S5 - E12.2 - MASH Drug Development: Improving Efficacy Endpoints
Send us Fan Mail In this conversation, the panel discusses challenges in MASH Drug Development that are centered around efficacy endpoints and NAS scoring. This conversation starts with Will Alazawi ...
27 Apr 202412min
S5 - E12.1 - MASH Drug Development: The State Of The Graveyard 2023
Send us Fan Mail In this initial conversation, Sven Francque shares some of the key messages from the MASH Drug Development graveyard paper he co-authored in 2023. Jörn Schattenberg and Will Alazawi c...
27 Apr 202411min
S5 - E12 - MASH Drug Development: What Failures Taught Us About Success
Send us Fan Mail In this conversation, Sven Francque and William Alazawi join Jörn Schattenberg, Louise Campbell, and Roger Green to review papers co-authored by Sven in 2023 and Jörn in 2020 to discu...
25 Apr 202454min
S5 - E11.6 - From The Vault: Another Strategic Role For Prescribing MASH Drugs
Send us Fan Mail Earlier in this episode, the panel discusses different prescribing models for MASH drugs, triggered by Roger Green's question about whether MASH prescribing will resemble an oncology ...
21 Apr 202411min
S5 - E11.5 - MASH Prescribing Models & The Increasing Challenge Of Keeping Patients In Long-Term Clinical Trials
Send us Fan Mail This final conversation starts by considering prescribing models for other diseases and how they might work here, shifts to discussing the challenges of keeping a patient enrolled in ...
21 Apr 202410min
S5 - E11.4 - More Hot MASLD Topics: Inflammation, MD columnists' Advice, FGF-21s
Send us Fan Mail This conversation sees the end of the "hot topics" discussion, followed by Michael Charlton discussing issues and excitement around the FGF-21 class. As we begin, Louise Campbell and...
21 Apr 202410min
S5 - E11.3 - Panelists' Hot Topics: Low-Dose Aspirin, SLD Think Tank, Dietary Inflammation Index
Send us Fan Mail After Michael Charlton finishes discussing research he finds compelling, Jörn Schattenberg and Louise Campbell each describe one item they have been focusing on recently. Michael me...
20 Apr 202413min
S5 - E11.2 - Defining Therapeutic Futility For Rezdiffra And Discussing Advances In MASLD Translational Medicine
Send us Fan Mail Michael Charlton and the Surfers discuss two issues: defining therapeutic futility for Rezdiffra and describing some advances in MASLD translational medicine. The conversation start...
20 Apr 202411min
