dr. Gary brings his robust experienced with hospital inpatient medicine to his outpatient primary care practice in order to help prevent and cure disease in his patients. He is the founder of Evolve Healthcare in Los Angeles, a multi-specialty integrative medicine clinic focused on disease prevention and lifestyle optimization.     SHOW NOTES [7:20] Dr. Chris Dan's background [10:50] The problems with inpatient medicine [17:10] Why the medical system is a numbers game [23:10] Chaotic & confusing pandemic guidelines [27:10] Why generic drugs are discouraged [32:40] How COVID affected healthcare workers [39:40] The corporate & bureaucratic structure of healthcare [44:10 Healthcare doesn't make money on healthy people [49:40] The "diabetes diet" in hospitals [54:30] Why Dr. Chris Dan left the hospital [59:50] What's the biggest problem in healthcare? [1:03:10] What you should do if you don't want to burden the healthcare system   GET THE MEAT! http://NosetoTail.org  GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org  Follow along: http://twitter.com/FoodLiesOrg  http://instagram.com/food.lies  http://facebook.com/FoodLiesOrg

15 Dec 20211h 9min

Part 146 - How a Norwegian Farmer Changed the Mind of the World's Most Powerful Anti-Meat Activist

Part 146 - How a Norwegian Farmer Changed the Mind of the World's Most Powerful Anti-Meat Activist

Today's episode features a farmer from Norway named Raymund. Raymund is truly a hero because he hosted Dr. Gunhild A. Stordalen at his farm where he educated her on the benefits that animal agriculture can have on our ecosystem. Dr. Gunhild A. Stordalen is a very well known environmental activist and the founder of EAT which recommends a mere 14 grams of red meat per day as part of a "Planetary Health Diet."   As you'll learn in this episode, Raymund convinced her that meat and animal agriculture are a sustainable and essential part of our food system. Throughout this episode, we discuss many of the problems with our modern food system. In fact, Raymund runs a decentralized food system in Norway called REKO which connects farmers directly to customers. We are hoping to bring something similar to Texas and eventually all over the United States.   Learn more at https://www.sovereignhumans.org     SHOW NOTES: [6:15] How Raymund knows Gunhild Stordalen of EAT Lancet [10:30] Meat is required for a healthy diet and planet [15:00] What Raymund told Gunhild Stordalen [20:35] Problems with the Planetary Diet [26:40] How consumerism is wasteful [30:20] Why big corporations hate a decentralized food system [37:00] Our changing food & spending habits [40:00] The industrial farming of salmon [43:50] Why raising pigs is so difficult [47:00] How Raymond built a sustainable farm [53:30] Why you should spend more on food and less elsewhere [56:30] Everyone needs their own farmer, not their own doctor [1:01:20] How cities destroyed our food system [1:06:30] Our modern food system is a failed experiment [1:12:45] Vote with your dollar by eating local   GET THE MEAT! http://NosetoTail.org  GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org    Follow along: http://twitter.com/FoodLiesOrg  http://instagram.com/food.lies  http://facebook.com/FoodLiesOrg

8 Dec 20211h 16min

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