
Achieving results in the physical world, with Adam Jarvis of “Public Service”
Patrick McKenzie is joined by Adam Jarvis, author of the Public Service substack and a New Zealand civil engineer and public sector veteran. They discuss how political capital constraints, funding mis...
3 Juli 20251h 9min

The AI infrastructure stack with Jennifer Li, a16z
In this episode, Patrick McKenzie (@patio11) is joined by Jennifer Li, a general partner at a16z investing in enterprise, infrastructure and AI. Jennifer breaks down how AI workloads are creating new ...
26 Juni 202545min

Getting better at LLMs, with Zvi Mowshowitz
In this episode, Patrick McKenzie (patio11) recorded with Zvi Mowshowitz (TheZvi) live at the LessOnline conference. They explore practical strategies for getting better results from large language mo...
12 Juni 202551min

Machine learning meets malware, with Caleb Fenton
Patrick McKenzie (patio11) discusses software reversing and AI's transformative impact on cybersecurity with Caleb Fenton, co-founder of Delphos Labs. They explore how LLMs are revolutionizing the tra...
5 Juni 20251h 21min

How to negotiate your salary package
In this episode, Patrick McKenzie (patio11) revisits his widely-shared negotiation essay, which he notes may be the most impactful thing he's done in his career aside from VaccinateCA. The essay cover...
29 Maj 202545min

The capitalist's guide to podcasting, with Ross Rheingans-Yoo
In this episode, Patrick McKenzie (patio11) and returning guest Ross Rheingans-Yoo discuss the strategic advantages of starting a podcast, particularly for professionals seeking to build trust, expand...
22 Maj 20251h 3min

Killing viruses with light, with Jacob Swett
In this episode, Patrick McKenzie (patio11) is joined by Jacob Swett of Blueprint Biosecurity to discuss far UVC technology - a specialized wavelength of UV light that kills airborne pathogens while r...
15 Maj 20251h 1min

Life insurance and your money, with Zac Townsend
In this episode, Patrick McKenzie (patio11) is joined by Zac Townsend, a serial founder and CEO of Meanwhile, a fully regulated life insurance company operating in Bitcoin. They explore the difference...
8 Maj 20251h 20min



















