Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects
Interest is growing in the use of the psychedelic drug LSD for psychiatric research and even potentially for treatment. But placebo-controlled studies conducted to date have used just one dose of the ...
19 Jan 20219min
Big behavior: challenges and opportunities in a new era of deep behavior profiling
Scientists who study neuropsychiatric conditions and treatments often use rodent models to do so. From depression to anxiety to memory impairment and impulsivity, there are certain rodent behaviors th...
4 Nov 20209min
Leveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders
The application of the study of genetics and the use of big data to identify patterns of inheritance as well as de novo mutations has had a dramatic impact on the field of Autism Spectrum Disorder res...
23 Sep 20209min
Pubertal adversity alters chromatin dynamics and stress circuitry in the pregnant brain
It’s understood in epidemiological research that women who experience trauma during puberty are at significantly higher risk for affective disorders such as depression and anxiety when they become pre...
10 Juli 20209min
Social networking and mental health: looking beyond frequency of use and towards mechanisms of action
Over the past decades, there’s clearly been a dramatic increase in the amount of time people spend online using social networking sites. For instance, Facebook and Instagram have literally billions of...
15 Maj 20209min
Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects
A number of drugs that are used recreationally are now being studied for their use in psychopharmacology. But while the ways in which these drugs are similar or different has been described anecdotall...
6 Mars 20209min
Chronic opioid pretreatment potentiates the sensitization of fear learning by trauma
It’s known that there’s a relationship between post-traumatic stress disorder, or PTSD, and a higher rate of opioid abuse. What isn’t understood, though, is what that relationship is. Does PTSD cause ...
17 Jan 20209min
Effects of MDMA on attention to positive social cues and pleasantness of affective touch.
The recreational drug MDMA, also known as Ecstasy or Molly, is particularly popular in social settings and raves, in large part because of how socially connected it makes the users feel. It's being st...
19 Sep 20199min
