BBC Inside Science

In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. Costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief.Of all the ways the UK can now diverge from the EU, DEFRA is currently holding an open consultation on whether to tweak the current GMO regulations so as not to include CRISPR-style Genetic Editing. The EU is coincidentally looking at the same issue. John Innes Centre's Janneke Balk works on making strains of wheat that have a higher level of iron for nutritional fortification. Interim head of the Roslin Institute in Scotland Bruce Whitelaw thinks developing disease resistance in farm animals is a potentially profitable area. Both agree the GMO regulations should be more tightly specified to bring clarity and opportunity for innovation. In Iceland, Kari Stefansson's company Decode Genetics analyze the genetic codes of most of the population of Iceland. This has allowed them to look at the parents, siblings, and offspring of identical twins, and identify how early genetic differences between them develop. And it's very early indeed. Given that identical twins studies are so often used to address issues surrounding the so-called Nature-vs-Nurture debate, the findings, published in the Journal Nature, are striking. Presenter by Marnie Chesterton Produced by Alex MansfieldMade in association with the Open University.

14 Jan 202132min

After the decision by the UK government last week to change the spacing between dosings of vaccine from the recommended 3 weeks to 12 weeks, immunologists around the world have been discussing with some urgency the wisdom of such a move. The FDA and the WHO are deeply sceptical, and the manufacturers have distanced themselves to some extent, by cautioning not to deviate from the regime tested in last year's phase III trials. The thinking behind the move is to get more people injected with a single dose in a shorter time, and that the longer wait for the second shot is worth the risk, if it means more people receive some level of protection in the short term.Clinical Epidemiologist Dr Deepthi Gurdasani and Immunoligist Prof Danny Altmann of Imperial College describe to Marnie how evidence, experience and hunch are combining in the face of the covid crisis, and quite what we know, what we don't and what we could, about this nationwide experiment. Increasingly, ecologists wanting to monitor remote areas are relying on such things as solar powered audio recorders to measure biodiversity in the sounds of the wild. But how to scrutinize years and years worth of 24 hour, multi-site recordings? Sarab Sethi and colleagues have not only been leaving solar-powered Raspberry Pi recorders out in the jungles of Borneo, they've been using machine learning techniques to look out for species and biodiversity changes from afar. You can listen to some of the Borneo work at the SAFE acoustic website (link on BBC page below).Presented by Marnie ChestertonProduced by Alex MansfieldMade in collaboration with the Open University.

7 Jan 202138min

As a new decade ticks over, Dr Adam Rutherford, Professor Alice Roberts and Professor Brian Cox look back on a decade of science that has transformed perceptions of our medicine, our history and our universe.From advances in genetics that have brought personalized medicine to reality, and revealed the ghosts of ancestral human species never before identified, to quantum computing lessons that hint at the nature of existence and causation throughout the universe, it has been an interesting time. New observational technologies have revealed fresh windows in time and space. And all of it has been reported by BBC Inside Science. But what of the next decade? Programme may contain traces of informed speculation, but (almost) no references to Covid.Presented by Adam Rutherford Produced by Melanie BrownMade in association with The Open University.

31 Dec 202038min

Nobody could have failed to notice the one story dominating the science news this year - but what about the discoveries that have been overshadowed in 2020? This week, Dr Adam Rutherford eschews all mentions of the pandemic as he invites dinosaur researcher Dr Susie Maidment, climate scientist Dr Tamsin Edwards and astrophysicist Dr Emma Chapman to share their science highlights of the year. We journey to the moon and beyond to discuss the many missions that have been blasting and grabbing bits of space rock to bring back to earth and tackle the ongoing debate about whether signs of life have been found on Venus. Back down on earth, this year could be one of, if not the, hottest years on record, with particularly high temperatures in the Arctic Circle. What might a warming world mean for ice-shelf collapse in Antarctica and how are governments responding? We discuss Joe Biden’s presidency, UK carbon emissions and what China’s recent announcements of net zero by 2060 might mean for the future of the planet. And despite limitations on travel this past year, exciting discoveries in the dinosaur world have nonetheless continued with what is believed to be the first aquatic dinosaur. The detection of soft shell eggs is also changing understandings of how dinosaurs reared their offspring.And if that wasn’t enough, Dr Adam Rutherford challenges our experts to predict what big science stories might lie on the horizon in 2021.

24 Dec 202032min

Dr Alex Lathbridge with your peek at the week in science.This week in the House of Commons Matt Hancock announced a new variant in the Covid virus, discovered to be spreading through the south east of the UK. As Professor Jonathan Ball of the University of Nottingham describes, there have been many slight mutations and changes to the DNA in the virus since it first emerged, and most are of no added danger. But it is important that new ones - and new combinations of them - are tracked through collaborations and networks such as COG-UK, who provide an almost real-time track of the spread of new mutations. The new one this week is of some interest as it involves a slight change to the protein of the binding area on the virus, but much lab work remains to be done,Is an angry face always an angry face? A paper in the Journal Nature this week uses Machine Learning to scan millions of videos of faces on YouTube to shed light on an old problem - the universality of facial expressions in people. The authors - working with Google - suggest that broadly speaking, in a number of contexts such as weddings and sporting events, people in much of the world tend to pull the same faces. But as Lisa Feldman Barrett - who wrote an accompanying commentary in the same journal - suggests, the way Machine Learning approaches in this area require very human perceptions to train the algorithm in the first place, means care must be taken before inferring too much.This year BBC Inside Science has been showcasing some of the mystery objects the Science Museum has uncovered in the course of moving its collections to a new home in Wroughton, Wiltshire. Jessica Bradford talks to Alex about our next one. If you have any ideas what it might be for, you can let them know by dropping a note or memory to mysteryobject@sciencemuseum.ac.uk Presented by Alex Lathbridge Produced by Alex MansfieldMade in Association with The Open University

17 Dec 202033min

Dr Alex Lathbridge brings you the week in science.As the first COVID vaccines are delivered this week hastening the first glimmers of a return to normal life, is it too soon to be thinking about other future threats to humanity? James Arbuthnot, chair of a House of Lords select committee tasked to look at risk planning, and fellow committee member Martin Rees discuss their meeting this week and the assessment of the scientists invited to share their interpretations of future threats like AI, solar flares and volcanic eruptions. They are inviting evidence submissions until January 28th 2021.The Millennium Seed Bank was setup as a safety net to protect and conserve rare, threatened and useful wild plants for generations to come. As it celebrates 20 years of operation it can claim to host 16 per cent of the world’s bankable flora in its sturdy underground vaults. Alex heads down to the Royal Botanic Gardens in Wakehurst, Sussex, and meets the team coaxing seeds to life to check their viability or using cryopreserving on those seeds less convivial to being preserved. One key project is protecting farmed crops that have lost genetic diversity over time and are at risk from climate change. Through collecting and researching the wild ‘cousins’ of our modern day crops Wakehurst, Kew Gardens and its partners are researching and harnessing the resilient traits found in these less pampered crop relatives. Treezilla.org is a citizen science project designed to increase understanding of all the urban tress in the UK. Scientists, together with the public, are getting their tape measures out and cataloguing the trees to better ascertain how they influence the environment in towns and cities across the UK, to map their ages, species, sizes and health, and to help future planners to put the knowledge to work. Kate Hand is a researcher at the Open University who is looking at ways to increase our knowledge of the values trees bring to our urban environments – specifically through the lens of Milton Keynes which, it transpires, is quite the urban arboretum.

10 Dec 202036min

Has one of the biggest problems in biology been solved by AI? Dr Alex Lathbridge brings you the week in science.This week google's Deep Mind team presented results of their latest efforts at cracking the 50 year old problem of Protein Folding. AlphaFold has built on previous success at predicting the 3D structures of biological proteins from just knowing the sequence of amino acids of which it is made. It is a computational problem that thousands of researchers around the world have been trying to solve for decades. There are millions of different proteins doing all the work in living cells, but simply knowing what their constituent chemicals are is not enough to understand how they are shaped, and therefore how they work. Scientists are optimistic that solving the problem will herald a new era in medicine, agriculture and even sustainable recycling. Prof John Moult, founding chair of CASP - the international body that monitors progress in the field, tells of the remarkable breakthrough being discussed this week.Whilst China is trying to bring back samples of the moon this week, a much longer-lived space mission to an asteroid hopes this weekend to return samples of the earliest bits of the solar system to earth. Hyabusa 2 will complete a 6 year mission, Japanese scientists hope, this weekend when a small package of asteroid sample drops into the atmosphere above Australia on Sunday morning.And as students across the UK prepare to make their ways home for the holidays, GP Margaret McCartney and Kavita Vedhara of Nottingham University discuss some of the challenges of fast mass covid testing and false negatives.Presented by Alex Lathbridge Produced by Alex Mansfield and Melanie Brown.

3 Dec 202036min

Last weekend a joint European-US satellite blasted into space to begin its mission - monitoring the oceans back here on earth. Sentinel 6 Michael Freilich is one of a long line of satellites and has a striking design – appearing like a bright gold farmyard barn with a big pitched roof. Anand Jagatia speaks to Dr Ralph Cordey at Airbus Space and Defence about the latest design iteration and the technology on-board. Oceanographer Professor Penny Holiday from the National Oceanography Centre explains how Sentinel 6’s readings will enhance understanding of sea-level rises and give more detail about the currents in our oceans.We journey back to the cosmic ‘Dark Ages’, a period of time that we know hardly anything about. Dr Emma Chapman is an astrophysicist at Imperial College London who has written a book ‘First Light: Switching on Stars at the Dawn of Time’ to throw light on this illusive chapter in the history of our universe. How close are scientists to finding the first stars?With ambitious new government targets to end the sale of petrol and diesel cars by 2030 how ready are electric cars to fill the gap? One key area many companies are trying to improve are the batteries powering electric vehicles. Peter Bruce, professor of materials science from Oxford University and chief scientist at the Faraday Institution has been working on rechargeable lithium ion energy storage since the 1990s. He speaks with Anand about the current limitations and the most recent developments in battery research and development.Presented by Anand Jagatia Produced by Melanie Brown

26 Nov 202030min