Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed

In our last episode, we met Emily who was dealing with fatigue, brain fog, dry mouth, bad breath and problems with her gut health. We discovered that the root cause of her health issues was in her mouth - namely that she was suffering from undetected infections and was experiencing Mercury leaching from her silver amalgam fillings. Dealing with this root cause carefully while supporting her immune health resulted in a massive improvement in her day-to-day well-being. Plus, she even reduced her Hashimoto’s antibodies significantly!     If you missed that surprising episode - listen to it here.    The Investigation Helping me out with the last case was dentist to the stars, Dr. Kourosh Maddahi. Our conversation went well beyond the dangers of mercury fillings and hidden dental infections. We also talked in depth about the importance of paying attention to the microbiome of your mouth (yes, your mouth - it’s not just your gut that has a microbiome!) That conversation was so important that I wanted to make sure to share it with you. So, this week, we are continuing our conversation about obtaining optimal dental health to support your overall well-being.    How Food Impacts our Dental Health Most of us know that sugar can cause tooth decay, but Dr. Maddahi says that our diet has a bigger impact on our oral health than this. He believes that pesticides we ingest (when we are not eating organic food, for example) can seriously impact our mouth’s natural biome.  The Microbiome of the Mouth When people hear ‘microbiome’ chances are their thoughts go to the gut. It’s what we talk about the most! But, your body has other biomes including a delicate one in the mouth. And, like the one in your gut, the mouth needs both good and bad bacteria to balance out to optimal. Dr. Maddahi says that the mouth’s microbiome has been under attack with the increasing focus on eradicating all bacteria in the mouth. Mouthwashes, sprays, toothpastes all promote being anti-bacteria (usually in their promise to get rid of bad breath). However, these products don’t just kill the bad bacteria, they kill the good bacteria too, leaving the cells in the mouth unprotected and the mouth’s microbiome in an unhealthy state.  In addition, the body requires certain bacteria to stimulate the creation of certain vitamins. For example, it’s required for the production of Vitamin K. Without proper levels of vitamin K, blood may not coagulate properly.    Digestion Starts in the Mouth When we think about digestive issues, we don’t often think about where the process starts. In order to digest our food properly, we have to first chew it properly. We also need a healthy mouth biome for the food to start breaking down. The gut has 144 strains of microbiome and about half of those are also found in the mouth. So, the process of digesting our food really does start in the mouth.    Dry Mouth Can Cause Big Problems Saliva is a part of the defense mechanism in the mouth as a natural antibiotic. It plays a role in maintaining a healthy microbiome. However, there are over 450 medications that cause dry mouth. This is more than a discomfort. Dry mouth increases the chances of cavities. Without sufficient saliva, these cavities can develop very quickly - even with good oral hygiene.     Maintaining Healthy Microbiome in the Mouth Ninety-eight percent of the bacteria in your mouth is good bacteria. However, that percentage can fluctuate when bad bacteria spikes. These spikes are caused by things like eating sugar, nutrition, not cleaning the mouth regularly and allowing plaque to harden on the teeth. The fear of bad mouth bacteria causes some people to reach for an antiseptic mouthwash. While these products do kill the 2% of bad bacteria, they also kill off the 98% of bacteria that’s good - the bacteria that’s protecting your mouth (and your gut).  It’s much better to avoid sugar, toxins, and practice good dental hygiene to control the bad bacteria.    Brushing Your Teeth Properly Brushing and flossing regularly is key to removing plaque before it can harden on the teeth. However, Dr. Maddahi says that most people are doing it wrong. In fact, he says improper brushing or use of the wrong kind of toothbrush causes 50% of the recessive gums he sees in his practice. Toothbrushes should have soft bristles otherwise, it will damage the gums. He also says that you should not be scrubbing your teeth or going back and forth with the brush because it can damage the gums and remove important tooth enamel. Instead, he recommends holding the toothbrush at a 45°, starting at the gum level and brushing down (or up for the bottom teeth) followed by a very gentle circular motion to remove plaque. If using an electric toothbrush, don’t use it the same way you would a manual toothbrush; let the mechanics do the work instead.   Select a Non-Toxic Toothpaste Dr. Maddahi says that it’s important to select a toothpaste that is not going to disrupt the balance of your mouth’s microbiome and that is not going to introduce toxins. He has developed a dental care product line that naturally neutralizes the toxins and bad bacteria without destroying the good bacteria. Dr. Maddahi has created a natural tooth-care product line called Oral Essentials that he says is proven effective in 51 clinical research studies. There are a variety of products including one for whitening (without the enamel damaging peroxide) and one for kids.    Conclusion After my conversation with Dr. Maddahi, I changed the way I brushed my teeth and was inspired to try the Oral Essentials. We can’t take our teeth for granted but there is so much more to caring for them than just making sure they are sparkling white. Since the mouth is the gateway to our guts, how well we take care of it will directly affect our gut-health which we know is so central to good health.    Eliminating Health Mysteries Could a simple change to your oral health practices have a big impact on your overall health? There are so many health mysteries that could be caused by the microbiome in the mouth.  Could this be the missing clue for you or someone in your life?    Links: Resources mentioned Thanks to my guest, Dr. Kourosh Maddahi. You can connect with him through his website or on Instagram. You can also check out his line of natural dental care products - Oral Essentials here and make sure you use the promo code INNA15 to save 15%!    Suggested Products OralEssentials.com (save 15% with promo code: INNA15)   Related Podcast Episodes: The Case of Mercury Fillings w/ Dr. Kourosh Maddahi The Case of Tooth Pain Causing Fatigue with Naturopath Dr. Christine Shaffner   Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts,

6 Aug 202038min

The Case:  Emily is 45 dealing with fatigue, brain fog and digestive issues as well as dry mouth and bad breath. Her doctor’s diagnosed her with Crohn’s Disease and Hashimoto’s but that alone didn’t help her symptoms.   She tried changing her diet, took supplements and brushed her teeth after every meal.    The Investigation My investigation started by looking into Emily’s dry mouth and bad breath. Her oral health was quite poor despite frequent brushing and I noted that she’d had several root canals and many silver fillings. I know this was going to be a key piece in solving her health mystery because even though these may not seem related, everything in the body is connected.  “Silver fillings” or Amalgam fillings are actually about 54% elemental mercury and mercury can cause all kinds of health issues. On top of that, our oral health can seriously impact our overall health, even when we think we are practicing good oral hygiene. Dr. Kourosh Maddahi is a dentist to the stars, the author of 'Anti-Aging Dentistry' and the founder of the research-based Lumineux Oral Essentials. He joins me in this episode to shed some light on what might be going on with Emily.    Your Mouth is a Gateway to Your Body The mouth is the first entry point for the digestive system with regards to disease or infection. The mouth is the most vascular area which means that it is easy for bad bacteria and viruses to be transmitted through the mouth vascularly as well as by swallowing.  We know that chronic inflammation is a key component in many diseases and the mouth is also susceptible to inflammation. Gingivitis, for example, is chronic inflammation of the gums. This inflammation can increase the chances of transmitting disease because swollen gums are more likely to have tiny cuts (and bleed) which removes the barrier between bad bacteria or viruses and the bloodstream.    Signs of Inflammation in the Mouth  The first and most common sign of acute or chronic inflammation is bleeding during or after teeth-brushing. A second sign is if there is discomfort when eating, especially if there is pain when biting or chewing. Pain during eating can be a sign that there is an infection under the tooth, in the gums, or in the bone. Dentists can do X-rays and probe the gums to confirm chronic inflammation and/or a suspected infection.    Causes of Inflammation in the Mouth & How to Avoid It Inflammation can happen quickly. For example, Dr. Maddahi says that a build up of hardened plaque causes inflammation and plaque can harden on your teeth within 24 hours. That’s why brushing frequently is so important. He says the simplest way to avoid inflammation is to remove plaque before it can harden - in other words, floss and brush regularly and see your dentist to remove hardened plaque every 6-months.    Health Risks from Silver Fillings (Amalgam Fillings)  Silver fillings contain mercury which is known to cause health issues. Mercury exists in three forms: solid, liquid, and vapor. The vapor form is the greatest concern in the mouth because it can leach out when we are chewing or drinking hot liquids and enter various tissues and organs. Of particular concern is that mercury vapor can break the blood-brain barrier and the half-life of mercury in the brain is 20-years. As mercury accumulates in organs, it can reach toxic levels. Mercury toxicity can impact the nervous, digestive and immune systems. It can also negatively affect the development of children in utero and in early life.    Testing for Mercury Toxicity Common practice is to test your hair and urine to determine mercury levels in the body. However, Dr. Maddahi says this is not a true indication because the mercury could be absorbed in the tissues and organs. Instead, he suggests doing a challenge test.    Should You Remove Mercury Fillings? This is a controversial question for a lot of dentists and health experts. While it may seem like an obvious solution, given the leaching of mercury vapors into our system, the drilling and removal of silver amalgam fillings can cause a significant release of vapors - as much as 100 times more than the you might experience by not removing them - during a very short time period. If the patient is healthy and doing the removal as a precaution, then Dr. Maddahi suggests only doing one quadrant at a time.   Safety During the Removal of Mercury Fillings Anyone choosing to remove mercury fillings should select a dentist who will take the greatest precautions to reduce the potential exposure to mercury vapors. For example, the patient should be on oxygen so that they are breathing through their nose and not through their mouth during the removal. There should also be a vacuum to capture the filings and aerosol caused by the drilling. And, Dr. Maddahi also gives patients an activated charcoal rinse to coat the gums and stomach which reduces the chances of mercury being absorbed.    What is Biocompatibility Dentistry?  Biocompatibility Dentistry is the matching of dental products to the individual based on sensitivities they may unknowingly have. This process involves doing a Clifford Test prior to dental work that tests the patient’s blood for incapability issues they may have to certain (commonly used) dental materials. This is really important because without it, a patient may get a crown or a veneer using materials they are incompatible with and constantly have issues with and around that tooth (including discoloration, inflammation, pain, and bleeding).    Detecting Infections in Teeth and the Mouth Aside from mercury fillings, there is another hidden dental issue that can impact overall health - infected teeth or bones in the mouth. Infections can happen inside teeth - especially in the case of a poorly-done root canal. Dr. Maddahi says that these infections have been linked to immunity issues. Detecting this kind of infection can be done using an X-ray or, in some cases, a cone beam scan. Another source of infection is through cavitations in the bone caused by the removal of a tooth. A scan can also help with detecting this.  Mystery Solved The first step in solving Emily’s health mystery was for her to see a biological dentist and get some good scans to determine if infections or cavitations may be the culprit. And, to discuss whether removing her silver amalgam fillings might be beneficial. This visit revealed a lot!  While she worked closely with this dentist to address all those issues, I supported her detox pathways with glutathione and binders to make sure she was not absorbing any of the toxins that were being removed from her mouth.  Emily and her dentist took the removal of her silver fillings slow to ensure her body could detox and adjust. She had 10 fillings changed over and had one tooth pulled (a previous root canal had become infected) over the course of 3 months.  In that time, she had no detox reactions and noticed an improvement in her energy and brain fog when all the dental work was done.   While doing the dental work, we also began a cleanse with anti-microbial herbs to deal with several infections that we detected through a stool test. Then we healed her gut and replaced the good bacteria with

30 Juli 202044min

Last week I shared some of the questions you wanted answered about Hashimoto’s. I covered topics like the relationship between heavy metals and Hashimoto’s, the role the adrenals play in Hashimoto’s, the relationship between Epstein-Barr Virus (EBV) and Hashimoto’s and how to reduce the risk for kids of people with Hashimoto’s. All of them were very important questions that have a lot to do with the triggers of Hashimoto’s. If you missed it, here is a link to episode 068.    In this episode, I answer more of your questions about Hashimoto’s.    Question #1: With Hashimoto’s, is TSH a reliable indicator of the body’s thyroid hormone needs? If not, what else can we use to know what the body needs? This can be very confusing for anyone with Hashimoto’s. The short answer is, no. TSH is not a reliable indicator. The ranges  for TSH are very broad (typically between about 4.5 - 5 depending on where you live. This range is not really optimal. The optimal range for TSH is between 1.8-3 (if you’re on thyroid medication this shifts a bit).  But, TSH is only one indicator and you need to look at the big picture including your total T4, free T4, total T3, free T3, and reverse T3. This is because TSH is not actually created in the thyroid - it's the thyroid stimulating hormone created in the pituitary gland. So, only looking at TSH doesn’t tell us which hormones the thyroid is producing and at which ratio. And, it doesn’t tell us how well the body (primarily the liver and the gut) are converting these hormones or how the hormones are actually utilized. Essentially, TSH shows a very very small part of a much bigger picture and that is why its not nearly complete. With Hashimoto’s you also want to track your antibody levels so that you can determine which triggers (listen to episode 068 for more on the four triggers) are affecting you and your levels.  I’ve listed the various tests I recommend to get the whole picture of your thyroid functionality and optimal levels for each in the show notes for episode 027. If you are looking for a lab to do these tests, here is a link to a helpful resource and lab.  I’m in the process of creating my thyroid course which is going to get way more in depth about this and how you can figure out your pattern and exactly what to do about it. The course will launch this fall. Add your name to the wait list if you’d like to be personally invited to join.    Question #2: Why does someone with Hashimoto's feel tired all day long? How can we help this and what can we do to wake up feeling refreshed and have more energy throughout the day? While Hashimoto’s is an issue, we need to look at the root cause of the fatigue. It’s true that Hashimoto’s causes the immune system to attack the thyroid and often causes hypothyroidism which has a common symptom of fatigue. So, the first step is to make sure that you are supporting thyroid function optimally with what your body needs (foods, supplements or if necessary thyroid medication that is dosed appropriately) and you are also by avoiding Hashimoto triggers (noted in last week’s episode). If you are doing these things and continue to feel tired, then you may want to consider the role your adrenal glands may be playing in your fatigue. The adrenals and the thyroid are very interrelated. Stress is a key trigger for Hashimoto’s and it can also impact adrenal function.  Clean eating is also recommended but if you continue to feel tired, you may be having some issues with absorption which could be caused by a gut issue. This could be the real cause of the fatigue as well  And finally, check that you are not deficient in nutrients that help us feel more energized like iron, B12 and other B vitamins.  As you can see, feeling tired is quite multi faceted so we have to look at it from all angles.   Question #3: My diagnosis of Hashimoto's only came after being on thyroid medication for years. Can this medication be contributing to Hashimoto's?  In my opinion, I don’t think it did. What often happens is that the Hashimoto’s is undiagnosed for many years. Conventional doctors will often stop looking for answers once they diagnose hypothyroidism. So, the Hashimoto’s may have been there or been developing all along. I don’t think that the medication could cause Hashimoto’s because whether you’re taking a synthetic hormone or a natural, desiccated hormone, you’re just replacing the hormone that the body is failing to produce. One thing that could be setting off the immune system is a sensitivity to corn. Some medications are made with cornstarch so a small amount, everyday could be causing a reaction from the immune system so that is something to look into and perhaps change to a compounded medication with no fillers can help.   Question #4: Do you have to eat after taking Levothyroxine? And, can it be taken when doing a water-fast? Levothyroxine or L-thyroxine is a T4 medication prescribed to some people with low thyroid function. It is meant to be taken on an empty stomach and you don’t need food later to help it absorb. So, in the case of a water-fast, it should not impact the effectiveness. However, water-fasts should be done under the guidance of a health practitioner so make sure they know you’re taking Levothyroxine.    Question #5: How can you lose (or gain) weight when you have Hashimoto’s I had multiple people ask me about this - both people looking to lose weight and people struggling to maintain or gain weight.  We know that the thyroid has a big effect on metabolism. Once again, it’s important to look at the full hormone picture (not just TSH levels) to determine if the thyroid is not functioning optimally. If everything looks good, then the next place to look is at the food you’re eating - specifically any foods that you may have a sensitivity to. Food sensitivities can cause inflammation resulting in water weight gain. Hormonal imbalances may also be impacting the metabolism.  The other big thing to consider is your metabolic type. We have different metabolic types, some people are protein or fat types and some are carb types. The protein types tend to do better with higher protein and fat whereas the carb types tend to do better with some carbs and less fat. If you are eating counter to your type (even if it’s super healthy) you may struggle to lose or gain weight. Also if you combine too much fat with too many carbs (even if they are good fats and good carbs) that tends to have a negative effect on our metabolism. While calories are not everything, how we combine our food does make a big difference.  For anyone struggling to maintain their weight or gain weight the first thing to check is that you’re not over medicated or over-supplemented. Next, watch for triggers that may be causing Hashimoto’s flare ups. These can send your thyroid into hyper mode and then drop back down to hypo mode. And, like the weight loss issue, make sure you are eating for your metabolic type and for you, combining good carbs with good fats would in this case be a good thing.    Question #6: Does the ketogenic diet help or hurt people with Hashimoto's? There’s a few opinions on this and it depends on how you look at it. W...

23 Juli 202028min

I asked what you wanted to know about Hashimoto’s and the questions came flying in! In this episode, I’m going to tackle half of them and tune in next week as well because I’ll answer the rest there! Hashimoto’s disease is an autoimmune disease that affects the thyroid. Like other autoimmune diseases, what happens is that the immune system gets confused and starts to see the thyroid as a threat. In other autoimmune diseases, the system attacks a different part of the body (the myelin sheath with MS, joints with rheumatoid arthritis, connective tissue with lupus). Under this attack, the thyroid can’t perform optimally and the result is often hypothyroidism.  Conventional medicine treats Hashimoto’s by only addressing the  hypothyroidism if present or waiting for hypothyroidism to begin or suppressing the immune system with medication. The functional medicine approach is to find the root cause of the Hashimoto’s and fix it. I support the functional medicine approach and it starts by understanding what’s going on first. Which is why, I’m so happy to answer your questions!   Autoimmune Triggers  There are four main triggers that can get the immune system in a tizzy. Here are the key triggers for autoimmune diseases: Food Individuals may have food sensitivities, or lack the proper enzymes or stomach bile to properly digest food. If the food we eat doesn't work for our body its a huge trigger for autoimmunity. Infection There are a variety of infections that can become chronic causing the immune system to malfunction. Toxins Environmental toxins (like those found in some cleaning products and beauty products) as well as heavy metals can serve as a trigger. Stress The immune system handles stress by shutting down other non-essential systems. Over time (especially if it’s chronic), this can be a trigger for autoimmune disease.    Question #1: What is the relationship between heavy metals and the root cause of Hashimoto's? Heavy metals are things like aluminum, mercury, arsenic, lead and they can really do a number on our system. Our bodies can handle a little bit of heavy metals but when they build up, they become a toxin (which is one of the triggers). Even copper can become a toxin if it gets out of control (usually due to a zinc deficiency). Mercury has an affinity for the thyroid, so this heavy metal (in particular) should be monitored to ensure it hasn’t reached toxic levels in the body.  There are lab tests that will determine if heavy metals might be the root cause for you. A standard hair analysis is one test but it doesn’t show both types of mercury. My go-to tests for heavy metal are the Quicksilver Scientific Tests because it includes a full heavy metal panel and looks for mercury levels in the blood, urine, and hair.  If heavy metal is a problem, then a detox using binders and herbs like Milk Thistle are often used. However, you’d want to consult with a functional medicine practitioner to make sure you’re doing the right kind of cleanse.   Question #2: What is the connection between Hashimoto’s and the adrenal glands? Stress is one of the four triggers. The adrenal glands deal with stress by producing the hormone cortisol. When too much is produced, the immune system takes that to mean that it’s an emergency putting things like thyroid production on the backburner.  Cortisol also has a relationship with TSH. When cortisol is off, TSH can be off as well and directly affect thyroid function. There is one other potential connection. The symptoms of hypothyroidism are very similar to the symptoms of adrenal fatigue (weight gain, fatigue, depression, hair loss) and so the symptoms may be misinterpreted.    Question #3: What is the true connection to EBV (Epstein-Barr Virus)?  This question sparked a secondary question involving the Medical Medium and the things he’s said about EBV being connected to everything, including attacking the thyroid before causing Hashimoto’s.  I get asked about this a lot but remember the four triggers - one of them is infection which is exactly what EBV is. There is some research that EBV can get into the thyroid gland (as well as other organs) but I wouldn’t say it’s conclusively linked. However, it is an infection which is a trigger. It’s worth noting that once someone gets EBV it’s always in the system and it can flare up due to stress, toxins, and other infections - it has the same triggers as autoimmune.    Question #4: Can you Address Food Sensitivities with Hashimoto’s? Another listener also asked about her experiences with cutting out gluten and dairy and subsequently developed other food sensitivities. (Be sure to check out the episode I did on food sensitivities for more on this)  Food is one of our four triggers, so we know there is a connection. Food sensitivities are not  typically things are born with, they develop over time. So, I  always recommend that you get tested  to see what your sensitivities are using a test that will look comprehensively at antibodies and genetics (not just the general antibody test). But also we want to look at where the sensitivities come from (before eliminating more and more foods) because if there’s inflammation in the body, you're more prone to sensitivities.  Another thing to consider is if you might have gut issues, dysbiosis, candida, parasites or bacteria. This could create a lot of inflammation in the intestines, causing leaky gut. And, if you are lacking the right enzymes or your bile is off, you may not be digesting your food which could result in food getting into your bloodstream. So, sensitivities can definitely be a trigger but you also want to make sure that it’s not your gut health (and infections) causing the issue.    Question #5: Hashimoto’s tends to run in families, especially daughters and females. Is there anything I can do to keep my daughters from getting it down the line? I love this question because there’s so much we can do to protect our children’s health. Prevention is the key when you’re dealing with any disease - especially autoimmunity. Start by considering the four main triggers.  Testing for food sensitivities early can be helpful as can genetic testing - specifically the HLA-DQ2 and HLA-DQ8 which is related to gluten which has a big connection to autoimmunity (not just Hashimoto’s).  Keep an eye on their gut healthy - especially with regards to antibiotics that can disrupt the microbiome and cause dysbiosis (which introduces another trigger - infection).  Consider a good probiotic for kids and doing a regular stool test to get a sense of their microbiome.  Toxins can be minimized by control chemicals in the home (including cleaning products and beauty products). And finally, try to help them learn how to deal with stress. I like the book The Goodnight Caterpillar: A Children's Relaxation Story to Improve Sleep, Manage Stress, Anxiety, Anger by Lori Lite and Emily Fletcher (who appeared on episode 005) has a new meditation program for kids. And, remember that kids learn from watching us, so make sure you model good stress-management skills too.    Next Episode You had more questions about Hashimoto’s disease than I could answer in this one episode! So, tune in next week for more questions and answers about Hashimoto’s and your thyroid he...

16 Juli 202023min

The Case:  Robin is a 45 year old, super-busy, working mom dealing with aches and pains all over. She’s also experiencing stomach aches and unexplained bladder issues that include pain and burning during urination without a detectable UTI. She’s seen specialists, taken antibiotics, and tried eating healthier but her symptoms just got worse.    The Investigation When I hear that a healthy diet makes someone feel worse, I immediately suspect that the food they are choosing, while healthy on the surface, may not be right for them. This was my suspicion with Robin and I knew it could be one or more of a few things in her diet causing the issue.  I’ve been wanting to invite Dr. Beth O’Hara on the show for a while and I knew this case was right up her alley. Dr. O’Hara is a Functional Naturopath and the owner of Mast Cell 360, a Functional practice specializing in root cause approach to Mast Cell Activation Syndrome, Histamine Intolerance, and related conditions such as oxalates, mold toxicity, and chemical sensitivities. She is a Research Adviser for the Nutrigenetic Research Institute and also works in-depth with genetic analysis.   What are Oxalates? Plants are made up of compounds and oxalates are one of these compounds. Under a microscope, oxalates appear to look like tiny razor blades - they are very sharp molecules. Certain plants have a high number of these compounds which serve as a defense mechanism for the plant. Foods that we consider to be very healthy, could be high in oxalates like spinach, beets, rhubarb, sweet potatoes, and almonds. Oxalates can also be created by our bodies and some fungal species may create oxalates in the body. While many people are able to metabolize these compounds without any issue, there are also many that may not.   The Risk of Elevated Oxalates in the Body Some people struggle to process these oxalates and this can be due to many things  and the oxalates build up. The immune system wants to get rid of this excess which results in inflammation. Overtime, this can become chronic and cause other health issues including kidney stones. however  kidney stones are just the tip of the iceberg and oxalates have also been associated with thyroid issues, autism, endometriosis, bladder issues, vulvodynia, PCOS, diverticulosis/diverticulitis, breast cancer, osteopenia and osteoporosis.    Causes of Elevated Oxalates One of the causes of elevated oxalates is eating a diet rich in foods with high levels of oxalates. However, there are plenty of people who eat these foods and don’t have an issue. There are a few other factors that can cause elevated oxalates.    Genetics   There are four genetic predispositions that may make someone more susceptible to developing an issue with oxalates.    Vitamin Deficiency   A deficiency in B1 or B6 can cause an issue with oxalates   Leaky Gut   When there is a break in the intestinal lining, oxalates can move into the bloodstream and to muscles, joints and even bone, potentially causing many issues.   Mold Toxicity in the Body   Exposure to mold can result in that mold colonizing in the body, which demands a lot from the immune system and can make it difficult for the body to deal with oxalates. Additionally, its possible the dysbiotic bugs may produce even more oxalates to add to the load.   Symptoms of Elevated Oxalates Kidney stones are often noted as a key symptom but only 1% of people experience these. More often, it’s seemingly unassociated symptoms that are hard to nail down like fibromyalgia, joint pain, joint issues, visual problems (including cataracts), lung issues (including asthma), vertigo, urinary tract issues (pain and burning during urination as well as urgency that present like UTIs but no infection is present), and vulvodynia (stinging, burning, and irritation of the vulva).    Mast Cell Activation Syndrome Scientists have been studying Mast Cell Activation Syndrome or MCAS since the 90’s but it has only recently (2016) been given a diagnosis code. As a result, many conventional doctors do not know about it. The immune systems ‘front-line defenders’ are known as Mast Cells. It’s their job to recognize a virus, injury, toxin, or bad bacteria that is threatening the body and mount a defence against it (usually causing inflammation to the area) and then signal the immune system to do its job. However, when there is a chronic issue, like elevated oxalates, the Mast Cells become dysregulated, fail to trigger the immune system and cause MCAS. Mast Cell Activation Syndrome affects an estimated 10 - 17% of the general population and is estimated to impact over 50% of those with chronic illness.    MCAS and Elevated Oxalates Oxalates stimulate an enzyme called NOX. The role of this enzyme is to kill off pathogens and stimulate mast cells. When there are elevated levels of oxalates in the body, there is an over stimulation of mast cells which dysregulate over time and triggers MCAS. Oxalates can also cause physical damage on a microscopic level (because they are sharp and can wedge into tissue) which causes further mast cell stimulation.    Diagnosing Elevated Oxalates The key to diagnosing oxalates is to look at the four key causes, starting with a genetic predisposition to hyperoxaluria (high oxalates). There are labs that can do this test and there are four markers to look for:  AGXT (commonly associated with  kidney stones.  SPP1 GRHPR HOGA1 The next step is to test for a vitamin B1 or B6 deficiency and an LDH. And, to make sure a leaky gut or mold toxicity are not issues. Dr. O’Hara likes to use the Great  Plains organic acid test as it has three markers for oxalates. The first two are glycemic and glycolic (related to the  human biochemical pathways involved in oxalate production) and third is oxalic (which will show oxalate from over consumption and it should be around 75). However, that is not going to show any oxalates that have been embedded into tissue or muscle.  Treating Elevated Oxalates Reducing oxalates in the diet is going to provide almost instant relief to symptoms of elevated oxalates. However, Dr. O’Hara says that you definitely DO NOT want to eliminate all foods with oxalates from your diet at once. Going ‘cold turkey’ can cause problems (including kidney stones). Instead, she suggests a gradual reduction over 6-12 months. She also suggests taking epsom salt baths and introducing binders (like magnesium, biotin, and calcium) as supplements to help ferry the oxalates out.  Of course, it is also important to deal with any compounding issues like vitamin deficiencies, mold toxicity, leaky gut or candida.  Every individual treatment plan is going to be different and based on the person.   Mystery Solved In Robin’s case, we found a high level of candida, a B6 deficiency and high oxalate markers through an organic acid test. My suspicions were confirmed. And, it made sense because she was drinking celery juice, putting tons of spinach in her shakes and salads, and eating more nuts in her effort to eat fewer grains. All of which lead to high oxalate intake.  We started by lowering the high oxalate foods in her diet like spinach, sweet potatoes, almond products, and celery juice a little at a time. We added calcium and ...

9 Juli 202047min

The Investigation Chances are you know someone with a gluten sensitivity despite reports that only 6-7% of the population suffer from it. That’s because testing is tricky and false negatives can make people think their health issues are caused by something else. In this episode, I want to break down what’s going on and help you determine if a gluten sensitivity might be at the root of your health mystery.    Understanding Gluten Intolerance Gluten is a protein found in wheat, rye, barley and oats. A person with gluten intolerance cannot digest the protein portion of these grains which triggers an immune response to what the body deems a foreign substance. This immune reaction causes inflammation in the digestive system and damages the lining tissue which, in turn, can cause symptoms like fatigue, bloating, diarrhea, constipation, gas, and cramping. The compromised lining can leave the person more susceptible to bacteria, parasites, and funguses.  Overtime, if a person who has a gluten intolerance continues to eat gluten, their small intestine may also become damaged which leads to malabsorption of nutrients. This can cause fatigue and weight gain. And, the person will be at an increased risk of insomnia, osteoporosis, hormone imbalances, inability to deal with stress, and mood swings. Over time, additional issues may arise like lactose intolerance, depression, leaky gut syndrome (leading to higher susceptibility to infections and other illnesses.) Gluten Intolerance is the Root Cause of Many Health Issues Symptoms of Gluten Intolerance There are many symptoms that could be the result of a gluten intolerance. How many from this list can you check off?    Weight gain Unexplained fatigue Difficulty relaxing, feel tense frequently Unexplained digestive problems Female hormone imbalances, (PMS, menopausal symptoms) Muscle or joint pain or stiffness of unknown cause  Migraine like headaches Food allergies/sensitivities Difficulty digesting dairy products Tendency to over consume alcohol Overly sensitive to physical and emotional pain, cry easily Cravings for sweets, bread, carbohydrates Tendency to overeat sweets, bread, carbohydrates Abdominal pain or cramping Abdominal bloating or distention Intestinal gas “Love” specific foods Eat when upset, eat to relax Constipation or diarrhea of no known cause Unexplained skin problems/rashes Difficulty gaining weight Anorexia Bulimia Rosacea Diabetes Osteoporosis/bone loss Iron deficiency/anemia hronic fatigue Candida Hypoglycemia If you checked off 4 or less it is very unlikely that you have a gluten sensitivity. If you scored between 5 and 8 there may be a reason to suspect it. If you scored 9 or higher there can be a good chance that you are gluten sensitive.   What is a Gluten-Free Diet? Gluten-free means avoiding all foods containing gluten, including wheat, rye, spelt, bulgar, semolina, couscous, kamut and some oats. Gluten can be hidden in processed foods and thickened products such as sauces and soups so read labels carefully. While this can be an adjustment at first, eating gluten free if you are sensitive will make a huge difference in your health.     What’s the Difference between Celiac and Gluten Sensitivity? Celiac disease is an extreme intolerance to gluten where eating gluten will actually damage the lining of your intestines and cause mal-absorption along with many other symptoms such as all types of GI issues, skin issues, headaches, arthritis, depression and the list goes on and on. A gluten sensitivity is when you do not have full-blown celiac and your intestines are not completely damaged but eating gluten makes you feel worse and can often cause very similar if not the same symptoms of those with celiac disease.   What are the Problems with Celiac Testing (and Why is it so Hard to Get a True Answer)? Testing for this is very tricky because the occurrence of false negatives is often likely. The only way to get a true celiac test is to go to the GI doctor and have a biopsy. Your intestines are lined with hair like structures called villi and in healthy intestines; they stand straight up like a shaggy rug. When a person has celiac disease, gluten causes damage to the intestines and the villi lose their integrity and become flattened. The biopsy looks at the state of the villi and only if they are flattened can there be a true celiac diagnosis. Once gluten is removed from their diet, the villi can be revived fairly quickly and thus the intestines will heal.  Patients who already started a gluten free diet prior to their biopsy can often get a false negative because of this. To get a proper diagnosis, the patient should eat gluten (equivalent to at least 1 slice of wheat bread) every day for 30 consecutive days before the biopsy There is also a blood test that can identify the antibodies the body produces against gluten. Some GI doctors use this as a celiac test. The problem here is that the gluten antibodies are produced in significant numbers only if the person has a good functioning immune. With a weak immune system, antibody production will be low and lead to a false negative result. Furthermore, there are several types of antibodies that can be tested such and some of the main ones include IgE, IgG and IgA. IgE shows an immediate response and this often comes out negative unless someone has an anaphylactic shock type reaction to the food which is far less common. IgG and IgA are the delayed antibodies and are more likely to be found through testing because gluten-containing foods take several hours to several days to show symptoms and inflame the immune system.    Testing for Gluten Sensitivity When a celiac test is negative but someone feels worse after consuming gluten (this can happen from 1-72 hours post consumption) they most likely have a sensitivity to gluten. The reason the other tests are negative is because gluten reactions vary in strength. The easiest way to describe this is if you think of a spectrum from 0 to 100 with 0 being no sensitivity and 100 being extremely sensitive. If someone is all the way at 100 it would equate to celiac disease and/or extreme intolerance and often result in a positive biopsy but anything below that would not show up on those tests. So the problem is what if you are at 95? or 85? These cases would show up negative for celiac but as you can see from the example, 95 is still very high on the spectrum and the person would have a pretty severe sensitivity to gluten with all the same symptoms. Testing for sensitivities is also tricky because people can react to gluten through various allergenic pathways and being able to find a possible reactive pathway is the way to see a true result. The major proven pathways include an...

2 Juli 202018min

The Case:  Mindy is 40 but feels like she’s 50.  She often feels achy, tired, struggles to lose weight and thinks she looks older than her age. She didn’t have excessive sun exposure or any genetic history that would explain her premature aging.    The Investigation When I met Mindy, I noticed right away that she was not eating well and so this was my first clue that nutrients and healthy eating were going to be a big part of solving her health mystery but Mindy wanted more. She didn’t just want to stop the premature aging she wanted to reverse it.  Dr. Joseph Antoun is the CEO & Chairman of the Board of L-Nutra which is a nutra-tech company focusing on providing people with knowledge to live to 110 and beyond. I knew he was the best person to discuss Mindy’s case with. He is at the forefront of a push to change our current healthcare system of ‘sick care’ to a more proactive approach.   Healthy-aging and Fasting Scientists have been researching the connection between fasting and aging for decades. Much of this research comes out of the Longevity Institute at the University of  Southern California. What they’ve discovered is that aging happens on a cellular level. When the cells are given fuel (like carbohydrates, proteins, and fats) it accelerates the aging process of the cells. The more we fuel the cells, the faster they age. But, the cells also need fuel to survive. So, the best way to slow the process is to allow the cells to take ‘pit stops’ with intermittent fasting.    How Long Should You Fast? Dr. Antoun shares the benefits of intermittent fasting and prolonged fasting. Using his analogy of pit stops, he explains that these shorter periods of fasting can help slow the aging process of the cells. However, he points out that longer periods of fasting (several days) creates a different cellular reaction. In these longer periods of fasting, the cells become stressed which moves them into a state of autophagy or self-cleaning & self-improving. The discovery of this reaction was so significant, it won the researchers the Nobel  Prize in medicine in 2016.  Prolonged fasting enables major cellular restructuring which contributes to healthy aging. This is because cells can deal with short term fasting by accessing stored fat, protein and carbohydrates. When those stores run out, the cells have to restructure and optimize. Prolonged fasts typically last from 3 - 5 days but these longer fast should be done in a clinic under supervision.    What is the Fasting Mimicking Diet?  Fasting-Mimicking is a system developed by the University of Southern California that allows you to eat specific foods in the right ratios and still be considered fasting, essentially mimicking a fast. This enables people to get all the benefits of fasting without the starvation, losing essential nutrients or needing medical supervision.  The food is specially designed so that the cells don’t recognize it as food.  The diet itself is plant-based, it’s high in good fats (ketoline fats or mid-chain fats) and low in protein and carbs. In the right combination, these nutrients are enough to feed the body and vital organs but just right for your cells to still be able to restructure. Dr. Antoun and his colleagues developed a program that people can follow at home called the ProLon 5-Day Fasting Mimicking Diet Kit and it can’t be simpler. It comes with all the food you need for the 5 days and completely takes any guesswork out because everything is included. This carefully formulated nutrition program nourishes the body with plant-based proteins, fiber rich carbs and healthy fats, and goes undetected by cellular food sensing paths to keep your body in fasting mode. For healthy people interested in supporting their longevity, Dr. Antoun suggests doing a prolonged fast 2-3 times per year.    What is Intermittent Fasting or Intermittent Dieting? This has been the most popular diets for the past two years but Dr. Antoun points out that it’s not really new; it’s how we are supposed to eat. This is the practice of eating our food during a 12-hour period (usually the day) and then not eating for 12-hours (overnight). Dr. Antoun calls this circadian fasting. The body needs a rhythm and our modern lives can interrupt that rhythm. Circadian fasting reinforces that natural rhythm.  The 12-hours of not-eating gives the body time to use the fuel that was gathered in the 12-hours of eating. If the body does not get that time of fasting, it accelerates the use of that fuel which speeds up the aging process.    Is 16-hours of Fasting Too Long?  You might hear people talking about fasting for 16 hours and only eating during an 8-hour window. Dr. Antoun says that this is really only ideal for people with health conditions like obesity, type 2 diabetes, or prediabetic people who need to lose weight quickly. But for those who are not obese or in need of fast weight loss, this is typically not necessary. He also says that the 16 hours is not enough time for the cells to rejuvenate so you are not getting those benefits. Also, the 16:8 is not always sustainable whereas the 12:12 is natural.   Diet and Longevity Aside from intermittent fasting, Dr. Antoun points to research that shows the pescatarian diet is the best for promoting long life. The pescatarian diet is primarily plant-based with protein coming in the form of fish or seafood 2-3 times per week. Other studies have found longevity zones where the diet is more ‘flexitarian’ meaning the diet is primarily plant-based but meat is used for flavoring and not as the primary ingredient in a meal.     Mystery Solved The first step for Mindy was to add more veggies, good fats and antioxidant rich foods into her diet while reducing processed foods and her overall meat intake. She started intermittent fasting for 4 weeks and then did the fasting-mimicking diet. She lost 9 pounds in the first month and her energy skyrocketed. The aches felt better as well.   Next Steps We then did some micronutrient and organic acid testing and saw she was quite deficient in many vitamins and minerals and had too many free radicals. We supported her antioxidant status with Glutathione, Vitamin C and a special annatto form of Vitamin E (more potent than regular vitamin E).  About 8 weeks after we started, she felt significantly better and was ready to do the Prolon 5 Day Fasting Mimicking Diet. The first 2 days were pretty easy. The 3rd day was a bit tougher as she felt a bit hungry. She really started to feel the benefits by the 4th day.    Happy Ending Mindy’s wrinkles didn’t disappear but they felt less deep and her skin was glowing. Overall, she also felt super clear headed and she was down 5 more pounds when she was done. She plans to do another prolonged fast in a few months to maintain her health and vitality.    Eliminating Health Mysteries For Mindy we were able to reset her accelerated aging and help her feel her own age again. Could this be the missing clue for you or someone in your life?    Links: Resources mentioned Than...

25 Juni 202057min

The Case:  Cassandra has been dealing with brain fog and fatigue.  She’s checked her thyroid, takes B-12 & iron and even tried a low-histamine diet More research tied her symptoms to possible mold toxicity and that’s when it clicked.    The Investigation When Cassandra came to me she explained her symptoms and told me that she’d had her home tested for mold (after recalling several large leaks in the past). These tests came back positive. With the mold issue confirmed, it was time to solve her health mysteries and find out if mycotoxins are at play and what damage they’d done.    How Does Mold Threaten Health? Mold can accumulate in the home, office, or schools and it produces mycotoxins that you breath in. Even if your exposure is limited or you can’t see or smell the mold, the mycotoxins can still impact your health. There are 3 main ways it does this:  1. Immune Suppression  Your natural killer cells, T-cells or B-cells become suppressed and fail to fight off infections creating chronic conditions.  2. Decreased Blood Flow to the Brain The frontal lobe is particularly impacted by this decreased blood flow. In fact, brain scans of people with mononeuritis multiplex (decreased blood flow to the brain) and brain scans of people with MS are very similar.  3. Interference with the Nrf2 Pathway  This is the pathway where a lot of detoxification enzymes and antioxidant enzymes are created so when mycotoxins block it, it caused issues with mitochondrial production (for more on mitochondrial issues listen to Episode 22)   Does Mold Always Cause Health Issues? When mold is found in a home, office, or school, it is usually because someone in that environment is experiencing health issues. But, not everyone sharing that space will be affected.  Genetics play a role in how each individual will be affected, but it also has to do with the total allostatic load. The allostatic load has to do with the stress a body is under and how well it is handling that stress. If there are other factors adding to the load (like stress, dysbiosis, chronic infections, blood sugar fluctuations), the exposure to mold can be the tipping point that generates symptoms.  But, even if someone is not symptomatic, it can still be an issue. Individuals may be pre-symptomatic or they may not recognize symptoms. The mold may still be affecting their brain health, energy levels, and organ performance which may not be as noticeable. Everyone is going to experience symptoms in their own way and at different levels.    Symptoms of Mold and Mycotoxins Many people think that mold issues are going to show up like allergies and cause respiratory problems. That can happen but mold can also impact sleep, energy, muscle strength, memory, concentration, and trigger a variety of other symptoms related to the body’s inability to process toxins.    Testing for Mold Toxicity and Mycotoxins People can be exposed to mold in their office or there could be mold in their home. These may not be causing a problem but to be sure, there is a urine test that will measure the mycotoxins in the body. In order to get an accurate assessment of the mycotoxins level, the test should be preceded by a far infrared sauna, use of a BioMat, or taking glutathione to provoke the mycotoxins. Provocation is important because mycotoxins aren’t always visible (even when they’re present) so it’s necessary to ‘stir them up’ a bit. This does not increase the amount, it simply reveals it. If it is not provoked, the test may show low levels and give a false sense of security.    Analyzing Test Results The results of your urine test will reveal the levels of different types of mycotoxins caused by mold. Some of the most common ones are: Gliotoxins  This type of mycotoxin tends to hang out in the brain and the central nervous system. So, the presence of this toxin can be linked to brain issues like, concentration and memory issues (both short and long-term), behavior changes, and in some cases substance abuse disorders. Ochratoxins  This mycotoxin is fairly common (Dr. Jackson sees these the most). It can be carcinogenic and can target the kidneys. Ochratoxin tends to come from aspergillus, which is a mold species that is often odorless and invisible. It might be at home, school, or work but it can also be found in certain foods like nut butters. Aflatoxin M1  This is another mycotoxin caused by aspergillus which tends to impact the respiratory tract. It may also cause liver damage, abdominal pain, coma, gastrointestinal dysfunction and it has also been shown to inhibit certain immune cells called leukocytes.   Verrucarin A and Trichothecenes  These are mycotoxins that come from stachybotrys and fusarium which are very common molds found in buildings with water damage - which is up to 50% of the buildings in America.   You Don’t Have to See Mold or Smell it for it to be Problematic   Testing the Home for Toxic Mold - Locating Mold in the House or Office It can be difficult to identify the source of the mold. There are several ways to test the home or office for mold. Air sample testing is popular but will only show results if there is a very high concentration of mold in the air. More effective testing uses specialized cameras that can look behind the walls. Common breeding grounds for mold include the HVAC system, the bathroom, and the duct work.   Getting Rid of Mold Toxins There are chemical cleaners available for mold abatement but these also have dangerous chemicals. Instead, Dr. Jackson suggests using biodegradable enzymes which act like a molecular PacMan. However, it’s important to look at what caused the mold to make sure it won’t come back. You might want to talk to a healthy home architect or a building biologist.    Treating Elevated Mycotoxin Levels in the Body There are several ways to detoxify and reduce elevated levels of mycotoxins. Binders are commonly used including bio active carbon, PectaSol, Takesumi Supreme (created from bamboo). Sometimes people use a combination. Dr. Jackson suggests taking binders on an empty stomach, away from food, supplements, and medications. It should help excrete the mycotoxins assuming you are moving your bowels twice a day. It is also essential that you avoid further exposure to mold.  Dr. Jackson also suggests a rebounder or dry brushing to stimulate lymphatic drainage. Healthy bile production is also important. Finally, it’s important to make sure there isn’t an limbic loop happening so he recommends the Dynamic Neural Retraining Systems (endorsed by the American Academy of Environmental  Medicine) which reprograms the nervous system.   Mystery Solved Cassandra’s mycotoxin urine test showed that she did in fact have mycotoxins and an organic acid test revealed a decreased mitochondrial function was decreased and elevated levels of free radicals, as well as yeast. This makes total sense as mold is a type of fungus and it can often damage the mitochondria and create free radicals.    Next Steps  Cassandra’s first step was to identify the source of the mold and remediate it from her house through a local expert. To help remove the mycotoxins from her body, she started on

18 Juni 202039min