193: Persisters
The TWiM team explore how Lactobacillus reuteri can rescue social deficits in three mouse models of autism spectrum disorder, and the role of Salmonella persisters in undermining host defenses during ...
31 Jan 20191h
192: A Qtip for phages
The TWiM team reveals an extremely low rate of mutation in a 2500 year old, 185 acre fungus in Michigan, and how a host-produced quorum sensing autoinducer controls the phage switch between lysis and ...
18 Jan 20191h 6min
191: By the pulp of their teeth
The TWiM team reveals the oldest human plague from 4,900 years ago in Sweden, and engineering E. coli to become an endosymbiont in yeast, modeling the evolution of mitochondria. Hosts: Vincent Racanie...
21 Dec 20181h 1min
190: Exosomes in your nose and in your gut
The TWiM-opods consider two stories about exosomes, vesicles that are shed from cells: those that eliminate airway pathogens, and those from the plants we eat that shape our gut microbiome. Hosts: Vi...
7 Dec 20181h 18min
189: Salmonella BonJovi
The TWiM team considers the state of the world's fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses. Hosts: Vincent Racaniello...
16 Nov 20181h 11min
188: Turducken antibiotics
The TWiM rock stars show how to modify gram-positive antibiotics so they can kill gram-negative cells, and bacteria that have both DNA and RNA in their genome. Hosts: Vincent Racaniello and Michael Sc...
31 Okt 20181h 20min
187: Rounding up the bees
The TWiM people reveal that phages must cooperate to overcome CRISPR-Cas defenses, and the effect of the herbicide glyphosate on the gut microbiome of honey bees. Hosts: Vincent Racaniello, Elio Schae...
19 Okt 20181h 6min
186: Crypto-metamorphosis
The TWiM team describe the involvement of a microbiome in snail metamorphosis, and using Listeria to kill tumors. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (fr...
5 Okt 20181h 13min
