#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

Today, I'm joined by the inspiring Leslie Kenny, Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path—reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable. Leslie has a generous offer for you, when you visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout you'll get 20% off. Episode Timestamps: Welcome, show intro, and overview ... 00:00:00 Leslie Kenny's health journey and reversing disease ... 00:00:30 Biological vs. chronological age and the immune system ... 00:04:55 Impact of trauma and stress on aging ... 00:11:51 Overcoming prognosis: lifestyle and scientific interventions ... 00:18:02 Diet, tracking, and removing triggers ... 00:22:21 The overlooked importance of thyroid health ... 00:32:23 Dangers of overdoing fasting and hormesis ... 00:40:21 Autophagy basics and the cellular cleanup crew ... 00:44:06 Spermidine's role, sourcing, and supplement quality ... 01:10:19 Optimizing longevity habits and daily routines ... 01:29:44 Our Amazing Sponsors: Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20. Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to http://www.profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

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#399: Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam

#399: Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam

Today, I'm joined by a lineup of trailblazers in the science of longevity: Ben Azadi, Dr. Teo Soleymani, Dr. Carrie Jones, Ian White, Dr. Robert Lufkin, and Dr. Jenn Simmons . Together we dig into som...

26 Joulu 202538min

#398: The Dopamine Biohack | Brain Chemistry, Motivation & Testosterone Secrets Revealed With Lucas Aoun

#398: The Dopamine Biohack | Brain Chemistry, Motivation & Testosterone Secrets Revealed With Lucas Aoun

Today, I'm joined by Lucas Aoun, from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father's ...

23 Joulu 20251h 24min

#397: STRESS: The Silent Accelerator of Aging (10 Free Hacks Rewiring Your Longevity) | Calm Amid Chaos With Nat Niddam

#397: STRESS: The Silent Accelerator of Aging (10 Free Hacks Rewiring Your Longevity) | Calm Amid Chaos With Nat Niddam

Today, it's just me, and we're doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives...

19 Joulu 202539min

#396: From Trauma to Transcendence: Alpha Training, Elite Creativity Gains, and Reversing Aging — With Dr. James Hardt

#396: From Trauma to Transcendence: Alpha Training, Elite Creativity Gains, and Reversing Aging — With Dr. James Hardt

Today, I'm joined by Dr. James Hardt—founder of Biocybernaut and a true pioneer in the world of neurofeedback. With over four decades spent mapping how our brainwaves shape emotions, performance, and ...

16 Joulu 20251h 23min

#395: Brain Fog, Anger, Detox Secrets & The Truth About Diet Sodas | Unlocking LIVER Longevity With Siggi Clavien

#395: Brain Fog, Anger, Detox Secrets & The Truth About Diet Sodas | Unlocking LIVER Longevity With Siggi Clavien

Today, I'm sitting down with the irrepressible Siggi Clavien, renowned biotech innovator and founder of De-liver-ance, a groundbreaking formula for liver health. Siggi's story is deeply personal—motiv...

12 Joulu 20251h 33min

#394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence

#394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence

Today, I'm joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly ...

9 Joulu 20251h 43min

#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso

#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso

Today, I'm joined by the incomparable Dr. Ted Achacoso—a true pioneer in shifting healthcare from "what's wrong with you" to "what's right with you." Trained across neurology, pharmacology, AI, and nu...

5 Joulu 20251h 37min

#392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud's Jon Hacker Unlocks REST

#392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud's Jon Hacker Unlocks REST

Today, I'm joined by the innovative Jon Hacker, whose name couldn't be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mi...

2 Joulu 20251h 4min

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