Acute Kidney Injury Caused by Proton Pump Inhibitors
Proton pump inhibitors are among the most commonly used medicines by patients. They're generally safe, but they can cause acute kidney injury, and it's important for clinicians to be aware of this pot...
8 Juli 20209min
Diagnosis and Management of Amyloidosis
Although there are only about 4000 new cases of amyloidosis in the US per year, it can cause preserved ejection fraction heart failure, kidney and liver failure, and neuropathy. Amyloidosis is easily ...
7 Juli 202028min
A Clinical Pharmacologist's Perspective on Penicillin Allergy
Although frequently reported, penicillin allergy is actually uncommon. Penicillins are very effective against a wide variety of infections, and when they can't be used, problems arise. We discussed th...
6 Juli 202018min
Sample Size Calculation for a Hypothesis Test
One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, profes...
2 Juli 202012min
Understanding Pragmatic Trials
Generalizability of randomized trials is always limited because of the super-selectivity of the patients enrolled in these trials and the very controlled conditions in which clinical care is delivered...
25 Juni 202022min
Overview of Depression
Nearly 10% of all patients seen in primary care have depression. Although usually mild, when depression is severe the consequences can be serious. Tom Garrick, MD, professor of Psychiatry at the Unive...
2 Juni 202031min
The Effect of Hearing Loss on Cognitive Decline
Even limited hearing loss might be associated with cognitive decline. If true, early intervention with hearing aids might help people have better cognitive performance. Michael Johns III, MD, online e...
19 Maj 202018min
My Father Was Murdered by Terrorists: Recollections of a Trauma Surgeon
When she was a teenager Melissa Red Hoffman's father was killed by terrorists. Dr Hoffman recalls her father's death and how that has influenced her career and how she can identify with patients and t...
5 Maj 202016min
