My Thyroid Health28 Okt 2025

Ep. 236: Is One Shot a Week the Future of Hypothyroidism Treatment?

In this episode, we dive into a bold new frontier in hypothyroidism care—the investigational weekly injectable version of Levothyroxine (known as XP‑8121) currently being studied by Xeris Biopharma.

For millions of people taking daily thyroid pills, the challenges are real—timing, food interactions, and absorption issues, to start. A once-weekly shot could change all of that.

In this episode, we cover:

how it works
what early trials show (higher convenience, more stable hormone levels), and
what’s still unknown (long-term safety, insurance coverage, real-world use).

If you live with hypothyroidism or care for someone who does, this episode offers a glimpse into what the future of thyroid care might look like.

🎧 Tune in and stay ahead of the curve.

LEARN MORE

You can learn more about the topic at the Paloma blog:

Once-Weekly Injectable Levothyroxine: A Future Hypothyroidism Treatment Option

https://www.palomahealth.com/learn/once-weekly-injectable-levothyroxine-future-hypothyroidism-treatment

ABOUT PALOMA HEALTH

⁠⁠Paloma Health ⁠⁠⁠⁠⁠⁠⁠⁠is an online medical practice focused on treating hypothyroidism, Hashimoto’s, perimenopause, menopause, and hormonal weight gain. From online visits with your provider to easy prescription management and lab orders, we create personalized treatment plans for you.

Become a member⁠, or try our at-home test kit and experience a whole new level of hypothyroid care. Use code PODCAST to save $30 at checkout.

Disclaimer: The $30 discount is only valid for first-time Paloma Health members and test kit users. Coupon must be entered at the time of checkout.

Become a Paloma Member

https://www.palomahealth.com/pricing-hypothyroidism

Paloma Complete Thyroid Blood Test Kit

https://www.palomahealth.com/home-thyroid-blood-test-kit

➡️ Follow Paloma Health for the latest hormonal health news and expert-backed insights on thyroid and hormonal health, medication management, and lifestyle tips that will help you feel your best!

Upptäck Premium

Prova 14 dagar kostnadsfritt

Skaffa Premium

Avsnitt(287)

PCOS and Hashimoto's Disease feat. Dr. Stacy Henigsman and Felice Ramallo, RDN

Dr. Stacy Henigsman and Dietitian Felice Ramallo from Allara Health discuss the connection between Hashimoto's disease and polycystic ovary syndrome (PCOS) and how to manage both conditions. In this...

9 Feb 202257min

Identifying Pharmacy Issues and Support for Thyroid Patients feat. Dr. Jessica Nouhavandi and Dr. Donna Mazzola

Honeybee Health Co-Founder Dr. Jessica Nouhavandi and Pharmacist Dr. Donna Mazzola talk about how to best navigate the pharmacy experience as a thyroid patient. In this episode— What is a narrow th...

2 Dec 202157min