Part 32 - Stephan Guyenet, PhD on the Brain Controlling Body Fatness, Your Food Environment, and Low Carb Controversy

Part 32 - Stephan Guyenet, PhD on the Brain Controlling Body Fatness, Your Food Environment, and Low Carb Controversy

Today we're talking to Stephan Guyenet who has a degree in biochemistry and a PhD in neuroscience. He's spent over 12 years in the neuroscience research world studying neurodegenerative disease and the neuroscience of body fatness. He wrote a great book called The Hungry Brain, speaks at conferences, is a Senior Fellow at GiveWell and scientific reviewer for the Examine.com Research Digest.

He is definitely not a low carb person which is why I had him on. He has a lot of great ideas and is a great mind in the space of nutrition. It was very interesting to hear him talk about all the great benefits he did see when he ate a low carb diet 11 years ago. Make sure to listen until the end when he talks about this.

He has some problems with certain people and aspects of the low carb community and is going on Joe Rogan's podcast soon to debate Gary Taubes on his views of the Carbohydrate Insulin theory of obesity and sugar being uniquely toxic

We had some disagreement on the recommended daily allowance of nutrients - he thinks what's recommended is all you need and getting more than that is pointless. I think this is wrong. I think he's basing it on studies of worthless, non-bioavailable vitamin C pills that in excess do nothing. So in that - I agree. I don't think there's any benefit to popping a bunch of these and think we're going to cure a cold. I do know that our ancestors got estimates of 10-20 times the amount of nutrients we get today, so there's a lot more to this discussion that we didn't have time to get into.

We also disagreed on fiber which led to some carnivore talk. He got some things wrong about the member of the Grateful Dead who was a carnivore. He said he died at a young age of a heart attack. I looked into it and it turns out he was carnivore for 48 years and was in excellent health and died in a car accident at 72.

He also says we don't have longterm studies on the safety of low carb diets at the end. This isn't exactly true and furthermore, we have hundreds of thousands of years of human populations living on low carb diets to prove its safety and efficacy. He additionally mentions the low carb community makes crazy claims that aren't based on science. I'm not sure what he's referring to. Not everything can be measured anyway. If tens of thousands of people report to their doctor they aren't hungry anymore, their energy is stable, their brain is working better, they aren't addicted to sugar, they finally have control of their food intake, etc. then this is some great clinical observations and patient anecdotes that add up to a lot.

I think everyone has their own ideas about things and collects info to support their opinion. It's only natural, and I'm sure I'm doing it to, even though I'm trying not to. Everyone has to be in their camp and collect data and narratives to support their theories. He seemed to do this as you'll see throughout the episode.

I agreed with a lot of his points though, especially that humans didn't evolve to eat based on tracking macros and calories and using an excel spreadsheet to figure out what to eat. He's doing great work and looking at this from a different angle which is important. A lot of interesting stuff here so let's get to it. But first I gotta mention the Food Lies film which is in the last stretch of crowdfunding on Indiegogo. We really need your help to finish it. We have a bunch of cool perks like the Eat Meat T-shirt, the movie poster, bonus features, and more. Find it through FoodLies.org or by clicking through this link in the show notes. I really appreciate it - and now here's Stephan Guyenet.

http://indiegogo.com/projects/food-lies-post

Show Notes

  • I'm obsessed with why we get fat and what to do about it and you've been researching this for a long time
  • Why the brain is the most important place to focus on
  • The brain regulates how much we eat, our food choices, and our exercise
  • There's also non conscious processes the brain regulates that influence caloric expenditure, etc.
  • We also study the human genome to find how that plays a role in body fatness
  • When it comes to body weight, the genes that relate the most are in the brain
  • Nobody wants to overeat, but we end up doing it anyway
  • We need to look at our past to understand why we are wired to seek excess calories
  • Animals and hunter gatherers we've studied follow the Optimum Foraging Theory when they acquire food. It's all about the calories per the amount of effort
  • Because we were eating whole foods from nature, if we got enough calories, we by default we're getting all the vitamins and minerals needed
  • They didn't have white flour, sugar, or refined oils
  • We only have receptors for fat, sugar, salt, and glutamate
  • Apparently those are the nutrients that natural selection cared about most to create reward systems for
  • The Hadza people went mainly for meat, tubers, and honey and didn't go for leafy greens
  • The brain is motivated to pursue calorie containing foods, not vitamins and minerals
  • Combining bliss points make certain foods almost irresistible
  • You need to control your food environment
  • Not only don't have it sitting out so you can see certain foods, don't even have them in the house
  • How do genetics play a role? We know it's way more to do with the type of foods eaten
  • About 70% of people in countries like the US are genetically susceptible to become obese when eating the bad diet that exists there. The remaining percent just aren't as susceptible and can get away with it
  • Energy balance while always be a fact, but there's a lot more to it
  • Eat less, move more may work for some people, but it's not how we evolved. It's not a natural way to regulate body weight
  • You can set up a food environment to allow your body to naturally eat the right amount
  • You'd have to be hungry all the time to continue eating processed foods and try to lose weight
  • His definition and thoughts on nutrient density
  • Questioning the necessity of fiber
  • His views on the carnivore diet - he thinks a big factor is becoming lean and it certainly does that
  • He questions if there's long term chronic disease problems that we don't know about
  • Inuit seek some plant matter
  • Sound engineer from the Grateful Dead who was carnivore for 48 years - Stephan said he died of a heart attack at a young age. Turns out he was super healthy and died of a car accident at 72.
  • His book https://justmeat.co/docs/the-bear.pdf
  • They call him "Bear" https://dangerousminds.net/comments/uncle_johns_ham_the_grateful_deads_all-meat_diet
  • Wikipedia on him: https://en.wikipedia.org/wiki/Owsley_Stanley
  • Stephan agrees with what I always say about going to either end of the extreme with super low carb or super low fat you have great benefits
  • He's going on Joe Rogan's podcast to debate Gary Taubes on his views of the Carbohydrate Insulin theory of obesity and sugar being uniquely toxic
  • What happened with Gary Taubes and Dr. Peter Attia's non profit venture NuSI - the Nutritional Science Initiative?
  • What Stephan got wrong in his blog posts
  • Why he thinks Gary Taubes is wrong and what is the evidence
  • He doesn't like the fact that Gary is calling out scientists
  • Exercise and weight loss
  • The model of obesity he subscribes to is that it's all regulated by the brain
  • Homeostatic regulation - hypothalamus controls body fatness like a thermostat
  • The hormone leptin sends feedback to your brain regarding body fat levels
  • Personal fat threshold, how someone can be skinny on the outside but fat on the inside, people can be obese but metabolically healthy, and insulin as a dam holding back fat in the cells
  • He doesn't think that eating an insulin lowering diet like low carb allows you to lose weight because of the lowered insulin
  • He thinks low carb diets and low fat diets work merely because you're taking away the extreme motivation to overeat the foods, AKA hyperplatability
  • Potato hack
  • Metabolic flexibility
  • He thinks being metabolically inflexible is more a sign of insulin resistance than anything
  • He eats about 50% carb, 18% protein, 32% fat
  • He ate a low carb diet after reading Taubes' book Good Calories, Bad Calories 11 years ago
  • He said it was about the same but one benefit was that he wasn't tied to meal times. Eating high carb he definitely knew when it was time to eat. Easier to fast
  • He was easily doing 24 hour fasts. Now on high carb it's way harder and he experiences brain fog
  • Why are low carb diets so maligned in the mainstream media and medical system?
  • What are his solutions for fixing the nation's health problems?
  • His book The Hungry Brain http://www.stephanguyenet.com/thehungrybrain/
  • His website http://www.stephanguyenet.com
  • His Twitter https://twitter.com/whsource

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

Theme music by https://kylewardmusic.com/

Avsnitt(233)

Part 177 - Ty Beal on the Top Nutrient Dense Food List & Global Nutrition Solutions

Part 177 - Ty Beal on the Top Nutrient Dense Food List & Global Nutrition Solutions

Ty Beal is based in Washington DC as a Research Advisor on the Knowledge Leadership team at the Global Alliance for Improved Nutrition (GAIN). In this role, he supports programmes, research, evaluation, and dissemination of knowledge to stakeholders. He has extensive experience examining sustainable food systems, diet quality, food affordability, food supplies, micronutrient deficiencies, child growth and development, noncommunicable diseases, and global health. He obtained a PhD in Geography with emphasis in Global Nutrition from the University of California, Davis, where he was a National Science Foundation Graduate Research Fellow.   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES: 00:00- A little bit about who Ty is 01:40- Why should we care about nutrients? 06:30- Ty's studies and the 6 most important nutrients 13:40- The importance of bioavailability and anti nutrients 20:50- Why we should stop fearing animal foods 23:00- Astonishing worldwide deficiency statistics 31:15- What even is a whole grain? 32:40- The food compass 42:15- Nutrient intake and stunted growth 47:00- Discussion on the food environment 52:50- The environmental issue and the future of health 1:00:00- The Eat Lancet diet 1:08:00- The spectrum of healthy diets 1:09:15- Should you eat leafy greens? 1:19:00- Where to find Ty   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

30 Nov 20221h 27min

Part 176 - Decentralization Solving Many of the World's Biggest Problems w/ Matt Grebosky & Brian Sanders

Part 176 - Decentralization Solving Many of the World's Biggest Problems w/ Matt Grebosky & Brian Sanders

This is a special episode on decentralizing the main areas of society and your life to solve some of the biggest problems we're facing. The big systems are working against us. Most aspects of society are being centralized by corporations and governments at the expense of the individual. For personal health & wealth you should be decentralizing your: - Food/food production - Finances - Health(care) - Community - Education Listen for some practical solutions! Brian Sanders is the filmmaker behind the Food Lies documentary, host of the top 5 nutrition podcast Peak Human, and an international speaker. He graduated from UCLA with a degree in Mechanical Engineering. He works as a Health Coach at Evolve Healthcare and co-founded the health education company Sapien. He also works to spread the awareness of regenerative agriculture and increase access to well-raised animal products through his company Nose to Tail. Matt Grebosky is a CHEK Practitioner, Holistic Health Coach and Head of Operations at Nose to Tail and The Sapien Center. Specializing in ancestral health, nutrition and living, Matt uses a blend of modern science and traditional practices to offer advice on how to approach living a healthy and happy life. Matt studied Holistic Lifestyle and Exercise Coaching at the CHEK Institute in Vista, California after graduating from Penn State University with a degree in Kinesiology. Coaching in various different formats for several years he then transformed his passion for ancestral health to start working for Nose to Tail and eventually The Sapien Center. Follow Matt on Instagram MattGrebosky.com

15 Nov 20221h 11min

Part 175 - Chris Kresser on Why The World is Unhealthy (And What To Do About It)

Part 175 - Chris Kresser on Why The World is Unhealthy (And What To Do About It)

Chris Kresser, M.S., L.Ac., is a globally-renowned expert, clinician, and educator in the fields of Functional Medicine and ancestral health and the New York Times bestselling author of The Paleo Cure and Unconventional Medicine. He was named one of the 100 most influential people in health and fitness by Greatist.com and has appeared as a featured guest on Dr. Oz, Time, The Atlantic, NPR, Fox & Friends, and other national media outlets. ChrisKresser.com   Chris co-founded and co-directed the California Center for Functional Medicine, one of the largest Functional Medicine clinics on the west coast. Throughout his 15-year career he has helped hundreds of patients reverse chronic disease and recover their health and vitality.   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES   02:40 - Barriers to proper healthcare consulting 03:50 - How the modern food system is causing Nutrient deficiencies.  05:45 - Why eating healthy might not be enough to combat nutrient deficiencies 11:00 - Can we get enough nutrients in the modern environment?  14:30 - Chris's thoughts on hair mineral analysis testing.  16:45 - The problem with vegan and carnivore diets. 21:50 - Nutrient degradation overtime 25:40- Chris's opinion on oxalates and plant toxins.  28:20- The benefits of eating seasonally 34:50 - Humans have an innate drive to eat certain foods.  39:50 - The nutrient leverage hypothesis. 45:15 - Why we don't know about our nutrient deficiencies. 48:00 - The best ways to maximize the nutrient density of our diets. 57:05 - The issues with the dietary guidelines 59:15 -  Chris's opinion on phytonutrients 1:02:30 - Many diets can work to elicit good health. 1:06:30- The height studies 1:13:40 - Practical way to optimize your nutrient status.  1:22:30 - Where to find Chris Kresser   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

9 Nov 20221h 29min

Part 174 - Leigh Erin Connealy, MD on How to Eat to Save Your Life

Part 174 - Leigh Erin Connealy, MD on How to Eat to Save Your Life

Leigh Erin Connealy, M.D. is a prominent leader in the Integrative & Functional Medicine medical field. She is the Medical Director of two amazing clinics "The Cancer Center For Healing" & "Center For New Medicine". The clinics have become the largest Integrative Medical Clinic in North America and visited by patients from all over the world with 47,000 patients and growing. She's authored 2 books including "The Cancer Revolution" and was named one of the top 50 functional & integrative doctors in the country in 2017. https://www.connealymd.com/ GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES 0:00- Welcome back Dr. Connealy! 00:06- A picture of what life at Dr. Connealy's clinic looks like 2:03 - How to screen for cancer in the healthiest way. 9:28- The variables cancer patients need to pay attention to. 11:24- A brief aside about the health of the population 12:30- Important practices that Dr.Connealy recommends 19:30 - Dr. Connealy's approach to stress management 21:55 - Why stress is such a big issue in the modern society 27:00 - The last 10 % can make a big difference 32:25- How Dr. Connealy and her team eats. 41:45 - Why proper screening is so important. 49:40- The importance of the internal terrain. GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

2 Nov 202259min

Part 173 - Dr. Leigh Erin Connealy, MD on Treating Cancer with Diet & Lifestyle

Part 173 - Dr. Leigh Erin Connealy, MD on Treating Cancer with Diet & Lifestyle

Leigh Erin Connealy, M.D. is a prominent leader in the Integrative & Functional Medicine medical field. She is the Medical Director of two amazing clinics "The Cancer Center For Healing" & "Center For New Medicine". The clinics have become the largest Integrative Medical Clinic in North America and visited by patients from all over the world with 47,000 patients and growing. She's authored 2 books including "The Cancer Revolution" and was named one of the top 50 functional & integrative doctors in the country in 2017. https://www.connealymd.com/ GET THE MEAT http://NosetoTail.org JOIN THE NEWSLETTER http://sapien.org SHOW NOTES 06:15 -How Brian found Dr. Connealy 06:53 -What Dr. Connealy does 31:45 -Why health starts at the mitochondria 41:30 -The mindset 42:10 -Find Dr. Connealy GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

26 Okt 202243min

Part 172 - Dan Kittredge on the Amazing Power of Nutrient Density and How to Measure It

Part 172 - Dan Kittredge on the Amazing Power of Nutrient Density and How to Measure It

Dan Kittredge has been an organic farmer for more than 30 years and is the founder and executive director of the Bionutrient Food Association (BFA), a non-profit whose mission is to "increase quality in the food supply." Known as one of the leading proponents of "nutrient density," Dan works to demonstrate the connections between soil health, plant health, and human health. Out of these efforts was born the Real Food Campaign, now the Bionutrient Institute, which has engineered a prototype of a hand-held consumer spectrometer designed to test nutrient density at point of purchase. Via the Bionutrient Meter, the goal is to empower consumers to choose for nutrient quality and thereby leverage economic incentives to drive full system regeneration. https://www.bionutrientinstitute.org/meetdan BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman SHOW NOTES 00:00 - Dan's upcoming events 00:45- Why should we care about nutrient density? 1:25 - Weston A. Price 1:50 - Why are some foods more nutrient dense than others? 4:08 - Dan's background. 7:02 - The Bio nutrient association. 8:00 - Your body is made up of the foods that you are eating. 9:50 - Nutrient density starts in the soil 14:40 - The modern food environment is blunting our natural instincts for nutrients. 18:40 - Dan's mission to inform the public about nutrient density 33:30 - The sick care system 36:30 - What is spectroscopy? 44:00- Dan's vision for the future 48:00 - The beef project, and how the plants are affecting the quality of the meat. BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

19 Okt 20221h 8min

Part 171 - All my Health Tips/Thoughts in One Place! (Brian Sanders interviewed by Courtney Swan)

Part 171 - All my Health Tips/Thoughts in One Place! (Brian Sanders interviewed by Courtney Swan)

This week I'm posting Courtney Swan interviewing me!   Her site: https://www.realfoodology.com     GET THE MEAT http://NosetoTail.org      Topics Discussed: Pre-diabetes Insulin resistance Food pyramid What we got wrong about red meat Veganism Carnivorism Grains How grains changed the way humans evolved History of processed foods Food marketing Climate change How agriculture kills animals too Energy balance consortium Importance of building muscle Healthy state of some indigenous tribes The Maasai people Seed oils Satiety   GET THE MEAT http://NosetoTail.org    Follow along: http://twitter.com/FoodLiesOrg  http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

5 Okt 20221h 10min

Part 170 - Dr. William Davis on the Simple Diet Switches to Change Your Life & Your Gut Health

Part 170 - Dr. William Davis on the Simple Diet Switches to Change Your Life & Your Gut Health

Dr. William or Bill Davis is a cardiologist, a New York Times #1 bestselling author of the Wheat Belly book series and is the Medical Director and founder of the Undoctored program including the Undoctored Inner Circle, where he helps individuals take back control of their gut, health and lifestyle. Dr. Bill is also the Chief Medical Officer and co-founder of Realize Therapeutics Corp. that is developing innovative solutions for the disrupted human microbiome and author of the book Super Gut GET THE MEAT http://NosetoTail.org SHOW NOTES: [0:25] - Dr. Bill's thoughts on vegetarianism and veganism and the common nutrient deficiencies that accompany the diets [5:00] - Dr. Bill's background, Why he is so outspoken about nutrition and heart health, and the birth of his book Wheat Belly [16:00] - How humans amplified the destructive nature of Grains, Wheat and Soy [28:00] - Modern gut health, measuring microbiota and his book Super Gut [38:05] - Dr. Bill's take on Keto/Carnivore/Low FODMAP diets and their effects on the gut microbiome [45:40] - SIBO, Pre and Probiotics, and creating your own probiotic regiment based on your goals [59:00] - The Hadza, Ancestral diet and Moderns toxins [1:12:20] - Solutions from Dr. Bill to Improve health and your gut GET THE MEAT http://NosetoTail.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

28 Sep 20221h 27min

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