Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry
RealTalk MS2 Maalis

Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry

You know them by their trade names such as Ozempic, Wegovy, Mounjaro, and Zepbound. This class of medications is known as GLP-1 receptor agonists. And while they are best known for managing diabetes and promoting weight loss, researchers are finding that these drugs are also effective in a broad range of other health conditions. So, what about MS?

My guest this week is Dr. Ellen Mowry, the principal investigator of a clinical trial to determine whether a GLP-1 drug can reduce brain inflammation and provide neuroprotection in people living with progressive MS.

We're sharing details about the discovery of a new biomarker that not only confirms an MS diagnosis but also predicts the severity of an individual's disease course in the years ahead.

We'll tell you about three studies focused on better managing some of the most common MS symptoms and funded by the International Progressive MS Alliance.

And we'll explain how Merck and the Mayo Clinic are partnering to build a first-of-its-kind drug discovery platform using AI.

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: A GLP-1 for MS? :22

I'm asking for your support: 1:31

Researchers discover biomarkers that can predict future disease course 2:13

The International Progressive MS Alliance invests $8.1 million in global studies that address the most common MS symptoms 5:44

Merck and the Mayo Clinic collaborate on AI-driven drug discovery platform 10:02

Dr. Ellen Mowry discusses the clinical trial to determine whether a GLP-1 drug can reduce inflammation in the central nervous system and offer neuroprotection to people with progressive MS 12:20

Share this episode 30:17

Next week 30:38

SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/444

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!

LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Support Jon at WALK MS
https://realtalkms.com/walkms

STUDY: Large-Scale Proteomics Across Neurological Disorders Uncovers Biomarker Panel and Targets in Multiple Sclerosis
https://pubmed.ncbi.nlm.nih.gov/41747728

International Progressive MS Alliance
https://progressivemsalliance.org

JOIN: The RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

REVIEW: Give RealTalk MS a rating and review
http://www.realtalkms.com/review

Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 444
Guests: Dr. Ellen Mowry

Privacy Policy

Jaksot(502)

Episode 440: An MS Specialist's Response to the FDA with Dr. William Conte

Episode 440: An MS Specialist's Response to the FDA with Dr. William Conte

This past December, the FDA issued a Complete Response Letter to drug manufacturer Sanofi in response to Sanofi's application seeking approval for Tolebrutinib, the first in a new category of investig...

2 Helmi 39min

Episode 439: Preventing MS with Dr. Bruce Bebo

Episode 439: Preventing MS with Dr. Bruce Bebo

The first coordinated global research strategy to prevent MS has been announced. This week, Dr. Bruce Bebo, the National MS Society's Executive Vice President and Chief Research & Medical Affairs Offi...

26 Tammi 32min

Episode 438: The Discovery of 2 MS Subtypes with Dr. Arman Eshaghi

Episode 438: The Discovery of 2 MS Subtypes with Dr. Arman Eshaghi

One of the more confusing aspects of MS is that it can present differently from one person to the next. A research team at University College London may have uncovered a reason for that when they iden...

19 Tammi 29min

Episode 437: Remembering David Mitchell

Episode 437: Remembering David Mitchell

I don't have to remind anyone who listens to this podcast that the cost of MS disease-modifying therapies is obscenely high. And we're not just talking about relatively new medications. Older medicati...

12 Tammi 29min

Episode 436: 3 Questions Your Neurologist Should Be Asking Themselves with Dr. Leorah Freeman

Episode 436: 3 Questions Your Neurologist Should Be Asking Themselves with Dr. Leorah Freeman

Scientists are expanding our understanding of MS at an unprecedented pace. This week, Dr. Leorah Freeman discusses why, as new discoveries and medications enter clinical practice, neurologists and MS ...

5 Tammi 34min

Episode 435: Revisiting ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug

Episode 435: Revisiting ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug

We're closing out the year by revisiting the most listened-to episode of RealTalk MS in 2025. And it shouldn't come as a major surprise that this year's most listened-to episode was our review of the ...

29 Joulu 202524min

Episode 434: Revisiting Managing Menopause While You're Managing MS with Dr. Riley Bove

Episode 434: Revisiting Managing Menopause While You're Managing MS with Dr. Riley Bove

The holiday season gives me the opportunity to indulge in what's become a RealTalk MS tradition. I reserve the last two episodes in December to revisit the most popular conversations that I've had ove...

22 Joulu 202521min

Episode 433: Our Most Important Conversations of 2025 with Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, and Dr. Stehen Krieger

Episode 433: Our Most Important Conversations of 2025 with Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, and Dr. Stehen Krieger

As the year draws to a close, we wanted to share some of the most compelling conversations we've had over the past 12 months. And rather than make my own picks, we went through the hundreds of emails ...

15 Joulu 202543min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
tiedenaiset-podcast
rss-pitaisko-erota
vakeva-elama-viisaampi-mieli-vahvempi-keho
rss-narsisti
meditaatiot-suomeksi
terapiassa
junnut-pelissa
puhu-muru
aamukahvilla
rss-kuumilla-aalloilla
paritellen
rss-uplevel-by-sonja-hannus
rss-nautinto
rss-pt-paahtio
rss-mighty-finland-podcast
paaasia-podcast
katilon-kahvitunti