Why Women’s Joints Are Failing 10x Faster : 1349

Why Women’s Joints Are Failing 10x Faster : 1349

Modern joint pain isn’t just wear and tear—it’s a systemic, metabolic disease that starts years before symptoms show. In this episode, you’ll learn how inflammation, mitochondria dysfunction, and immune imbalance trigger cartilage loss… and how to reverse it using targeted cytokine modulation, cellular regeneration, and smarter supplements for longevity and human performance.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Host Dave Asprey sits down with Kiran Krishnan, an expert microbiologist and advisor to Calroy Health Sciences. He’s the founder of Microbiome Labs—one of the most trusted microbiome-focused brands in functional medicine—and a formulator behind cutting-edge supplements like Arterosil and Vascanox. With over two decades of experience, Kiran has launched multiple health ventures, authored scientific textbook chapters, published clinical trials, and holds global patents in human health. He’s a leading authority on systemic inflammation, mitochondrial dysfunction, and gut-driven disease—and one of the few voices making complex biology accessible for real-world results.


He breaks down their new supplement Cartigenix HP, and how cytokines like IL-6 and TNF-alpha flip your cartilage cells from anabolic repair to catabolic destruction, how mitochondrial decline speeds up joint damage, and why most modern painkillers make your joints worse. You’ll learn how a specialized blend of boswellia and celery seed reprograms inflammation, why walking beats medication in clinical trials, and how fasting, nitric oxide, and gut health work together to optimize joint regeneration.


You’ll learn:

• How cartilage cells (chondrocytes) rely on mitochondria for tissue repair

• Why global cytokines like IL-6 and TNF-alpha drive joint degradation and brain fog

• How cartilage begins to break down in your teens—and what to do about it now

• The surprising clinical data on walking distance, inflammation markers, and recovery

• Why most supplements and NSAIDs fail—and what actually rebuilds joints

• How diet and leaky gut create 5-day inflammation spikes from a single fast-food meal

• The mitochondrial link between joint pain, cardiovascular risk, and depression

• Why perimenopausal women are at 10x higher risk for arthritis—and how to prevent it

• How to track your biological joint age using imaging and systemic inflammation labs


This is essential listening for anyone serious about biohacking, functional medicine, pain-free aging, and human performance. Whether you’re lifting heavy, walking daily, or just trying to stay mobile into old age, this episode gives you the science and tools to reverse joint degeneration and extend your healthspan.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: Joint cartilage regeneration, IL-6 inflammation suppression, TNF-alpha cytokine modulation, Chondrocyte mitochondrial repair, Catabolic to anabolic tissue shift, Osteoarthritis reversal, Rheumatoid arthritis inflammation, Mitochondria and collagen synthesis, Boswellia seratol extract, Celery seed COX inhibition, Matrix metalloproteinase (MMP) inhibition, Synovial fluid inflammation, Leaky gut and joint pain, Six-minute walk test improvement, Global cytokine markers, High sensitivity CRP reduction, ESR sedimentation rate, Uric acid crystal formation, Post-prandial glucose walking, Cartilage MRI biomarkers, Functional medicine joint support, Fasted repair stacking, Vasodilation and nitric oxide, Anti-inflammatory supplement stacking, NF-kB pathway reduction, Joint space biological age, Microvascular circulation and cartilage, Caloric load and cytokine spike, Perimenopause and arthritis risk, Joint tissue anabolic activation


**Get an exclusive discount for podcast listeners at calroy.com/dave : https://calroy.com/product/cartigenix-hp/?lp=dave **


Thank you to our sponsors!

-BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off.

-BiOptimizers | Go to http://bioptimizers.com/dave and use code DAVE15 to get 15% off your order.

-Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.

-Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order.


Resources:

• Danger Coffee: https://dangercoffee.com/discount/dave15

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 — Trailer

1:25 — Introduction

2:01 — Why Modern Medicine Fails at Joint Pain

3:07 — Painkillers That Accelerate Joint Damage

7:35 — Rheumatoid vs. Osteoarthritis Explained

8:54 — Cytokines That Destroy Cartilage

12:10 — Arthritis Begins in Your Teens

15:35 — 75% Pain Reduction in 7 Days

18:35 — The Science Behind Boswellia & Celery Seed

24:10 — Six-Minute Walk Test Results

25:45 — The $200/Month Painkiller Trap

28:53 — Proof Cartilage Can Regrow

31:01 — Mitochondria and Joint Repair

32:29 — Inflammation Links to Heart Disease

35:52 — Why Glucosamine Doesn’t Work

37:07 — Silent Arthritis in 90% of Adults

40:44 — Why Women Face Higher Joint Risk After 40

45:52 — Food as the #1 Inflammation Trigger

47:23 — Fasting & Cartogenics Stack for Repair

50:27 — Movement Snacks and Efficient Training

55:54 — Why Joints Heal Slower Than Muscles

57:48 — Dave’s Stack and Final Takeaways

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1415)

Lisa Bloomquist: Know Your Antibiotics & Restore Your Mitochondria #263

Lisa Bloomquist: Know Your Antibiotics & Restore Your Mitochondria #263

Lisa Bloomquist joins Bulletproof Radio to discuss her devastating experience with Ciprofloxacin, the important role of mitochondria and how to choose a safer antibiotic. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Nov 20151h 5min

Brendon Burchard: Hacking High Performers & Productivity Tricks #262

Brendon Burchard: Hacking High Performers & Productivity Tricks #262

Keynote of the 3rd Annual Bulletproof Biohacking Conference, Brendon Burchard sat down just after his presentation, to discuss how to be more productive every day with one easy trick, setting your intentions with a "doorframe trigger," the 5 things you need to be successful and Your Next Bold Move course on Oprah.com. Enjoy the show! Brendon Burchard is founder at the High Performance Academy, host of The Charged Life Podcast, and author of the #1 New York Times Bestsellers, The Motivation Manifesto, The Charge, and The Millionaire Messenger. Brendon has the #1 rated personal development show on YouTube, is one of the top-100 most followed public figures on Facebook, and he's shared the stage with other notable speakers such as Tony Robbins, Richard Branson, the Dalai Lama, Steve Forbes, and Katie Couric. His educational work has helped millions of people around the globe achieve the results they are looking for in the areas of business, marketing, and personal development, and his programs like the Experts Academy and World's Greatest Speaker Training have helped to jump-start thousands of people on the way to the careers they dream about. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Nov 201542min

Robert Cooper: Rewiring Your Brain & Creating New Habits #261

Robert Cooper: Rewiring Your Brain & Creating New Habits #261

Robert Cooper comes on Bulletproof Radio today to discuss the human brain, how certain words reshape your brain, developing new habits in less than a minute, and the effects of self-talk. Today's guest is a neuroscientist, New York Times bestselling author (with over 4 million books sold), and a leading high-performance business strategist. Robert Cooper serves as CEO of Cooper Neuroscience Lab and Cooper Strategic, a global consulting firm that draws on a peak performance database with more than one million leaders, professionals and teams. Robert brings a long history of working with elite performers and top leaders using neuro- science to get the most out of their brains, their time, and their performance. I sat down with Robert after his keynote address at the 3rd annual Bulletproof Biohacking Conference. He and I talked about the neuroscience of aiming your brain, how to hack the hard-wired human nature that can limit your performance, and how to build new habits that burn better programs into the structure of the brain. Find out more about Roberts work at Cooperstrategic.com. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Nov 201545min

Nir Eyal: Addictive Tech, Killing Bad Habits & Apps for Life Hacking - #260

Nir Eyal: Addictive Tech, Killing Bad Habits & Apps for Life Hacking - #260

Nir Eyal comes on Bulletproof Radio today to discuss life hacking with apps, making addictive products, being addicted to technology and FOMO (Fear Of Missing Out). Nir Eyal writes, consults, and teaches about the intersection of psychology, technology, and business. The M.I.T. Technology Review dubbed Nir, "The Prophet of Habit-Forming Technology." Nir founded two tech companies since 2003 and has taught at the Stanford Graduate School of Business and the Hasso Plattner Institute of Design at Stanford. He is the author of the bestselling book, Hooked: How to Build Habit-Forming Products, which won the "Marketing Book of the Year" award from 800 CEO Read. In addition to blogging at NirAndFar.com, Nir's writing frequently appears in TechCrunch, Inc, The Harvard Business Review, and Psychology Today. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Nov 201558min

Jackie Warner: Why You?re Sick and Tired ? #259

Jackie Warner: Why You?re Sick and Tired ? #259

Jackie Warner comes on Bulletproof Radio today to discuss her workout regiment, why protein is so important, the best sources of nutrient dense calories, and when it's a good idea to be vegetarian. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Nov 20151h 3min

Anthony Meindl: Solving Problems Creatively & Failure as an Option - #258

Anthony Meindl: Solving Problems Creatively & Failure as an Option - #258

Anthony Meindl comes on Bulletproof Radio today to discuss overcoming personal fears, what it's like coaching actors, handling problems creatively, and why failure should always be an option. Anthony Meindl is an award-winning writer/director/producer, creativity expert, inspirational speaker, and artistic director of Anthony Meindl's Actor Workshop (AMAW) with studios in Los Angeles, New York, London, Vancouver, and Sydney. AMAW was honored by Backstage four years in a row and named the Best Acting Studio in Los Angeles (Best Scene Study and Best Cold Read). Meindl is known for teaching the new generation of Hollywood stars led by Golden Globe Nominee Shailene Woodley (Divergent). He is a contributor to the Huffington Post, and Backstage. He is the author of the best-selling creativity book At Left Brain Turn Right, and his new book Alphabet Soup For Grown-Ups is available now. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Nov 20151h 2min

Dr. Amy Shah: Toxic Mold, Intermittent Fasting & Vegan vs Low Carb - #257

Dr. Amy Shah: Toxic Mold, Intermittent Fasting & Vegan vs Low Carb - #257

Dr. Amy Shah comes on Bulletproof Radio today to discuss pros and cons about western medicine, prevention through nutrition, symptoms of toxic mold exposure, vegan vs. low carb diets and intermittent fasting benefits. Dr. Amy Shah is a double board certified MD with medical training From Columbia University Medical Center, Beth Israel Deaconness/Harvard Medical School, and Albert Einstein College of Medicine. Before medical school, she graduated magna cum laude from the famed school of Nutrition at Cornell University. She has a large private practice and since 2013- online. She is releasing her first online health coaching program in October 2015 Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Nov 20151h 4min

Dr. Izabella Wentz: Hashimoto's Thyroiditis & The Root Cause - #256

Dr. Izabella Wentz: Hashimoto's Thyroiditis & The Root Cause - #256

Dr. Izabella Wentz returns to Bulletproof Radio today to discuss Hashimoto's thyroiditis, symptoms of low thyroid function, supplements you should avoid, and an interesting fact about tobacco. Izabella Wentz is a passionate, innovative and solution focused clinical pharmacist. She has had a passion for health care from a very early age. After being diagnosed with Hashimoto's Thyroiditis in 2009, Dr. Wentz was surprised at the lack of knowledge about lifestyle interventions for Hashimoto's, hypothyroidism, and autoimmune conditions. She decided to take on lifestyle interventions as a personal mission in an effort to help herself and others with Hashimoto's. After two years of researching Hashimoto's and Hypothyroidism, she decided to combine emerging knowledge with her quality improvement expertise to run rapid tests of change on herself that led her to discover the root cause of her condition. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Okt 201556min

Populärt inom Utbildning

rss-bara-en-till-om-missbruk-medberoende-2
historiepodden-se
det-skaver
nu-blir-det-historia
alska-oss
harrisons-dramatiska-historia
johannes-hansen-podcast
sektledare
allt-du-velat-veta
not-fanny-anymore
rss-sjalsligt-avkladd
i-vantan-pa-katastrofen
sa-in-i-sjalen
rss-max-tant-med-max-villman
roda-vita-rosen
dumforklarat
rikatillsammans-om-privatekonomi-rikedom-i-livet
rss-makabert
polisutbildningspodden
herrsurf