LONGEVITY with Nathalie Niddam

Welcome back to the Longevity Podcast! I’m so excited for today’s episode, where I sit down with Chris Rhodes—nutritional biochemist, fasting researcher, and CEO of Mimio Health—to dive deep into one of the most fascinating emerging topics in longevity science: fasting mimetics. If you’ve ever wanted to get the regenerative, anti-inflammatory, and health-boosting effects of fasting, but struggled to actually fast for 36 hours or more (trust me, I get it!), this conversation is for you. Listeners of this podcast can visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order.   What we discuss: Meet Chris Rhodes and his biomimetic research journey ... 00:05:18 Unlocking fasting benefits without prolonged fasting ... 00:09:10 Supplements vs. pharmaceuticals for longevity ... 00:10:53 Fasting protocols, timing, and metabolic switching ... 00:15:23 Risks of fasting, evolutionary adaptation, and muscle/bone loss ... 00:18:34 Ketones, brain energy, and cognitive adaptation ... 00:22:48 How fasting activates longevity and repair pathways ... 00:26:23 Key cellular pathways: AMPK, mTOR, NAD, sirtuins ... 00:28:04 Mimio research: discovering and testing fasting metabolites ... 00:33:35 The four main fasting mimetic molecules explained ... 00:42:04 Practical benefits: who should use fasting mimetics & safety ... 00:59:00 Mimio in use: hunger control, GLP-1 support, and older adults ... 01:03:37   Our Amazing Sponsors: Qualia NAD+ - This vital molecule powers cellular energy, supports DNA health, aids detox, and helps keep your body remain youthful. Visit qualialife.com/nathalie to try Qualia NAD+, backed by a 100-day money-back guarantee, and use promo code NATHALIE for 15% off! OraltidePro - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. Check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order. Bio-Shield by Young Goose - A broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer.     More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

10 Juni 1h 20min

Welcome back to the Longevity Podcast! I’m your host, Nathalie Niddam—nutritionist, human potential and epigenetic coach, and I’m excited to share another solo episode with you. Today, I’m diving into a topic that really resonated with my community on Instagram: five essential habits I wish everyone in their 40s (and honestly, any age!) knew to set themselves up for better health and longevity—without spending a dime.   Resources from the episode: • Grounding – The universal anti-inflammatory remedy • Associations between bedtime eating or drinking, sleep duration and wake after sleep onset: findings from the American time use survey • Meal Timing and Anthropometric and Metabolic Outcomes • Meal Timing, Aging, and Metabolic Health • Obstructive sleep apnea and neurodegenerative diseases: A bidirectional relation • Investigation on the Effect of Oral Breathing on Cognitive Activity Using Functional Brain Imaging   What we discuss: Digestive bitters before meals: benefits and how to use ... 00:02:10 Digestive bitters: impact on digestion, absorption, and immune system ... 00:04:01 Digestive bitters: sources, supplements, and usage tips ... 00:08:17 Training your glymphatic system for brain health ... 00:09:12 Tips to support glymphatic drainage: sleep, exercise, hydration, nutrition, sleep position ... 00:10:19 Grounding: definition, science, and health impact ... 00:13:39 How to ground in urban environments; grounding sheets and tools ... 00:17:08 Eating dinner three hours before bed: why and how ... 00:19:02 Early dinner vs. skipping breakfast for metabolic health ... 00:21:36 Circadian rhythm alignment tips and jet lag hacks ... 00:24:05 Nasal breathing vs. mouth breathing: importance and intro to solutions ... 00:24:36 Mouth breathing risks, sleep apnea, and cognitive implications ... 00:26:52 Practical tools and professionals for correcting mouth breathing ... 00:29:12 Summary of the five key longevity tips ... 00:31:59   Our Amazing Sponsors: MitoBlue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically—Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

6 Juni 33min

I had the chance to sit down with one of the original pioneers of the biohacking movement: Dave Asprey. You probably know Dave as the founder of Bulletproof, the mastermind behind putting butter in coffee, and the creator of Upgrade Labs and the Biohacking Conference. He’s also a four-time New York Times bestselling author.   What we discuss: Biohacking’s relationship with longevity and functional medicine ... 00:10:47 The importance of energy, joy, and personalization in longevity ... 00:14:28 Democratizing lab tests and health optimization with AXO Health ... 00:24:00 Most common health imbalances: thyroid, hormones, minerals ... 00:33:25 Danger Coffee and foundational supplement protocols ... 00:39:43 Pitfalls of oversimplification in health and biohacking ... 00:45:52 Making advanced therapies and tech more accessible ... 00:53:23 Ethical and societal considerations in radical longevity ... 01:07:00 Where to find Dave Asprey and closing remarks ... 01:11:58   Our Amazing Sponsors: Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you’re eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It’s about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you’d get from a glass of pomegranate juice. Visit shop.timeline.com/NAT10 and use code NAT10 for 10% off.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

3 Juni 1h 11min

I’m joined today by Oliver Amdrup-Chamby, the co-founder of Puori and a true trailblazer in supplement transparency and quality. We break down everything you need to know to become a more informed consumer, from how to avoid hidden contaminants like heavy metals, pesticides, and microplastics, to why oxidation in fish oil is such a big deal, and the real story behind protein powders—especially the plant-based ones. Listeners of this podcast get 20% off of Puori protein, a one-time purchase or if you choose the already discounted subscription, you get almost a third off the price! Visit Puori.com/NAT and use my promo code NAT.   What we discuss: Supplements: contamination, purity, and Danish regulation ... 00:08:46 Fish oil: contaminants, microplastics, and oxidation ... 00:12:37 Fish oil quality: what to look for ... 00:15:19 Protein needs, trends, and bioavailability ... 00:24:08 Whey protein vs. plant protein ... 00:27:30 Making protein accessible for families ... 00:31:56 Heavy metals in protein powders ... 00:37:04 Sourcing and batch-level testing ... 00:41:19 Flavorings, sweeteners, and ingredient transparency ... 00:52:10 Tips for selecting clean protein and fish oil ... 01:07:36 Encouraging transparency and consumer advocacy ... 01:11:14   Our Amazing Sponsors: Profound Health -  - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Whatever your health needs, there’s a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. CAROL Bike - With its cutting-edge, science-backed method, CAROL Bike can boost your VO2max by 12% in just 8 weeks—essentially rewinding your fitness clock by a decade. The folks at CAROL Bike are offering a 100-day FREE trial! Visit http://carolbike.pxf.io/Nat or use code NAT100 for a free 100-day trial. Quantum Upgrade - Imagine plugging yourself into a limitless power source. It’s been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use my code NAT15 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

30 Maj 1h 12min

Today, I’m joined by Teo Soleymani, MD—a double board-certified dermatologist, fellowship-trained Mohs and facial reconstructive surgeon, and an expert in all things skin cancer—plus, he’s as entertaining as he is knowledgeable. If you’ve ever wondered whether you should slather on sunscreen religiously, or if embracing more sunlight is actually good for you, we’re here to offer the clarity and nuance that’s so often missing from the conversation. Listeners of this podcast can receive 15% off of SunPowder when you go to sunpowder.co/discount/NAT15 (it’s .co not .com or else you won’t find it).   What we discuss: Sun exposure: fear vs. benefits debate ... 00:06:38 Genetics vs. sun in driving skin cancer risk ... 00:09:04 Types of skin cancer explained ... 00:10:38 HPV, environmental toxins, and non-UV causes ... 00:22:35 Burning vs. safe sun—practical advice ... 00:21:24 Sunscreen: mineral vs. chemical, what matters ... 00:36:01 Problems with spray sunscreens ... 00:40:45 Melanin, UV damage, and skin aging ... 00:13:40 Melasma: hormones and stubborn pigmentation ... 00:47:19 Estrogen, collagen, and topical supplements ... 00:49:18 Astaxanthin and polypodium—internal sun protection ... 00:56:01 Nicotinamide: strong evidence for cancer prevention ... 01:04:11 Sunpowder supplement: trials and benefits ... 01:07:43 Laser resurfacing and reduced cancer risk ... 01:12:33 Genetics, immune health, and testing limits ... 01:15:31 Where to find Sunpowder + connect with Teo ... 01:18:53   Our Amazing Sponsors: LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 20% off your order. Qualia - Senolytic - Clinically tested formula with 9 plant-based, vegan ingredients designed to help your body clear out zombie cells—so you can feel younger, faster. Visit qualialife.com/nathalie and use promo code NATHALIE to save 15% Young Goose L.A.D.R. Serum -  Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Future-proof your face.   More from Nat:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group   More from Teo Soleymani: Website: www.californiadermatology.com and https://sunpowder.co/discount/NAT15 Instagram: @teosoleymanimd Instagram: @drinksunpowder

27 Maj 1h 20min

In this special solo episode, it’s just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I’m shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties.   What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00   Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That’s crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.   More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

23 Maj 32min

Today, I’m joined by Cynthia Thurlow, a remarkable nurse practitioner, podcast host, and true hormone whisperer who is on a mission to help women thrive through perimenopause and beyond.   What We Discuss: Perimenopause, menopause, and longevity connection ... 00:06:09 Hormone misunderstandings and HRT discussion ... 00:07:34 Cynthia’s clinical experience and women's health ... 00:07:53 Recognizing hormonal imbalances and PCOS in young women ... 00:12:09 Autoimmunity risks and thyroid issues ... 00:19:55 Lifestyle factors: aging, processed food, and alcohol ... 00:24:02 Fasting, digestive rest, and metabolic flexibility ... 00:35:02 Practical fasting tips for different age groups ... 00:36:38 Diet flexibility and protein-forward meals ... 00:41:26 Meal timing, circadian rhythm, and satiety ... 00:56:04 Muscle loss, strength training, and optimal protein ... 01:00:36 Gut microbiome recovery and dietary diversity ... 01:06:15 Creatine: benefits, dosing, and sourcing ... 01:08:36 Where to find Cynthia and her products ... 01:15:30   Thank You To Our Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today.  BEAM - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that’s now one of the most mineral-dense substances on earth. That’s what’s going into your body—and your cells absorb it within minutes. Visit https://www.beamminerals.com/NAT20 and use code NAT20 for 20% off.  Wizard Sciences - Mitoblue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   Learn more from Cynthia Thurlow: Website Twitter Instagram Facebook LinkedIn  Youtube   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

20 Maj 1h 17min

Today, I’m joined by Ulrich Dempfle, the innovative mind behind the CAROL Bike. Ulrich’s journey is fascinating—he started as a mechanical engineer in Europe, became a pioneer in hospital AI systems, and is now laser-focused on bringing cutting-edge fitness tech to regular people, like you and me.   What we discuss: Zone 2 training: hype, benefits, and limitations ... 00:08:00 VO2 max: definition and importance for longevity ... 00:10:00 The impracticality and issues with Zone 2 for most people ... 00:15:00 Downsides of long-duration steady-state cardio ... 00:18:00 Why strength and mobility also matter ... 00:17:00 Carol Bike and REHIT: efficient fitness for longevity ... 00:31:00 REHIT’s proven VO2 max and metabolic improvements ... 00:36:00 Personalization and ease-of-use with Carol Bike ... 00:49:00 Carol Bike’s versatility: multiple workouts and app integrations ... 00:57:00 Who Carol Bike is for and safety notes ... 01:10:00 Carol Bike trial info, research, and closing ... 01:12:00   Our Amazing Sponsors: Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Try it for yourself at  troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there. Timeline: Mitopure®️ is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10. Profound Health - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Whatever your health needs, there’s a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

16 Maj 1h 16min