#481 The Anti-Aging Pill Chinese Scientists Are Developing - Aiming for 120+ Lifespans - Yip Tszho
Siim Land Podcast29 Marras 2025

#481 The Anti-Aging Pill Chinese Scientists Are Developing - Aiming for 120+ Lifespans - Yip Tszho

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Yip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen, China. They're developing pharmaceuticals for extending human lifespan. We discuss their first senolytic called PCC1.

Timestamps:00:00 Intro00:15 Articles about a pill making people live to 15002:50 What is PCC1 and how is it made07:10 How much can targeting senescence extend lifespan12:25 Bon Charge sponsorship13:15 Dose of PCC1 for senolytic and senomorphic effects18:30 PCC1 extending lifespan in mice by 9.4%23:20 Absorption rate of PCC1 and other senolytics27:10 Senolytics for young vs old age31:10 Human study on PCC134:40 What’s the optimal dose for senolytics38:05 Biomarkers of cell senescence40:10 Senolytic benefits on skin and retina46:35 What’s going on in Chinese longevity science52:10 Future direction of PCC1PCC1 studies: https://lonvibio.com/pages/science

Jaksot(512)

#480 The Science of Saunas: How Heat Boosts Fitness & Longevity - Brady Holmer MSc

#480 The Science of Saunas: How Heat Boosts Fitness & Longevity - Brady Holmer MSc

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandBrady Holmer is a science writer and researcher with a Master's degree in Human Performance from the ...

21 Marras 202559min

#479 Longevity Testing 101: What Really Matters (with Siim Land and Dr. Joy Kong)

#479 Longevity Testing 101: What Really Matters (with Siim Land and Dr. Joy Kong)

Join our upcoming retreat in January 2026: https://www.siimland.co/retreat Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:4...

14 Marras 20251h 4min

#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky

#478 Mitochondria Scientist: The Only Proven Way to Extend Human Lifespan - Dr Mark Tarnopolsky

Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metab...

8 Marras 202559min

#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner

#477 The Science of Longevity Genes: What We’ve Learned from Centenarians - Dr Tyler Panzner

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longev...

31 Loka 20251h

#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast

#476 Siim Land on Human Immortality, Gene Editing, Biomarkers - The Beyond Tomorrow Podcast

Timestamps0:00 – Introduction4:12 – Humans adapt, and that changes the rules9:58 – Diet diversity, sensitivities, and n of 116:51 – Assess first: biomarkers that predict disease risk18:27 – Fixing sle...

24 Loka 20251h 6min

#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more

#475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimlandTimestamps:00:00 Does exercise increase inflammation03:03 Melatonin megadosing research04:23 NOVOS vs...

18 Loka 202547min

#474 Longevity Supplements Ranked From Best to Worst

#474 Longevity Supplements Ranked From Best to Worst

Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025Timestamps:00:00 Intro00:14 Taurine01:19 Apigenin01:55 Resveratrol03:20 Rapamycin04:55 Metformin06:11 Calcium AKG07:30 Melaton...

10 Loka 202537min

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