The association between radioresistance and tumour evolution

The association between radioresistance and tumour evolution

Is a tumour's ability to evolve and adapt over time linked to why it becomes resistant to radiotherapy? And if so, what can we do to overcome this radioresistance? In this episode, Dr Christopher Jones and Dr Ashley Nicholls from CRUK RadNet Cambridge at the University of Cambridge explore these questions. They explain why some tumours are resistant to radiation and why some patients are more resistant to treatment than others. They also offer insights into why recurrence happens and how to identify it early in order to treat it more effectively with new technologies. This includes designing new tools to make drug delivery more accurate and new genetic approaches to investigate specific ways to treat cancer in the context of radiation. Chris works predominantly in oesophageal cancer, while Ash studies lung cancer, but both strive to understand why relapse and radioresistance occur to then try to target these cancers with specific drugs or drug combinations to lessen toxicity and help personalise treatment.

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Jaksot(67)

Why patient and public involvement and engagement is important and what it means to those involved

Why patient and public involvement and engagement is important and what it means to those involved

Have you ever thought about getting involved in research as a patient or supporter? In this episode, Ellie Wolmark talks to the incredible members of the Women⁺s Cancers Programme Patient and Public ...

12 Marras 20251h 16min

Using AI to mathematically model the progression of glioblastoma

Using AI to mathematically model the progression of glioblastoma

Can we use artificial intelligence (AI) to predict where a brain tumour might recur at the point of first diagnosis in order to pre-emptively treat it to stop recurrence? Dr Francesca Cozzi (a PhD s...

8 Loka 202528min

Studying the tumour microenvironment

Studying the tumour microenvironment

Could the environment around a cancer tumour hold the key to better treatments? In this episode, PhD students Emily Lythgoe and Ellie Bunce from the University of Cambridge discuss their research int...

24 Syys 202532min

Building a tissue time machine

Building a tissue time machine

What if a time machine could be built, not from metal but from human tissue, to help us understand cancer and how it responds to treatment? Dr Alecia-Jane Twigger, Dr Akanksha Anand, Dr Kui Hua, Dr P...

10 Syys 202545min

Using AI in the screening and treatment of kidney cancer

Using AI in the screening and treatment of kidney cancer

Have you ever wondered how artificial intelligence (AI) is used in research in a healthcare setting? Rebecca Wray and Bill McGough, two PhD students at the University of Cambridge, both use AI in diff...

27 Elo 202533min

Using AI to detect stomach cancer during endoscopy

Using AI to detect stomach cancer during endoscopy

How can artificial intelligence (AI) support both cancer research and healthcare more generally? Anoushka Harit (University of Cambridge) and Dr Zhongtian Sun (University of Kent) join today's episode...

13 Elo 202547min

Ask me anything about... cachexia research and management

Ask me anything about... cachexia research and management

What do you most want to know about pancreatic cancer and cancer-associated cachexia? In this special episode, we bring you a recording of a live 'Ask Me Anything (AMA)' event hosted by the CRUK Camb...

30 Heinä 202544min

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