Immune 53: Dendritic cell robbers
Immune reveals that marginal zone B cells steal complexes of MHC and complement C3 from dendritic cells for antigen presentation to T cells. Hosts: Vincent Racaniello, Cynthia Leifer, and Brianne Bark...
21 Feb 20221h 20min
Immune 52: B cell boot camp with Gabriel Victora
Gabriel Victora joins Immune to review how high affinity antibodies are produced in the germinal centers of secondary lymphoid tissues. Hosts: Vincent Racaniello, Stephanie Langel, Cynthia Leifer, and...
29 Jan 20221h 13min
Immune 51: Teenage NINJA mice with Nikhil Joshi
Nikhil Joshi joins Immune to discuss the creation of NINJA mice that synthesize neoantigens to enable the study of endogenous antigen-specific naïve T cell responses in disease and infection. Hosts: V...
22 Dec 20211h 3min
Immune 50: Red blood cells are immune sentinels
Immune reviews evidence that toll-like receptor 9 on the surface of red blood cells binds DNA, leading to uptake by macrophages and innate immune activation. Hosts: Vincent Racaniello, Stephanie Lange...
11 Nov 20211h 21min
Immune 49: I fell in love with worms with Keke Fairfax
Keke Fairfax joins Immune to discuss the work from her laboratory on understanding how maternal schistosomiasis impairs IL-4 production and B cell expansion in offspring, and modulation of macrophage ...
13 Okt 20211h 34min
Immune 48: Environmental enteric dysfunction with Timothy Hand
Tim Hand joins Immune to discuss the work from his laboratory showing that environmental enteric dysfunction, a disease caused by chronic malnutrition and infection, and which is associated with reduc...
13 Sep 20211h 14min
Immune 47: Trapping viruses in NETs
The immune professors discuss neutrophil extracellular traps, and how IgA-virus immune complexes potentiate this process through Fc receptors on neutrophils. Hosts: Vincent Racaniello, Stephanie Lange...
23 Aug 20211h 10min
Immune 46: Bats don't STING like a bee
Immune explore the observation that bat cells display dampened STING-dependent interferon activation, suggesting why bats might have a unique capacity to harbor many viruses. Hosts: Vincent Racaniello...
27 Juli 20211h 10min
