2837: The Methylene Blue Masterclass: Cutting-Edge Mitochondrial Support with Dr. Scott Sherr

2837: The Methylene Blue Masterclass: Cutting-Edge Mitochondrial Support with Dr. Scott Sherr

This is one of the BEST interviews we've ever done on supplements and cutting-edge supplement technology... We had Dr. Scott Sherr on the podcast — a board-certified internal medicine physician who practices health optimization medicine and hyperbaric oxygen therapy. This guy KNOWS his stuff and we break down some of the most powerful compounds you can get your hands on to improve cognitive function, athletic performance, and longevity.

Here's the reality... 94% of US adults are metabolically UNHEALTHY. That means your mitochondria — the powerhouses of your cells — are struggling to produce the energy you need. Dr. Sherr explains exactly why this happens, how it connects to everything from anxiety and depression to fat loss struggles, and what you can actually DO about it. We dive DEEP into methylene blue — the first drug ever registered with the FDA back in 1897 — and why it's become one of the most powerful tools for supporting mitochondrial function and energy production.

But it doesn't stop there... We cover the GABAergic system and why most people are walking around GABA deficient (hello anxiety, insomnia, and mood issues), the synergy between methylene blue and red light therapy, how to use these compounds for travel, and a complete sleep optimization stack that could finally get you those 90+ Oura Ring scores. If you're tired of being tired, stressed about being stressed, or just want to understand how to actually support your body at a cellular level — this episode is a MUST listen.

MAPS PPL — https://mapsppl.com (code: ppl)

SPONSORS
Troscriptions — https://troscriptions.com/mindpump (code: mindpump)
Seed — https://seed.com/mindpump (code: 25mindpump)

00:00 — Intro
5:56 — Dr. Scott Sherr's background and health optimization medicine framework
10:42 — Strengths and weaknesses of conventional vs alternative medicine
16:34 — Why 94% of US adults are metabolically unhealthy
22:30 — The 'sympathetic spiral of doom' and why doing MORE isn't better
25:48 — Deep dive into methylene blue — history and mechanisms
35:09 — MAO inhibition, serotonin syndrome risk, and dosing protocols
42:43 — Methylene blue and red light therapy synergy
48:55 — GABA system, B3-GABA, and the TroCalm formula explained
59:58 — Complete sleep optimization stack and nighttime routine
67:30 — Cordycepin benefits and immune support protocols

PEOPLE MENTIONED
Dr. Scott Sherr — Guest — board-certified internal medicine physician, health optimization medicine practitioner, co-founder of Troscriptions
Dr. Ted Achacoso — Founder of Troscriptions and the Health Optimization Medicine nonprofit, mentor to Dr. Sherr
Alan Sherr — Dr. Sherr's father — chiropractor for 45+ years who influenced his alternative medicine philosophy
Francisco Gonzalez Lima — Researcher at University of Texas Austin studying methylene blue for Alzheimer's, TBI, and stroke
Thomas DeLauer — Mutual friend who uses methylene blue 2-3 times per week on high-stress days
Paul Stamets — Referenced regarding mushroom knowledge and Amanita Muscaria/Santa Claus connection

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2904: How to Reverse Osteoporosis and Osteopenia (The Data-Backed Formula That Actually Works)

2904: How to Reverse Osteoporosis and Osteopenia (The Data-Backed Formula That Actually Works)

In this episode the guys break down how to reverse osteopenia and osteoporosis — explaining the difference between the two, why 43% of adults over 50 have low bone mass, and why this is actually very ...

18 Heinä 1h 54min

2903:  How to Build Bulletproof Joints (So You Can Train for the Rest of Your Life)

2903: How to Build Bulletproof Joints (So You Can Train for the Rest of Your Life)

In this episode the guys break down six ways to build bulletproof joints — proper strength training, unilateral training, static stretching post-workout, mobility drills, hydration with high protein d...

17 Heinä 1h 8min

2902: How 311 Has Stayed Together for 35 Years — Nick Hexum on Sobriety, Fitness and Creativity

2902: How 311 Has Stayed Together for 35 Years — Nick Hexum on Sobriety, Fitness and Creativity

In this episode the guys sit down with Nick Hexum, lead singer and co-founder of 311, just hours before a live show. Nick opens up about how the band has stayed together for 35 years, his path to sobr...

16 Heinä 1h 7min

2901: Chronic Pain Causes | 5 Common Habits That Make Pain Worse

2901: Chronic Pain Causes | 5 Common Habits That Make Pain Worse

In this episode the guys break down five weird and common things people do that cause or worsen chronic pain — poor sleep, inflammatory diet, macro and micro deficiencies, dehydration, and shallow bre...

15 Heinä 2h 2min

2900: 6 Mistakes Women Make When They Start Lifting

2900: 6 Mistakes Women Make When They Start Lifting

You're putting in the work at the gym, eating what you think is enough, and still not seeing the body you're training for. Sound familiar? In this episode of Mind Pump Show, Sal, Adam, and Justin brea...

13 Heinä 26min

2899: How to Lose 15 Pounds in 90 Days | The 5-Step Fat Loss Formula

2899: How to Lose 15 Pounds in 90 Days | The 5-Step Fat Loss Formula

In this episode the guys break down the exact five-step formula to lose 15 pounds of pure body fat in 90 days — lifting 1-2 compound movements daily, walking after every meal, eating only whole foods,...

11 Heinä 1h 39min

2898: How to Do Pull Ups in 30 Days (The Exact Method That Actually Works)

2898: How to Do Pull Ups in 30 Days (The Exact Method That Actually Works)

In this episode the guys break down exactly how to be able to do pull ups in 30 days — covering the daily low intensity practice method, why you need to drop all other back work, why eating more and s...

10 Heinä 1h 15min

2897: How to Build Glutes, Quads, and Shoulders (The Body Women Actually Want)

2897: How to Build Glutes, Quads, and Shoulders (The Body Women Actually Want)

In this episode the guys break down exactly how to build the glutes, quads, and shoulders that women actually want — covering why you should train your priority body part first in the workout, how to ...

9 Heinä 25min

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