From First Principles

From First Principles

From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.

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Avsnitt(52)

New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics) (EP 44)

New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics) (EP 44)

Hosted by Lester Nare and Krishna Choudhary, this episode marks Krishna’s return to the studio after paternity leave — and the timing could not be more fitting. Today’s deep dive is about inheritance:...

26 Juni 1h 37min

Dr. Michael Blanton on Open Data, Galaxy Surveys, and the Future of Astronomy (EP 43)

Dr. Michael Blanton on Open Data, Galaxy Surveys, and the Future of Astronomy (EP 43)

Hosted by Lester Nare and Krishna Choudhary, this episode is the second interview in our ongoing collaboration series with Carnegie Observatories. Krishna sits down with Dr. Michael Blanton, the new D...

4 Juni 43min

How Scientists Actually Study Dark Matter (EP 42)

How Scientists Actually Study Dark Matter (EP 42)

Hosted by Lester Nare, this episode features astrophysicist Dan Gilman for a deep conversation on one of the biggest open questions in modern physics: what dark matter actually is. Starting from first...

21 Maj 1h 6min

Dr. John Mulchaey on Carnegie Science and the Future of Astronomy (EP 41)

Dr. John Mulchaey on Carnegie Science and the Future of Astronomy (EP 41)

Hosted by Lester Nare and Krishna Choudhary, this interview features John Mulchaey, the 12th President of Carnegie Science and former Director of the Carnegie Observatories. The conversation starts wi...

13 Maj 37min

Ant Scans, Lunar Chickpeas, Hidden Galaxies & Superconductivity (EP 40)

Ant Scans, Lunar Chickpeas, Hidden Galaxies & Superconductivity (EP 40)

Hosted by Lester Nare and Krishna Choudhary, this rundown episode covers four new science stories at a high level: a huge new 3D ant imaging database built with synchrotron X-ray microtomography, a lu...

29 Apr 36min

The Prometheus Constellation: Dramaturgical and Scientific Analysis of the Physicists in Oppenheimer (EP 39)

The Prometheus Constellation: Dramaturgical and Scientific Analysis of the Physicists in Oppenheimer (EP 39)

Hosted by Lester Nare and Krishna Choudhary, this special episode ranks the 26 scientists shown in Christopher Nolan’s Oppenheimer by one standard only: their contribution to fundamental science. Star...

21 Apr 1h 37min

Harder Than Diamond? The New Hexagonal Diamond Breakthrough (EP 38)

Harder Than Diamond? The New Hexagonal Diamond Breakthrough (EP 38)

Hosted by Lester Nare and Krishna Choudhary, this episode is a deep dive into one of the strangest and most hard-fought materials science stories in decades: the claim that researchers have finally sy...

15 Apr 57min

Artemis II: Deep Dive on the Moon Flyby, Earthset, and Reentry (EP 37)

Artemis II: Deep Dive on the Moon Flyby, Earthset, and Reentry (EP 37)

Hosted by Lester Nare and Krishna Choudhary, this episode is a full deep dive on Artemis II as the crew returns from humanity’s first crewed lunar flyby in more than 50 years. Lester and Krishna break...

9 Apr 1h 25min

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