Part 35 - Dr. Thomas Seyfried on Cancer as a Metabolic Disease, More Effective Therapies, and Treating it Without Toxicity

Part 35 - Dr. Thomas Seyfried on Cancer as a Metabolic Disease, More Effective Therapies, and Treating it Without Toxicity

Dr. Thomas Seyfried is a Professor of Biology at Boston College, and received his Ph.D. in Genetics and Biochemistry from the University of Illinois. He then worked as an assistant professor in the neurology department at the Yale school of medicine. He has over 180 peer-reviewed publications and is author of the book, Cancer as a Metabolic Disease. He recently received a Lifetime Achievement Award from the Academy of Complimentary and Integrative Medicine.

I got a chance to meet and interview him at the Metabolic Health Summit earlier this year. You'll notice we did this podcast shortly after the Super Bowl. In case people aren't familiar with American football the New England Patriots had just beaten the LA Rams.

I hope people look up the paper he recently published that we mention and watch his presentation I linked to in the show notes and go deeper on this topic. It's very surprising to learn of this completely new view on cancer if you haven't heard of it before. This really shouldn't be very surprising to anyone, however, because of course our modern diet and lifestyle would have the biggest effect on the rising cancer rates. And of course fixing these things would also be a major part of the treatment. He's really doing legendary work. So without further ado, here's professor Seyfried.

You can still preorder a copy of Food Lies on Indiegogo even though our campaign just ended. We still need your support to finish post production.

http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

Show Notes

  • Dr. Thomas Seyfried believes cancer is a metabolic disease, not a genetic disease and explains in simple terms why that is
  • The mitochondria in your cells make energy (ATP)
  • There's 2 types of energy: ancient energy which is a fermentation metabolism which means you can make energy without oxygen, or respiration where you make energy from breathing air
  • Cancer cells ferment - therefore they don't use oxygen
  • Not all cancer cells have genetic mutations, but all cancer cells ferment
  • The mitochondrial metabolic theory says that the organelle that makes energy from respiration is defective, forcing the cell to ferment. When the cell ferments, mutations collect in the nucleus
  • This means the genetic mutations seen in cancer cells come from a downstream effect of disruption of energy metabolism
  • The cancer cell has to consume a large amount of glucose and the amino acid glutamine in order to survive on a fermentation metabolism
  • On the other hand, normal cells use oxygen and very little amounts of glucose
  • This should make sense to a lot of people because they've probably heard cancer cells need a lot of glucose and if you starve them of that they die
  • Have to re-emphasize the fact that the DNA damage comes as a downstream effect
  • Damaged mitochondria, instead of making ATP, make Reactive Oxygen Species (ROS) or oxidative stress (which causes a lot of problems in our body)
  • The oxidative stress also causes damage to the nucleus and the genome
  • The field of cancer research studies effects instead of causes
  • We're not treating cancer by looking at the root cause - it's absurd - how would we ever cure it?
  • This is supported by thousands of experiments and studies
  • Obvious step to treat cancer is to deprive the cancer cells of glucose and glutamine and transition healthy cells into the use of ketones which they can readily use
  • We evolved as a starving creature and convert fatty acids into ketones and usable forms of energy
  • Cancer cells can't use ketones
  • There's no dietary way to restrict glutamine to the cancer cells so drugs have to be used
  • Basically nobody he's heard of is treating it this way
  • If it's so clear this is how cancer works, why has this not reached the mainstream?
  • The Federal government puts out websites saying cancer is genetic, medical schools teach it's genetic, leading cancer clinics tell patients it's genetic
  • Entrenched beliefs continue this. Also funding money is all based around the genetic theory
  • If you look at the mitochondria of any cancer cell under an electron microscope you can easily see the damage to the organelles and mitochondria
  • Cancer is a result of the industrialization as a society
  • Cancer is so rare throughout history or with non-industrialized societies they don't even have the word for it in their language
  • Cancer comes from all kinds of things like pollution, chemicals, radiation, hypoxia, infections, chronic inflammation, even some rare inherited diseases like BRCA1 (but it has to damage the mitochondria)
  • These are all secondary - the root cause is damage to the respiration
  • Obese people have higher rates of cancer and also higher inflammation (measured by C reactive protein)
  • To avoid cancer it's as simple as avoiding diets and lifestyles that risk damage to the mitochondria
  • Metabolic therapies need to at least be options for people
  • Problem is doctors aren't aware of them or aren't trained on them
  • Therapeutic ketosis is a medicine - it's different than just a diet (which is a turn-off to a lot of medical professionals)
  • There's therapeutic weight loss and toxic weight loss
  • Using a suite of therapies to cure cancer including ketogenic metabolic therapy and hyperbaric oxygen therapy
  • Hyperbaric oxygen creates reactive oxygen species that kills cancer cells but healthy cells using ketones are protected from oxidative stress and are fine
  • Burning ketones creates less ROS (which is a good thing) and is why many people without cancer eat a ketogenic diet
  • ROS damages tissues and is why you age
  • He published the glucose-ketone index calculator
  • People need to realize sweets are a treat once in awhile - not an everyday thing
  • The food industry has played into our ancient desires for sweet
  • Otto Warburg studied cancer in the early 1900s
  • He found that cancer cells would grow in an 100% oxygen environment - they continue to ferment and create lactic acid
  • Because their mitochondria are defective they can't switch back to oxidative phosphorylation
  • He recently published a paper filling in the gaps from Otto Warburg's work
  • Missing link was the glutamine that cancer cells can also use
  • Have to pulse the glutamine so the immune system can do it's job and clear out the dead cells
  • He's developed the press-pulse system in his lab to attack tumors strategically
  • Almost there with dosage, timing, and schedule - when done with this will have the pathway to resolution
  • He's having trouble getting funding for this for some reason
  • One problem is people have created separate little communities and foundations around their specific type of cancer even though they all have the common metabolic foundational problem
  • People are going to have to participate in the management of their disease and the culture of the diseases has to change
  • Another problem is the high cost of these standard therapies - people have to pay $400k
  • His paper looking at research conducted on cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941741/
  • If you take a normal cytoplasm and implant a nucleus with a tumor you get normal cells. But if you implant a normal nucleus to a cell with damaged cytoplasm, you get more tumor cells. This shows it's the damaged mitochondria in the cytoplasm, not the DNA in the nucleus
  • The wheelchair doesn't cause your legs to not work
  • Needle biopsies are putting people at risk and are pointless
  • He calls this general misunderstanding of cancer the biggest tragedy in the history of medicine
  • What do critics of his views say? They try to create doubt
  • They rely on private funding and some great organizations supporting this research
  • Travis Christofferson's foundation https://foundationformetaboliccancertherapies.com
  • His book Tripping Over the Truth https://www.amazon.com/Tripping-over-Truth-Overturning-Entrenched/dp/1603587292/
  • Dr. George Yu's foundation https://yufoundation.org
  • Presentation by Dr. Seyfried https://www.youtube.com/watch?v=APwnkpD_BfI&frags=pl%2Cwn
  • Dr. Seyfried's book https://www.amazon.com/Cancer-Metabolic-Disease-Management-Prevention/dp/0470584920/

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

Theme music by https://kylewardmusic.com/

Avsnitt(235)

Part 131 - Cynthia Monteleone on How to Be Fast and Fit Over 40 on Steak

Part 131 - Cynthia Monteleone on How to Be Fast and Fit Over 40 on Steak

CM (Cynthia) Monteleone is a World Champion in the 400m, a mom of 3, and author and a Metabolic Analytics Practitioner. It was no coincidence that when Cynthia decided to become the best in the world, she chose Charles Poliquin to study under. Her mentor shared his knowledge and encouraged her to keep up the fire for learning and achieving. Cynthia gets tremendous results because of her passion: which is to help others thrive. MAM Maui Metabolics grew out of this mission to encourage others to become their own superhero warrior self. When winning the gold, she ran faster at age 43 then she did as a Division I collegiate track athlete! She attributes this to learning how to alter epigenetics to favor delayed aging, healthy biomarkers and exceptional athletic performance. After listening to and consulting on hundreds of client cases, (everyone from Olympians to the neighbor next door) she is adept at reading patterns and using her knowledge and experience to solve health and performance puzzles with easy protocols. She lives in Maui with her husband and 3 children. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES [5:10] Her background and education. [13:40] Her mission with her clients. [16:25] Using carbs over fat for exercise performance. [26:10] Endurance training, gastrointestinal stress and overtraining. [32:40] Running barefoot and the benefits of sprinting. [39:40] Issues with plant based diets. Presence of Bacteria in Spontaneous Achilles Tendon Ruptures Chronic inflammation is a feature of Achilles tendinopathy and rupture [43:40] Prevotella bacteria from carbohydrate consumption. COVID-2019-associated overexpressed Prevotella proteins mediated host-pathogen interactions and their role in coronavirus outbreak Gut microbiota and Covid-19- possible link and implications [46:40] Injuries and plant based diets. [48:50] Red meat and hormone balance. [55:20] The negative connotation of red meat. [59:40] Introduction to Margaret, Cynthia's daughter. [1:18:10] Protein shake trick for mood swings. [1:20:30] Her blood work and her doctor's opinion on it. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

21 Juli 20211h 27min

Part 130 - Dr. Kirk Parsley, MD - Is Sleep the Foundation of Health?

Part 130 - Dr. Kirk Parsley, MD - Is Sleep the Foundation of Health?

Doc Parsley (Dr. Kirk Parsley) served as an Undersea Medical Officer at Naval Special Warfare Group One from June 2009 to January 2013. While there, he led the development and supervised the group's first Sports Medicine Rehabilitation center. He is a former SEAL, and received his Medical Degree from Bethesda, Uniformed Services University of Health Sciences (USUHS) in 2004. Doc Parsley has been a member of the American Academy of Sleep Medicine since 2006 and has served as Naval Special Warfare's expert on Sleep Medicine. In addition, he is certified in hormonal modulation (Age-Management Medicine). After leaving the Navy he went into concierge medicine and consulting. He continues to consult for multiple corporations, and professional athletes/teams. Doc Parsley lectures worldwide on sleep, wellness, and hormonal optimization. Find him at https://docparsley.com Before we jump in I'll give you my disclosures. I take no outside funding or sponsorships for this podcast or any of my work. The only thing supporting it is my company http://NoseToTail.org that I started well after I understood the health benefits of including quality animal foods in our diet. In other words I have no outside interests influencing the information I present and I am not creating this content to sell my products. My foundational belief is that animal foods are healthy so I connected with the best producers around the country to help people purchase them. We raise them humanely and sustainably. We don't use additives or curing agents. Everything is all natural. We use the animals nose to tail. We have products such as primal ground beef that includes liver, heart, kidney, and spleen for all the amazing nutrients and none of the hassle or taste you may not be used to. That's at http://NoseToTail.org We ship boxes straight to you and have free shipping options. We also have biltong if you want grass finished meat on the go. This is a traditional South African meat snack that's air dried, soft, and delicious. We have body care products made from beef tallow and only a couple other natural ingredients. We also have seasonings to go along with these wonderful products and make cooking that much easier. Make a custom box today at http://NoseToTail.org and take advantage of the free shipping options. That's how these interviews are all possible along with all the other content we produce on youtube and social media. Thanks for supporting the ranchers, my other producers, and my team. The other way you can take advantage of this win-win-win situation is at http://Sapien.org where we have the Sapien Tribe. It's a private members community where you get the extended show notes for these podcasts, discounts on NoseToTail products, zoom calls with Dr. Gary and myself, and a lot more. There's also the Sapien Program if you'd like some help making a lifestyle change. Go to http://Sapien.org to find out more. Now onto the show! GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES [4:15] His background and work experience as a Doctor for Navy Seals. [11:00] Sleep drugs and their mechanisms of action. [21:35] A deep dive into sleep cycles. [29:45] The processes that occur when you go to sleep. [39:15] Sleep apnea. [42:45] Decline in performance with loss of sleep. [53:45] Sleep genetics. [1:01:00] We can't cheat nature and evolution. [1:07:55] How to improve deep quality sleep. [1:19:05 Caffeine consumption. [1:27:00] Biphasic sleep and waking up in the middle of the night. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

14 Juli 20211h 34min

Part 129 - Stephanie Seneff, PhD - Is Glyphosate Slowly Killing Us?

Part 129 - Stephanie Seneff, PhD - Is Glyphosate Slowly Killing Us?

Hey friends, thanks for tuning into Peak Human. I'm Brian Sanders, the creator of the much-anticipated Food Lies film. Things are going well with the post production so thank you for your continued support on Indiegogo and your patience. My guest today is Dr. Stephanie Seneff who has been studying the effects of glyphosate for almost 10 years now. She has put together TONS of science about why it's bad for you and the environment, even though it's marketed as safe. Of course Monsanto has led you and regulators to believe this. The tricky part here is that it supposedly doesn't affect human cells, but it does affect all the billions of bacteria in your microbiome and the soil biome. She'll get into all the details in this episode so listen on, my friend! Stephanie Seneff, PhD is a senior research scientist at MIT's Computer Science and Artificial Intelligence Lab. Her new book, Toxic Legacy, explores the harmful effects of the herbicide glyphosate on our health and the environment. Her book is backed by shocking evidence that points the finger at glyphosate as being responsible for many debilitating chronic diseases. While at MIT, she received four degrees: a bachelor's degree in biophysics as well as a M.S., E.E, and a PhD in electrical engineering and computer science. She has also written dozens of peer-reviewed papers on the effects of drugs, nutritional deficiencies, toxic chemicals, and diet on our health. Get her book! https://amzn.to/3hlMYeZ Before we jump in I'll give you my disclosures. I take no outside funding or sponsorships for this podcast or any of my work. The only thing supporting it is my company http://NoseToTail.org that I started well after I understood the health benefits of including quality animal foods in our diet. In other words I have no outside interests influencing the information I present and I am not creating this content to sell my products. My foundational belief is that animal foods are healthy so I connected with the best producers around the country to help people purchase them. We raise them humanely and sustainably. We don't use additives or curing agents. Everything is all natural. We use the animals nose to tail. We have products such as primal ground beef that includes liver, heart, kidney, and spleen for all the amazing nutrients and none of the hassle or taste you may not be used to. That's at http://NoseToTail.org We ship boxes straight to you and have free shipping options. We also have biltong if you want grass finished meat on the go. This is a traditional South African meat snack that's air dried, soft, and delicious. We have body care products made from beef tallow and only a couple other natural ingredients. We also have seasonings to go along with these wonderful products and make cooking that much easier. Make a custom box today at http://NoseToTail.org and take advantage of the free shipping options. That's how these interviews are all possible along with all the other content we produce on youtube and social media. Thanks for supporting the ranchers, my other producers, and my team. The other way you can take advantage of this win-win-win situation is at http://Sapien.org where we have the Sapien Tribe. It's a private members community where you get the extended show notes for these podcasts, discounts on NoseToTail products, zoom calls with Dr. Gary and myself, and a lot more. There's also the Sapien Program if you'd like some help making a lifestyle change. Go to http://Sapien.org to find out more. Now onto the show! GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES [5:30] Her introduction to glyphosate. [12:30] How is glyphosate still being used? [17:10] How many diseases start in the gut? [20:30] Processed foods drive micronutrient deficiencies. [22:30] Get out in the sun without sunscreen or sunglasses. [25:10] The importance of cholesterol and sulphate. [29:30] Getting a tan protects us from sunburn. [34:30] The shikimate pathway. [39:00] Animal foods limit our exposure to glyphosate. [40:30] Glyphosate is driving the celiac epidemic. [48:30] The connection between virus deaths and glyphosate. [52:30] Glyphosate impairs many enzyme processes. [56:30] How glyphosate mimics glycine in our body. [1:00:00] Epigenetic effects of glyphosate. [1:02:30] Glyphosate depletes our soil. [1:06:00] Glyphosate was made to clean metals off pipes. [1:11:40] The problem with aluminum. [1:15:30] Tips for avoiding glyphosate and heavy metals. [1:21:20] Why sulfur is so important. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

7 Juli 20211h 26min

Part 128 - Dr. Stephen Hussey MS, DC on a New Paradigm Of Heart Disease

Part 128 - Dr. Stephen Hussey MS, DC on a New Paradigm Of Heart Disease

We actually are filming a bit more for the Food Lies documentary in a few weeks at a great ranch in Oklahoma. I can't stress enough the lengths we are going to to make this the absolute best film possible. We need a mic-dropper, jaw-dropper, kale shake dropping film. ANything less won't work. It won't reach the mainstream. It won't reach Joe Cheeto out in Ohio. It won't reach the vegan in the coffee shop with the soy latte in Santa Monica. It won't reach the hilarious jokesters at the Harvard Chan School of Public Health with their comical EAT Lancet funded diet for planetary health with more added sugar and 3x the seed oils than meat. Well it probably will never reach those bought and paid for fake scientists anyway. But we are going to make it that good where someone there might watch it and realize they're living a lie and will quit their Kellogg's and Coca-cola funded position. Really interesting new paradigm on how the heart works and how atherosclerosis and other problems developed based on a bunch of research he's looked at. I don't think anyone's put it together like this before in one model like he's done. Very intriguing stuff. He attained both his Doctorate of Chiropractic and Masters in Human Nutrition and Functional Medicine from the University of Western States in Portland, OR. He is a health coach, speaker, and the author of two books on health; The Health Evolution: Why Understanding Evolution is the Key to Vibrant Health and The Heart: Our Most Medically Misunderstood Organ. Dr. Hussey guides clients from around the world back to health by using the latest research and health attaining strategies. Get his book! Get the best meat around at http://nosetotail.org Only 3 lifetime memberships left at http://sapien.org Special price on the program at http://sapien.org GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES [8:35] His background. [14:30] His past involving Type 1 Diabetes and poor metabolic health. [17:45] A brief history on the evolution of mitochondria. [21:10] The Metabolic Theory of Cancer. [23:40] The Autonomic Nervous System. [34:00] Chronic stress and the issues it can create. [39:45] Anatomy and physiology of the heart and how blood flows. [52:45] The 4th phase of water. [56:15] Free radicals. [59:30] How to mitigate excessive free radicals/oxidative stress. [1:06:00] How the heart reacts to clots and ruptures. [1:09:00] The surprising benefits of LDL and cholesterol. [1:12:10] Angiogenesis of the heart and surrounding arteries. [1:16:45] Main interventions to prevent heart disease. [1:18:30] Different ways we can get heart attacks. [1:20:20] His own experience with a heart attack and western medicine. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

30 Juni 20211h 33min

Part 127 - Dr. Pran Yoganathan on Gut Health & Chronic Disease, Human Gut Evolution, and Plant vs. Animal Food

Part 127 - Dr. Pran Yoganathan on Gut Health & Chronic Disease, Human Gut Evolution, and Plant vs. Animal Food

Hello, everyone! Thanks for sharing this podcast and giving it a review on the podcast app or itunes. I'm Brian Sanders and I'll encourage you to also work your way back and listen to all these episodes of Peak Human or start back at episode 1. I'd additionally encourage you to check out http://NoseToTail.org to check out our grass finished meats, tallow-based body care products, and more. YouTube version: https://youtu.be/jM1u5Mtnh8o Today I'm talking to Dr. Pran Yoganathan who is a Gastroenterologist and Gastrointestinal endoscopist based in Sydney. He aims to empower his patients to embark on a journey of self-healing using the philosophy of "let food be thy medicine". Dr. Pran has a special interest in conditions such as Gastro-oesophageal Reflux (GORD), Irritable Bowel Syndrome (IBS) and abdominal bloating. He takes a very thorough approach to resolve these issues using dietary manipulation In conjunction with an accredited highly qualified dietician rather than resorting to long-term medications. We talk about many of the main chronic diseases we face today on the worldwide scale and how gut health and your diet contribute to these. Anyone with a stomach and/or who eats food should find interest in this episode. Hopefully both. We talk about animal vs. plant based diets, meat and cancer, how the human gut evolved, the necessity (or lack thereof) of fiber, protein amount, meal timing, GERD and heartburn, gout, personal fat threshold, height of populations in relation to their diet, and much more. You'll like this episode if you're a fan of meat. You'll also like the aforementioned http://NoseToTail.org if you like meat and hopefully you enjoyed this silky smooth transition into some brief words about my company. This is how I have turned down all advertisers to this podcast. I'd rather steer clear of even the possibility of "strings attached" as they say. The one foundational belief I have in health and nutrition is around the ethical and sustainable production of animal foods and the inclusion of these in your diet. I work with many great producers here in the United States to produce and ship top quality food and body care products straight to you with no middle man. You can find all of our offerings at http://NoseToTail.org I'll make a deal with you so I don't bore listeners who already know about them. I'll get straight to the episode if you promise to just check out the site for 2 minutes. You will? OK thanks, just hit the pause button and we'll get straight into this episode with Dr. Pran Yoganathan. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES: [2:50] His experience and background. [7:35] The correlation between gut health and chronic disease. [11:15] Triggers for gut intestinal permeability. [13:50] Best ways of eating to have a healthy gut. [17:35] Some issues that may occur to the gut from a plant based diet. [19:50] Animal based diets to heal the gut. [24:20] Does meat cause cancer? [29:20] How the gut evolved through the years to favor more animal based food sources. [37:35] What is the optimal fuel source for our gut and body? [43:20] Is fiber necessary in high amounts? [49:10] How important is animal protein in your diet? [52:30] Timing and consistency of meals. [56:30] Resistance training to improve metabolic health. [58:20] Personal fat threshold in differences in nationalities and ethnicities. [1:04:20] The correlation of height and protein consumption in different nationalities. [1:12:00] Gerd and Gout. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

23 Juni 20211h 21min

Part 126 - Dr. Ben Bikman & Dr. Ted Naiman Discuss Competing Ideas on All Things Health (AKA Ben & Ted's Excellent Adventure)

Part 126 - Dr. Ben Bikman & Dr. Ted Naiman Discuss Competing Ideas on All Things Health (AKA Ben & Ted's Excellent Adventure)

Welcome back, friends! I'm Brian Sanders and this is the Peak Human podcast. I'm also the owner of NoseToTail.org where you can get all kinds of properly raised meats and the creator of the Food Lies film. We continue to work on the film daily and are just as desperate to finish it and get out to the world as you are. I know it's taking longer than expected, but we are making something truly special and there are a lot of factors we're dealing with. It will be worth it, trust me. This episode today is very special and a long time in the making. I got the top 2 audience favorites on one podcast. This nutrition stuff is so complex, it's never enough to get one side of the story so I thought I could at least get 2. I try to stay out of giving my opinions in this one. Perhaps 3 would be a crowd. We talk about so many interesting topics such as the carbohydrate-insulin model of obesity, the alternatives to this. The personal fat threshold, the insulin model of disease which is separate from how one becomes overweight. Satiety and how it fits into this. The processing of foods and how it plays in. Basal insulin vs. bolus. THe satiety vs. calorie theory. Also the big PUFA debate - are they as bad as they're made out to be? I think they are, but these 2 don't seem to think there's anything uniquely problematic with them other than they supply empty calories and we eat way too much of them. So they do think you should cut them out. I try to not interject much. I'm not trying to insert myself too much into these discussions. I have all kinds of guests on with differing opinions to expose people to all the angles of this complex nutrition world. I think something particularly with these guys and PUFAs, especially omega 6, is that they haven't spent the time to really dig into these details enough. They have busy lives and are focused on other areas of health. Just an idea. Really we're looking at the mystery of what goes on with food we eat and it's role in disease and/or obesity (which are independent of each other). Everyone should be interested in this to some extent. Maybe not to the level of a 90 minute podcast into some of the small details, but these are important questions that need to be answered. Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading major medical center in Seattle. His research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He has an undergraduate degree in mechanical engineering and utilizes engineering principles when dealing with complex systems such as human health and nutrition. Dr. Ben Bikman is a researcher and professor specializing in metabolic function, insulin resistance, and the drivers of metabolic disorders. He has a PhD in bioenergetics, he did a postdoctoral fellowship with the Duke National University of Singapore in metabolic disorders, and he's currently exploring the contrasting roles of insulin and ketones as key drivers of metabolic function. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES [1:00] The 4 steps of insulin resistance. [3:00] A deep dive into how insulin resistance spreads throughout the body. [8:00] Hypertrophy and Hyperplasia of fat cells. [14:00] Carbohydrate insulin model. [27:00] How refined food plays a role in obesity. [31:45] How processing, cooking, and pulverizing our food can lead to different hormonal reactions. [42:20] Differences between basal and postprandial insulin. [46:00] Obesity is a function of insulin and excessive energy intake [56:00] Are PUFAs truly as bad as they are portrayed to be? Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver [1:09:40] How refined fats and carbs affect satiation and brain chemistry. [1:18:20] A recap and discussing Brian's Uganda trip. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

15 Juni 20211h 29min

Part 125 - Stephan Van Vliet on the Cutting Edge Science Proving Meat is a Health Food

Part 125 - Stephan Van Vliet on the Cutting Edge Science Proving Meat is a Health Food

Hello everyone! Welcome back to the Peak HUman podcast, I'm Brian Sanders and I hope everyone is doing well and eating a Sapien diet and living that Sapien lifestyle. I guess I'll clarify what that is. Many people are already doing it without realizing it - I'm just trying to give it a name. It's really just what seems to be the natural human diet. It's a framework and isn't the same for everyone and changes based on many factors such as where you live to where you are in your life or health journey. It's based on whole foods, ancestral principles and food preparation techniques. It focuses on the best, most bioavailable, nutrient dense nutrition which is from animal foods. It incorporates the least toxic plant foods. It's not carnivore, keto, paleo, or Whole 30 but has elements of these. I hate to have labels but none of the other dietary labels fit what I believe is a pretty basic framework for human nutrition. The lifestyle component is big as well and includes all the natural ways humans have always stayed healhty like getting outdoors and adequate sun, sleep, a form of movement, and so on. This is such a cool episode because Dr. Van Vliet's research is a brilliant intersection of 2 topics that should be near and dear to the hearts of everyone listening - how animals are raised affects the nutrient profile of the meat and how this in turn affects human health. He uses cutting edge science to go beyond the 3 macros, or 13 vitamins & minerals listed on nutrition labels, to up to 70,000 secondary compounds found in food. He also is working on a much-anticipated study (maybe only to me and those listening) which is randomized controlled and looks at red meat in the context of a healthy diet! How cool is that! This is what we've all wanted for so long. Compare eating red meat in the context of a whole foods diet compared to eating it with a bunch of processed foods that would be thought of as a Standard American Diet. Get ready to meet your new best friend in the nutrition research field. I'm so glad Dr. Van Vliet is doing this research and that he spent a solid 90 minutes with me exploring much of it. Get ready for a good one! Dr. Stephan van Vliet is a human nutrition scientist at the Duke School of Medicine. Dr. van Vliet earned his PhD in Kinesiology and Community Health as an ESPEN Fellow from the University of Illinois at Urbana-Champaign and received post-doctoral training at the Center for Human Nutrition in the Washington University in St Louis School of Medicine. Dr. van Vliet also holds a Masters in Nutrition Science. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES: [5:15] His background and education. [8:50] Research into Metabolomics. [17:00] A deep dive into the metabolomics of faux meat and real meat. [23:50] Why the quality of your calories matter. [28:30] The importance of having a healthy dietary pattern. Cohort Profile: The 45 and Up Study Nurses Health Study: Healthful and unhealthful plant-based diets and the risk of coronary heart disease in US adults The Oxford Vegetarian Study: an overview Vegetarian Dietary Patterns and Mortality in Adventist Health Study 2 | Cardiology | JAMA Internal Medicine Lifestyle and reduced mortality among active California Mormons, 1980–2004 [40:30] His work with animal instincts and how they eat. [42:30] How the health of soil, crops and livestock are all intertwined. [51:10] Animal instincts on what they need to eat to be healthy. [58:10] Animal's special ability to eat and digest what we can not. [1:05:00] The importance of biodiversity on a rotational grazing pasture. [1:13:50] Is there such a thing as "the best diet"? [1:17:30] Combining plant and animal foods to offset some of the negatives of the other. [1:27:10] Why is it better to eat nose to tail? GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

9 Juni 20211h 31min

Part 124 - Brad Marshall on Why We Store Fat & What To Do About It

Part 124 - Brad Marshall on Why We Store Fat & What To Do About It

Welcome back, friends! I'm Brian Sanders and this is the Peak Human podcast where I talk to the world's leading health experts, doctors, researchers, and regenerative agriculture experts about how to live your best life. Please start back at episode one or at least try to work your way backwards - each episode is a valuable piece of the puzzle. Please also give this podcast a review on the Apple podcast app so we can reach more people. Today I had the pleasure of speaking with Brad Marshall who's a great guy who raises low PUFA hogs and has a lot to say about PUFAs vs. saturated fat. Brad adds to the great lineup of guests talking about the dangers of these unstable polyunsaturated fatty acids. He'll get deep into the science on why they are bad for humans and why they are what's to blame for many (or most!) health problems and chronic disease. You won't want to miss this one! Brad's work is based on his understanding of molecular biology, his love of food history and cooking and his experience in agriculture. To that end he has a genetics degree from Cornell University and a Culinary Certificate from The French Culinary Institute. After college he did cancer research at Memorial Sloan-Kettering and did bioinformatics for The Berkeley Drosophila Genome Project before leaving professional science. For the previous 15 years he has raised rotationally grazed hogs and run a retail butcher shop and USDA inspected meat processing plant. Brad has written extensively about meat processing and meat science including Disastrous Trends In American Bacon. He is also a student of culinary history and historical diets. He goes deep down a rabbit hole in the middle of the episode on the electron transport chain and goes into some pretty esoteric stuff. I hope we don't lose anyone for these 12-14 minutes. Some people may really appreciate learning how the body produces energy down to this level, but if that's not you, then feel free to skip ahead. There's a lot of valuable info we cover after this part so make sure you finish off the episode. At my company Nose to Tail we also raise low PUFA, high omega 3 ratio pigs. We do chicken as well. Check that out at http://nosetotail.org We also have the primal beef which is by far our best seller. It has liver, heart, kidney, and spleen mixed into the grass finished ground beef and tastes spectacular. I keep getting reports of how people's kids love it maybe even more than they do themselves. Our seasonings are available with your custom box. I use them every meal actually. I always put the ranch in yogurt as a sauce but I'll also use the fresh catch on smoked oysters, the primal on any and all meats, and a new thing I did was put the thai seasoning on baked sweet potatoes. That was something special. They are fresh ground and have no fillers or funny stuff. I just got my new batch of biltong and droewors in. Biltong makes beef jerky a thing of the past. It's air dried so it's softer, uses no sugars or preservatives, has extra grass fed healthy fat on it, and of course tastes amazing. We have 5 flavors to try so try them out today at http://nosetotail.org We also just added a custom cutting board with the Nose to Tail logo etched in. Use it as your plate or just chop up our fine meats on it. All of our boxes have free shipping options whether for the fresh meat or the other products. For everything else we're doing check out http://sapien.org Join the newsletter there for our weekly roundup of the best content from around the web including our own original articles and videos. That's all at http://sapien.org Now please enjoy this episode with my pal Brad Marshall. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org SHOW NOTES: [5:50] His education and background. [6:50] His mission to make high quality pork products low in polyunsaturated fat. [12:50] What he thinks is the reason for the recent obesity and chronic disease issue. [22:30] Mammals, hibernation/torpor and polyunsaturated fats. [34:40] Leptin, SCD1 and CPT1. [39:00] Reaction oxygen species, the electron transport chain and hydrogen peroxide. [49:20] How Reactive Oxygen Species (ROS) are good for your metabolism. [55:30] His own experimentation trying to get rid of his mono/polyunsaturated fatty acids. [1:01:00] His weight loss story using the Croissant Diet. [1:12:30] Satiety and leptin. [1:14:50] Insulin, saturated fat and lipolysis. [1:21:20] Fasting, weight loss and metabolic changes. [1:28:40] How metabolic rate and body temperature has plunged since 1919. [1:33:10] A recap from Brian and Brad. GET THE MEAT! http://NosetoTail.org GET THE FREE SAPIEN FOOD GUIDE! http://Sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

3 Juni 20211h 40min

Populärt inom Hälsa

somna-med-henrik
rss-bara-en-till-om-missbruk-medberoende-2
inga-beiga-morsor
alska-oss
johannes-hansen-podcast
rss-viktmedicinpodden
sova-med-dan-horning
rss-sjalsligt-avkladd
sexnoveller-deluxe
angestpodden
not-fanny-anymore
brottarbroder
rss-the-house-podcast-3
giggles-med-wiggles
sa-in-i-sjalen
till-sangs
tyngre-radio
sag-det-bara
rss-angra-inget-3
rss-en-tyngre-podd