234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Jaksot(416)

273 | Stefanos Geroulanos on the Invention of Prehistory

273 | Stefanos Geroulanos on the Invention of Prehistory

Humanity itself might be the hardest thing for scientists to study fairly and accurately. Not only do we come to the subject with certain inevitable preconceptions, but it's hard to resist the temptat...

22 Huhti 20241h 19min

272 | Leslie Valiant on Learning and Educability in Computers and People

272 | Leslie Valiant on Learning and Educability in Computers and People

Science is enabled by the fact that the natural world exhibits predictability and regularity, at least to some extent. Scientists collect data about what happens in the world, then try to suggest "law...

15 Huhti 20241h 8min

AMA | April 2024

AMA | April 2024

Welcome to the April 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patre...

8 Huhti 20243h 14min

271 | Claudia de Rham on Modifying General Relativity

271 | Claudia de Rham on Modifying General Relativity

Einstein's theory of general relativity has been our best understanding of gravity for over a century, withstanding a variety of experimental challenges of ever-increasing precision. But we have to be...

1 Huhti 20241h 21min

270 | Solo: The Coming Transition in How Humanity Lives

270 | Solo: The Coming Transition in How Humanity Lives

Technology is changing the world, in good and bad ways. Artificial intelligence, internet connectivity, biological engineering, and climate change are dramatically altering the parameters of human lif...

25 Maalis 20242h 9min

269 | Sahar Heydari Fard on Complexity, Justice, and Social Dynamics

269 | Sahar Heydari Fard on Complexity, Justice, and Social Dynamics

When it comes to social change, two questions immediately present themselves: What kind of change do we want to see happen? And, how do we bring it about? These questions are distinct but related; the...

18 Maalis 20241h 11min

AMA | March 2024

AMA | March 2024

Welcome to the March 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patre...

11 Maalis 20243h 55min

268 | Matt Strassler on Relativity, Fields, and the Language of Reality

268 | Matt Strassler on Relativity, Fields, and the Language of Reality

In the 1860s, James Clerk Maxwell argued that light was a wave of electric and magnetic fields. But it took over four decades for physicists to put together the theory of special relativity, which cor...

4 Maalis 20241h 30min

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