#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana

#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana

Today, I'm joined by the extraordinary Dr. Natalie Yivgi-Ohana, a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age. Episode Timestamps: Welcome to the Longevity Podcast and today's focus on mitochondria ... 00:00:00 Maternal inheritance and critical functions of mitochondria ... 00:05:56 Mitochondria as energy producers and hormone regulators ... 00:07:03 Aha moments: mitochondria control life, death, and disease ... 00:08:55 Endosymbiotic theory: how mitochondria originated ... 00:10:19 Chronic disease, aging, and the connection to mitochondria ... 00:16:10 Substrate fuels: carbs, fats, and importance of metabolic flexibility ... 00:20:18 Mitochondria's control over immune system and signaling ... 00:26:39 Mitochondrial transfer: how cells share organelle "powerhouses" ... 00:32:42 Groundbreaking therapy: transplanting mitochondria for rare diseases ... 00:36:40 Expanding mitochondrial therapies to age-related diseases ... 00:42:57 Aging in women: hormones, mitochondria, and inflection points ... 00:51:00 Stem cell exhaustion and cellular renewal ... 00:52:24 Biomarkers: ways to measure mitochondrial health ... 01:03:11 Supplements, lifestyle, and emotional health for mitochondria ... 01:15:47 Medication choices and minimizing mitochondrial toxicity ... 01:24:04 Our Amazing Sponsors: O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off. Magnesium Breakthrough by BIOptimizers — A full-spectrum magnesium supplement combining seven highly absorbable forms to support sleep, stress, muscle recovery, and nervous system balance in one nightly habit. Save 15% at bioptimizers.com/bionat with code BIONAT Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

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#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why "Healthy Sedentary" Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

#407: How MUSCLE Changes Everything: The Secret Organ of Longevity | Why "Healthy Sedentary" Is a Myth (and What To Do Instead) With Dr. Gabrielle Lyon

Today, I'm joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriat...

27 Tammi 1h 15min

#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete d...

23 Tammi 1h 27min

#405: Heart Attacks Aren't What You Think | The Plaque LIE That Changes Everything (Cardiology 2.0) With Dr. Sanjay Bhojraj

#405: Heart Attacks Aren't What You Think | The Plaque LIE That Changes Everything (Cardiology 2.0) With Dr. Sanjay Bhojraj

Today, I'm joined by the deeply thoughtful and refreshingly honest Dr. Sanjay Bhojraj, a self-described "curious cardiologist" who spent decades treating heart attacks in the cath lab — before steppin...

20 Tammi 1h 31min

#404: The Dirty Truth About Your Home's WATER (And Why Most Filters Including Reverse Osmosis Don't Cut It) With Charles Bohdy and Victor Sagalovsky

#404: The Dirty Truth About Your Home's WATER (And Why Most Filters Including Reverse Osmosis Don't Cut It) With Charles Bohdy and Victor Sagalovsky

Today, I'm joined by Charles Bohdy, a true innovator in water purification technology, and Victor Sagalovsky, a passionate advocate for bringing the science of water quality into our daily lives. Toge...

16 Tammi 1h 25min

#403: What's REALLY In Your Food? | Dark Secrets of Ultra-Pasteurized Milk, Natural Flavors & Microplastics EXPOSED With Ben Katz

#403: What's REALLY In Your Food? | Dark Secrets of Ultra-Pasteurized Milk, Natural Flavors & Microplastics EXPOSED With Ben Katz

Today, I'm joined by Ben Katz—better known online as Mr. Mass Spec —an academic analytical chemist from UC Irvine whose mission is to uncover what's really in our everyday foods, drinks, and products....

13 Tammi 1h 17min

#402: Gut Reset: The SECRET Signals for Longevity Revealed | How to Heal Your Microbiome, Banish Bloating, and Build Resilience With Nat Niddam

#402: Gut Reset: The SECRET Signals for Longevity Revealed | How to Heal Your Microbiome, Banish Bloating, and Build Resilience With Nat Niddam

Today, I'm kicking off the new year with a back-to-basics deep dive into one of the most pivotal yet overlooked foundations of longevity: gut health. Over the past episodes, we've explored everything ...

9 Tammi 1h 2min

#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff

#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff

Today, I'm joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley ...

6 Tammi 1h 38min

#400: Why Chasing Muscle for Longevity Might Backfire: The Real Keys to Aging Well With Joel Greene.

#400: Why Chasing Muscle for Longevity Might Backfire: The Real Keys to Aging Well With Joel Greene.

Today, I'm excited to bring back the always thought-provoking Joel Greene, author of "The Immunity Code" and "The Way," for a fresh conversation on why true longevity is about so much more than how mu...

2 Tammi 1h 33min

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