JALA June 2013 Podcast: Automated Operation of Immiscible Filtration Assisted by Surface Tension (IFAST) Arrays for Streamlined Analyte Isolation
The extraction of specific analytes from biological samples is a ubiquitous process spanning many areas within the life sciences.
29 Apr 201310min
JALA April 2013 Podcast: Automated Rotation Rate Tracking of Pigmented Cells by a Customized Block-Matching Algorithm
The authors preprocess each frame of a video sequence, then analyze the sequence frame by frame using a rotating-circle template with a block-matching algorithm, and estimate the rotation rate of the ...
19 Feb 201315min
JALA June 2012 Podcast: Automation of Cell-Based Drug Absorption Assays in 96-Well Format Using Permeable Support Systems
Cell-based drug absorption assays are an essential component of ADME/Tox testing for lead compounds. In this report, Apparent Permeability (Papp) and Efflux data demonstrate how an automated procedure...
8 Feb 20130s
JALA February 2013 Podcast: Reversible Regulation of Aptamer Activity with Effector-Responsive Hairpin Oligonucleotides
Aptamers are oligonucleotides that can bind to various nonnucleic acid molecular targets in a high affinity and specificity. As an emerging class of therapeutic agents, aptamers offer an unparalleled ...
19 Dec 201213min
JALA December 2012 Podcast: The First 110 Years of Laboratory Automation: Technologies, Applications and the Creative Scientist
JALA celebrates part two of its two-part special issue on Robotics in Laboratory Automation by discussing one author's historical perspective on the genesis of today's automated laboratory.
2 Nov 201211min
JALA October 2012 Podcast: A Serial Sample Loading System: Interfacing Multiwell Plates with Microfluidic Devices
The application of a positive pressure based Serial Sample Loading (SSL) system to load the series of sample plugs into the capillary is demonstrated along with the adaptability of the SSL system to g...
21 Aug 201210min
JALA August 2012 Podcast: Performance Evaluation of 3D Polystyrene 96-Well Plates with Human Neural Stem Cells in a Calcium Assay
An HTS compatible 3D cell culture platform is generated by chemically “welding” polystyrene scaffolds into standard 2D polystyrene 96-well plates. The variability of scaffolds is minimized by introduc...
12 Juli 201214min
JALA June 2012 Podast: Automation of Cell-Based Drug Absorption Assays in 96-Well Format Using Permeable Support Systems
In this report, Apparent Permeability (Papp) and Efflux data demonstrate how an automated procedure, when compared to manual processing, provides a method that is less variable and is capable of deliv...
17 Maj 201233min
