#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

Today, I'm joined by the inspiring Leslie Kenny, Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path—reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable.

Leslie has a generous offer for you, when you visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout you'll get 20% off.

Episode Timestamps:

Welcome, show intro, and overview ... 00:00:00

Leslie Kenny's health journey and reversing disease ... 00:00:30

Biological vs. chronological age and the immune system ... 00:04:55

Impact of trauma and stress on aging ... 00:11:51

Overcoming prognosis: lifestyle and scientific interventions ... 00:18:02

Diet, tracking, and removing triggers ... 00:22:21

The overlooked importance of thyroid health ... 00:32:23

Dangers of overdoing fasting and hormesis ... 00:40:21

Autophagy basics and the cellular cleanup crew ... 00:44:06

Spermidine's role, sourcing, and supplement quality ... 01:10:19

Optimizing longevity habits and daily routines ... 01:29:44

Our Amazing Sponsors:

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BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.


Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to http://www.profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order.

Nat's Links:

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