234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Jaksot(415)

278 | Kieran Healy on the Technology of Ranking People

278 | Kieran Healy on the Technology of Ranking People

We claim to love all of our children, friends, and students equally. But perhaps deep down you assign a ranking to them, from favorite to not-so-favorite. Ranking and quantifying people is an irresist...

10 Kesä 20241h 15min

AMA | June 2024

AMA | June 2024

Welcome to the June 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

3 Kesä 20243h 58min

277 | Cumrun Vafa on the Universe According to String Theory

277 | Cumrun Vafa on the Universe According to String Theory

String theory, the current leading candidate for a theory of quantum gravity as well as other particles and forces, doesn't connect directly to the world we see. It's possible that there is a large la...

27 Touko 20241h 22min

276 | Gavin Schmidt on Measuring, Predicting, and Protecting Our Climate

276 | Gavin Schmidt on Measuring, Predicting, and Protecting Our Climate

The Earth's climate keeps changing, largely due to the effects of human activity, and we haven't been doing enough to slow things down. Indeed, over the past year, global temperatures have been higher...

20 Touko 20241h 19min

275 | Solo: Quantum Fields, Particles, Forces, and Symmetries

275 | Solo: Quantum Fields, Particles, Forces, and Symmetries

Publication week! Say hello to Quanta and Fields, the second volume of the planned three-volume series The Biggest Ideas in the Universe. This volume covers quantum physics generally, but focuses espe...

13 Touko 20242h 12min

AMA | May 2024

AMA | May 2024

Welcome to the May 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreon...

6 Touko 20243h 35min

274 | Gizem Gumuskaya on Building Robots from Human Cells

274 | Gizem Gumuskaya on Building Robots from Human Cells

Modern biology is advancing by leaps and bounds, not only in understanding how organisms work, but in learning how to modify them in interesting ways. One exciting frontier is the study of tiny "robot...

29 Huhti 20241h 10min

273 | Stefanos Geroulanos on the Invention of Prehistory

273 | Stefanos Geroulanos on the Invention of Prehistory

Humanity itself might be the hardest thing for scientists to study fairly and accurately. Not only do we come to the subject with certain inevitable preconceptions, but it's hard to resist the temptat...

22 Huhti 20241h 19min

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