How to Build Muscle WITHOUT Lifting! Biohacker Longevity   : 1362

How to Build Muscle WITHOUT Lifting! Biohacker Longevity : 1362

Your workouts may be doing less than you think, and science now proves why. This episode reveals how to build muscle, improve metabolism, and extend longevity in a fraction of the time using blood flow restriction training and intermittent hypoxia. You’ll learn how to hack your mitochondria for faster recovery, stronger hormonal balance, and better brain performance without the burnout of high-intensity training.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Host Dave Asprey talks with Dr. Sten Stray-Gundersen, PhD, CSCS, one of the world’s leading experts on blood flow restriction (BFR) training and metabolic physiology. With over a decade of research and teaching experience, Dr. Stray-Gundersen has explored how BFR and intermittent hypoxia can improve cardiovascular health, metabolism, and recovery. After earning his doctorate in Exercise Physiology from the University of Texas at Austin, he now serves as an Assistant Professor at the University of South Carolina, where he studies vascular adaptations, cognitive performance, and ergogenic aids. He’s also a B Strong master trainer, developing individualized BFR protocols for athletes, military professionals, and everyday people looking to optimize human performance.


Together, Dave and Sten uncover how BFR and oxygen cycling unlock powerful adaptations in the body’s vascular, metabolic, and hormonal systems. You’ll learn how strategic stress signals can trigger nitric oxide production, enhance glucose uptake, improve insulin sensitivity, and supercharge mitochondria for better energy and anti-aging benefits. They also explore how these methods can naturally boost testosterone, growth hormone, and even libido, all while protecting the nervous system and improving recovery.


This episode dives deep into biohacking, functional medicine, and smart exercise efficiency, from Zone 2 and REHIT training to nitric oxide signaling, fasting, nootropics, and precision supplementation. Whether your goal is longevity, strength, or sharper cognition, this conversation shows you how to get maximum results with minimal time using the principles of Smarter Not Harder.


You’ll Learn:

• How intermittent hypoxia works at the level of partial pressure and why altitude acclimation upgrades mitochondria and performance

• Why hypoxia and muscle contraction increase glucose uptake independent of insulin and improve insulin sensitivity

• How blood flow restriction (BFR) accelerates fatigue with light loads to drive hypertrophy, strength, and vascular adaptations

• How BFR and hypoxia influence testosterone, growth hormone, nitric oxide, and libido through short, targeted stress

• The roles of ENOS, INOS, and NNOS in nitric oxide signaling and what that means for circulation and brain perfusion

• Who benefits most from BFR, including athletes, rehab patients, and older adults who cannot lift heavy

• Why BFR produces systemic and “proximal” gains, including carryover to glutes and upper body during lower limb training

• How to stack BFR with Zone 2, REHIT, and vibration plates for VO2 max, muscle, and time efficiency


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: Sten Stray-Gundersen, blood flow restriction training, B Strong, intermittent hypoxia, mitochondrial function, nitric oxide production, VO2 max, metabolic efficiency, vascular health, testosterone boost, growth hormone release, anti-aging performance, exercise recovery, glucose metabolism, functional medicine, biohacking fitness, REHIT training, Zone 2 optimization, strength and longevity, human performance science


Thank you to our sponsors!

-KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off.

-EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.

-Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE.

-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.


Resources:

• Use code DAVE10 to get a discount on a BFR band today: https://shopify.bstrong.training/products/b-strong-training-system?ref=dave%2F

• Dive deeper in Sten’s work at: https://bstrong.training/

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 - Trailer

1:25 - Guest Intro

5:40 - Intermittent Hypoxia & Altitude Acclimation

12:11 - Introduction to Blood Flow Restriction (BFR)

22:53 - Systemic Benefits & Who Can Use BFR

30:23 - BFR Effects on Hormones & Libido

40:37 - Nitric Oxide & Vascular Health

48:15 - Zone 2 Training with BFR

54:00 - Advanced Protocols: Stacking BFR

59:15 - Cognitive Enhancement & Wrap-Up

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1421)

Male Hormones: How Testosterone and Toxins Mess With You! – Tracy Gapin, M.D.

Male Hormones: How Testosterone and Toxins Mess With You! – Tracy Gapin, M.D.

In this special Asprey Archive episode you’ll learn that while yes, testosterone fuels energy and performance, it’s not the be-all and end-all solution for men’s health woes. A systems biology approach considers many other aspects and provides a broader perspective about what’s going on with you.This conversation features board-certified urologist Tracy Gapin, M.D. He joined us in 2022 for this episode to discuss new ways for men to improve their health and performance. He uses epigenetic coaching, hormones, peptide therapy, biometric monitoring, and unique nutrition and lifestyle interventions.In his book, “Male 2.0™: Cracking the Code to Limitless Health and Vitality,” he says medical school, residency training and even a two-decade career in urology and surgery specialties didn’t teach him how to get to root causes of men’s issues and solve them. He had a health crash of his own at 42. Since neither he nor his doctor had good answers, he went on a quest of discovery and change. He founded the Gapin Institute for High Performance Medicine and created the proprietary N1 Performance Health Program to go beyond conventional options.This conversation goes even further into what creates epigenetic signals that affect the function and expression of your genes. You’ll learn, too, that your mindset, stress and environment—and how you do or don’t control those things—have everything to do with your energy and focus. If you’re aiming for higher performance, Dr. Tracy suggests a trifecta that makes sleep a priority, builds resilience to stress, and creates consistent behaviors with intention.Sponsors:EnVy | Go to https://www.envypillow.com/ and use code DAVE10 at checkout for an exclusive discount.Resources:Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: Gapin Institute for High Performance MedicineInstagram: @DrTracyGapinInstagram: @Dave.AspreyYouTube: @DaveAspreyBPRSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Apr 202451min

The Science Behind Memory - Dr. Charan Ranganath : 1152

The Science Behind Memory - Dr. Charan Ranganath : 1152

In today’s episode you’ll explore the complexities of memory with Dr. Charan Ranganath, a top expert in cognitive neuroscience. This episode takes you through the fascinating ways our brains record, process, and utilize memories to navigate daily life and shape our futures. You’ll learn how memory impacts decision-making, the truth about common myths, and the role of groundbreaking research in our understanding of cognitive function. Dr. Ranganath shares insights from his book "Why We Remember," shedding light on the brain's ability to predict and prepare for what comes next. Whether you're a seasoned biohacker or just starting, this conversation offers valuable perspectives on the science of memory that will change how you think about your mind.Timestamp highlights (00:01:03) The Role of Memory in Shaping Our Reality (00:04:51) The Truth about Remembering and Forgetting (00:12:27) Psychedelics, Plasticity, and the Future of Memory Research (00:16:32) The Ethics of Memory Enhancement (00:21:10) Harnessing Memory for Predicting the Future (00:29:17) How Memory Evolves with Age (00:33:27) The Power of Pattern Recognition in Human Intelligence (00:38:34) Debunking Memory Myths with Dr. Ranganath (00:40:54) The Role of Diet and Lifestyle in Memory Preservation (00:50:18) What 'Spider Sense' Says About Our Predictive Brains (00:55:10) Building a Life of Meaningful Memories (00:59:42) How Long Would You Want to Live if Your Memory Stayed Intact? Sponsors Sunlighten | Head to Sunlighten.com/dave to save up to $600 STEMREGEN | Go to STEMREGEN.co/Dave for 20% off Resources Get your copy of 'Why We Remember' by Dr. Charan Ranganath Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Follow Dr. Ranganath on Instagram: @TheMemoryDoc See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Apr 20241h 21min

Hack Your Hunger: The Power of GLP-1 Probiotics - Colleen Cutcliffe, Ph.D.  : 1151

Hack Your Hunger: The Power of GLP-1 Probiotics - Colleen Cutcliffe, Ph.D. : 1151

Join Dave Asprey for a fascinating discussion with Colleen Cutcliffe, Ph.D., on leveraging the power of GLP-1 for natural weight management and overall well-being. Discover how probiotics can naturally stimulate GLP-1 production in the body, helping reduce food cravings and maintain a healthy gut lining. We delve into the differences between pharmaceuticals and natural probiotics, the importance of GLP-1 for longevity, and practical tips for optimizing your microbiome health. Whether you're battling cravings or seeking to prevent diabetes and its associated risks, this episode sheds light on natural, effective strategies for a healthier life. Timestamp Highlights: (00:00:01) Introduction to GLP-1 and weight management (00:01:06) Colleen Cutcliffe, PhD, on natural ways to stimulate GLP-1 (00:04:41) The role of microbiome in regulating GLP-1 and cravings (00:16:00) The GLP-1 probiotic: benefits beyond weight loss (00:34:13) Dietary interventions to support GLP-1 probiotics (00:42:23) Personal experiences and results with GLP-1 probiotics (00:51:01) The different pendulum products and who should take them (00:59:23) How GLP-1 probiotics impact the gut lining and overall health (01:03:56) GLP-1 and its connection to longevity and disease prevention Sponsors: Pendulum | Get 20% off membership at https://pendulumlife.com with code Asprey20 ARMRA | Go to https://www.TryARMRA.com and use code Dave for 15% off ARRC LED | For More Information Visit ARRCLED.com Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Instagram: @Dave.Asprey Pendulum GLP-1 Probiotics: https://pendulumlife.com (Code: Asprey20 for 20% off) Instagram: @pendulumlifecoSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Apr 20241h 5min

Prioritize Performance, Not Fame - Ramon Hervey II : 1150

Prioritize Performance, Not Fame - Ramon Hervey II : 1150

Today you'll step inside the real world of fame with Ramon Hervey II, the mastermind manager behind iconic figures like Vanessa Williams, Bette Midler, and Richard Pryor. He is author of "The Fame Game: An Insider's Playbook for Earning Your 15 Minutes." With years of experience guiding celebrity journeys, Ramon dismantles the myths surrounding fame and success. In this episode, he shares invaluable insights on why pouring your heart into your work and letting excellence lead is more fulfilling and enduring than the pursuit of fame. Ramon, a Master of Media and public perception, brings a wealth of knowledge from his time shaping the narratives of household names. Get ready to redefine your ambitions and align your pursuits with the values that truly matter. You’ll step beyond the veneer of fame into a world where your achievements stand the test of time. (00:00:06) Introduction to the complexities of fame (00:01:06) Ramon's correction and insights into the unpredictability of fame (00:04:04) The statistical rarity of becoming famous (00:06:03) The truth behind fabricating fame in the entertainment industry (00:09:18) The importance of authenticity and integrity (00:21:54) Ramon's experience with the toxic side of fame (00:29:32) The gratitude for positive fan interactions (00:32:13) Ramon's advice for influencers on handling fame (00:41:19) How industries can shift and impact your fame (00:42:27) Dave's creation of the biohacking movement (00:48:41) The strategic management of public image and fame (00:52:10) The dangers of seeking fame for fame's sake (00:58:55) The misuse of fame and its consequences (01:07:13) The role of media and public perception (01:14:04) Ramon's take on fame as currency and liability (01:20:22) The Tenets of Fame - managing fame without destruction Sponsors: Timeline Nutrition | Go to https://www.timeline.com/dave and get 10% off your first order 40 Years of Zen | Go to https://www.40YearsOfZen.com/Dave for an exclusive offer.Resources: Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: www.herveyandcompany.com IG - @trichemon FB - Ramon Hervey II Twitter: @coolramon See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Apr 20241h 19min

Female Hormones: What Disrupts, Detoxes & Balances Them! – Anna Cabeca, D.O.

Female Hormones: What Disrupts, Detoxes & Balances Them! – Anna Cabeca, D.O.

Today you’ll learn about female hormones: what they are, what they do, and what disrupts them. You’ll learn about the hormonal shifts that happen at different ages and life stages and get tips on how to balance hormones and make them work for you, not against you.This conversation features Anna Cabeca, D.O.. Dr. Anna is a Doctor of Osteopathy who’s triple-board certified in gynecology and obstetrics, integrative medicine, and anti-aging and regenerative medicine. She has additional certifications in functional medicine, sexual health, and bioidentical hormone replacement therapy. She joins this special preview episode to talk about female hormones. It’s her particular area of expertise and one of The Human Upgrade’s all-time Top 10 podcast topics. Today’s hormone discussion includes:How hormone disruptors go beyond stress to mold, and product and environmental toxinsHow estrogen levels change over timeWhat’s going on with progesterone, pregnenolone and DHEA, tooWhat happens to hormones during perimenopause and menopauseWhat’s causing brain fogWhat to know about bioidentical hormonesHow detoxing affects hormonesHow to keep your vaginal microbiome balancedHow “food as medicine” helps balance hormonesHow hormones influence longevityAnd much more!For the past 20 years, Dr. Anna's educated and helped women with their hormones through her private practice, books, online videos and articles. Learn more about her work with women’s hormone health:“MenuPause: Five Unique Eating Plans to Break Through Your Weight Loss Plateau and Improve Mood, Sleep, and Hot Flashes”“The Hormone Fix: Burn Fat Naturally, Boost Energy, and Stop Hot Flashes the Keto-Green™️ Way”“Keto-Green™️ 16”Sponsors:Quantum Upgrade | Go to https://quantumupgrade.io/dave for a 7-day Free TrailNeurohacker Senolytic | https://Neurohacker.com/Dave to get 15% off.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Apr 202456min

The Dawn of a New Era in Cancer Screening - Dr. Josh Ofman : 1149

The Dawn of a New Era in Cancer Screening - Dr. Josh Ofman : 1149

What if you could catch cancer in its earliest stages, when it's most treatable—would you seize that chance? Our guest today is Dr. Josh Ofman, the president of GRAIL, and he's pioneering early cancer detection in a revolutionary new way. You'll discover the cutting-edge advances in multi-cancer early detection that are transforming the fight against this swift and silent killer. You'll also learn about the full potential of the GRAIL gallery test in your proactive health management. This technology is ushering in a new era in cancer care but also signals a paradigm shift in disease prevention. Learn why yearly screenings are your best strategy in the race against cancer. Prepare to dive deep into how the latest biotech innovations could significantly extend your life span!Timestamp Highlights (00:01:03) An Unsettling Trend in Cancer Proliferation (00:04:51) Introducing Dr. Josh Ofman and the GRAIL Test (00:12:27) The Revolutionary Approach of Multi-Cancer Early Detection (00:16:32) The Shift to Biological Signals in Cancer Detection (00:21:10) The Empowering Aspect of Knowing Your Cancer Status (00:29:17) How GRAIL's Gallery Test Can Change the Paradigm of Cancer Treatment (00:33:27) The Critical Nature of Annual Cancer Screening (00:38:34) How Early Detection Affects Treatment Options and Survival (00:40:54) The Future of GRAIL in Other Disease Pathways (00:50:18) Combating Fear and Misconceptions Around Cancer (00:55:10) The Impact of Socioeconomic Factors on Cancer Incidence (00:59:42) The Pivotal Role of Data in Personalized Health Sponsors ARRC LED | The perfect device for daily home use. For more information visit arrcled.com. Leela Quantum | Visit www.LeelaQ.com/Dave for 10% Off Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’: daveasprey.com/books GRAIL Multi-Cancer Early Detection Test: Visit www.Galleri.com/Dave to see if you’re eligible for a $50 off limited-time online-only offer. GRAIL Research and Studies: grail.com/clinical-studies GRAIL on Twitter: @GRAILbio See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Apr 202447min

Molding the Future of Wellness: Synthesizing Spirit and Science – Dr. Christina Rahm  : 1148

Molding the Future of Wellness: Synthesizing Spirit and Science – Dr. Christina Rahm : 1148

I had the pleasure of talking with Dr. Christina Rahm, who has an inspiring journey from a pharmaceutical executive to an advocate for integrating holistic health solutions with rigorous scientific methods. We dive into the impact of spirituality on wellness, the transformative power of neural feedback, and the intersection of technology and ethics in health. Dr. Rahm shares her insights into combating health issues with nanotechnology and discusses the influence of the environment on our well-being.(00:00:01) Introducing Dr. Christina Rahm and her diverse expertise in health and science (00:02:17) The transparency and ethics in the pharmaceutical industry (00:07:07) Transition to holistic health solutions and bioengineering innovations (00:14:10) Addressing the pervasive health effects of fungus and mold (00:27:11) Biotechnology's role in creating a brighter future for human health (00:38:04) Discussing the unexpected benefits of childhood diseases on immune function (00:50:31) Exploring annual detox rituals and their scientific basis (01:03:01) Handling criticism with humor: The "Your Mom" strategy(01:06:57) Announcement of Upgrade Labs locations and offerings Sponsors: Mitosynergy | Exclusive offer for listeners – 15% off by going to www.Mitosynergy.com/Dave ARMRA | Go to www.TryARMRA.com and use code Dave to get 15% off your First Order Resources: Dr. Christina Rahm's website: https://drchristinarahm.com/ Root Brands: https://therootbrands.com/ Upgrade Labs: https://upgradelabs.com/ Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Dr. Chrsitina Rahm’s Instagram Page: https://www.instagram.com/drchristinarahm/ See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Mars 20241h 16min

The Power of Perseverance - Maria Menounos : 1147

The Power of Perseverance - Maria Menounos : 1147

In this profound episode, Maria Menounos shares her journey through significant health challenges, including a brain tumor and diabetes, and how she emerged more resilient and health focused. Renowned for her vibrant career in entertainment and now as a wellness advocate, Maria delves into the transformative power of facing mortality, redefining medicine, and leveraging biohacking to enhance her life. She gives actionable advice for those looking to preserve their health while pursuing their dreams and the importance of aligning career success with personal well-being. (00:00:01) - Maria's resilience through her health battles (00:03:29) - How health challenges can redefine life's purpose (00:14:18) - Yoga Nidra and the shift from anxiety to empowerment (00:23:25) - The importance of biohacking in Maria's recovery (00:34:16) - Sunlight and its underrated health benefits (00:47:30) - The rise of biohacking technologies and their accessibility Sponsors BiOptimizers | Go to www.bioptimizers.com/Dave for 10% off Timeline | Go to www.TimelineNutrition.com/Dave to get 10% off your first order Resources Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Heal Squad: https://www.healsquad.com/ Maria Menounos Instagram: @mariamenounos See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Mars 20241h 12min

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