
Tenlee’s Story: Thriving After a Heart Transplant
Tenlee was born with a rare heart condition and had a heart transplant at Children’s Hospital of Philadelphia when she was just 5 months old. And though she’s doing well today, her journey has been ve...
31 Mars 202318min

Kareem’s Story: Advocating for Trauma-Informed Care
While growing up in West Philadelphia, Kareem saw firsthand the devastating impact trauma and violence can have on children. In this episode of The Breakthrough Chronicles, he and Madeline discuss the...
31 Mars 202314min

Hannah’s Story: Moving Beyond Blindness
When Hannah was a baby, she was diagnosed with a rare eye disease that usually leaves patients completely blind. But Hannah’s story turned out differently thanks to an incredible gene therapy develope...
31 Mars 202312min

Emily’s Story: Celebrating 10 Years Cancer Free
Emily was just 6 years old when she received CAR T cell immunotherapy for relapsed leukemia at Children’s Hospital of Philadelphia. Emily was the very first child to receive this groundbreaking treatm...
31 Mars 202313min

Special Bonus Episode: Addy and Lily’s Separation Story
When Addy and Lily Altobelli were born in CHOP’s Garbose Family Special Delivery Unit, they needed highly specialized care because they were conjoined – their bodies were connected at the chest wall, ...
24 Maj 202220min

“Do What You Love”: Finding Medicines for Rare Diseases
Hematologist and oncologist Denise Adams, MD, specializes in treating vascular anomalies, which occur when arteries, capillaries, veins or lymphatic vessels fail to develop correctly. She joins Madeli...
23 Mars 202211min

“I’ve Always Loved to Ask Why”: The Power of Mitochondrial Medicine
Our mitochondria make the energy that keeps us alive. Geneticist Marni Falk, MD, joins Madeline to discuss what happens when our mitochondria don’t work properly, the breakthroughs she and her team ar...
23 Mars 202218min

“There Was an Unmet Need”: Breakthroughs in Endocrinology
While growing up in Panama, Diva DeLeón-Crutchlow, MD, MSCE, always wanted to understand how things worked. She speaks to Madeline about how her curiosity led her to pursue a career in medicine – and ...
23 Mars 202225min





















