The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Here's Why You Still Feel Like Sh*t After Doing Everything Right...  : 1434

Here's Why You Still Feel Like Sh*t After Doing Everything Right... : 1434

Your thyroid controls your energy, your metabolism, your testosterone, your mood, and your ability to think clearly. Most doctors are testing it wrong and treating it wrong, and this episode tells you...

19 Mars 1h 1min

The Awakening Within Cells: Healing Breakthroughs No One Can Ignore : 1433

The Awakening Within Cells: Healing Breakthroughs No One Can Ignore : 1433

What if a glowing pyramid sitting in your living room could restructure your biology, compress decades of meditation into minutes, and shift your brain into an altered state without drugs, breathwork,...

17 Mars 58min

This Nobel Prize Discovery Reverses Aging In 72 Hours : 1432

This Nobel Prize Discovery Reverses Aging In 72 Hours : 1432

Is aging an inevitable decline, or just a "repair backlog" your body hasn't cleared yet?. In this episode, Dave breaks down the 2016 Nobel Prize-winning science of autophagy—the body's internal recycl...

15 Mars 16min

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431

This week’s stories: Smartphone App Catches What Sleep Trackers Miss A 2026 trial found that suvorexant, a popular prescription sleep drug, improves sleep quality scores — but worsens morning alertnes...

13 Mars 12min

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it. -Watch this episode on YouTube for the full video experience: h...

12 Mars 1h 3min

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

What if understanding how AI thinks could reveal uncomfortable truths about how your own brain works, and give you powerful tools to make smarter decisions, resist manipulation, and upgrade your cogni...

10 Mars 57min

How I Finally FIXED My Terrible Sleep After 18 Years  : 1428

How I Finally FIXED My Terrible Sleep After 18 Years : 1428

Block toxic light with these glasses: https://truedark.com/discount/DAVETUBEThink 8 hours of sleep is enough? Think again. I used to think I had a sleep issue—turns out, it was a light issue. In this ...

8 Mars 9min

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

This week’s stories: Healthy Diets That Offset "Bad Genes" A major UK Biobank study of over 100,000 people found that following any one of five healthy dietary patterns was associated with up to 3 ext...

6 Mars 11min

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