Talk Python To Me

Talk Python To Me

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

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#532: 2025 Python Year in Review

#532: 2025 Python Year in Review

Python in 2025 is in a delightfully refreshing place: the GIL's days are numbered, packaging is getting sharper tools, and the type checkers are multiplying like gremlins snacking after midnight. On t...

29 Dec 20251h 18min

#531: Talk Python in Production

#531: Talk Python in Production

Have you ever thought about getting your small product into production, but are worried about the cost of the big cloud providers? Or maybe you think your current cloud service is over-architected and...

18 Dec 20251h 21min

#530: anywidget: Jupyter Widgets made easy

#530: anywidget: Jupyter Widgets made easy

For years, building interactive widgets in Python notebooks meant wrestling with toolchains, platform quirks, and a mountain of JavaScript machinery. Most developers took one look and backed away slow...

13 Dec 20251h 11min

#529: Computer Science from Scratch

#529: Computer Science from Scratch

A lot of people building software today never took the traditional CS path. They arrived through curiosity, a job that needed automating, or a late-night itch to make something work. This week, David ...

3 Dec 20251h 17min

#528: Python apps with LLM building blocks

#528: Python apps with LLM building blocks

In this episode, I’m talking with Vincent Warmerdam about treating LLMs as just another API in your Python app, with clear boundaries, small focused endpoints, and good monitoring. We’ll dig into patt...

30 Nov 20251h 16min

#527: MCP Servers for Python Devs

#527: MCP Servers for Python Devs

Today we’re digging into the Model Context Protocol, or MCP. Think LSP for AI: build a small Python service once and your tools and data show up across editors and agents like VS Code, Claude Code, an...

10 Nov 20251h 6min

#526: Building Data Science with Foundation LLM Models

#526: Building Data Science with Foundation LLM Models

Today, we’re talking about building real AI products with foundation models. Not toy demos, not vibes. We’ll get into the boring dashboards that save launches, evals that change your mind, and the shi...

1 Nov 20251h 7min

#525: NiceGUI Goes 3.0

#525: NiceGUI Goes 3.0

Building a UI in Python usually means choosing between "quick and limited" or "powerful and painful." What if you could write modern, component-based web apps in pure Python and still keep full contro...

27 Okt 20251h 17min

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