234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Jaksot(415)

45 | Leonard Susskind on Quantum Information, Quantum Gravity, and Holography

45 | Leonard Susskind on Quantum Information, Quantum Gravity, and Holography

For decades now physicists have been struggling to reconcile two great ideas from a century ago: general relativity and quantum mechanics. We don't yet know the final answer, but the journey has taken...

6 Touko 20191h 13min

44 | Antonio Damasio on Feelings, Thoughts, and the Evolution of Humanity

44 | Antonio Damasio on Feelings, Thoughts, and the Evolution of Humanity

When we talk about the mind, we are constantly talking about consciousness and cognition. Antonio Damasio wants us to talk about our feelings. But it's not in an effort to be more touchy-feely; Damasi...

29 Huhti 20191h 12min

43 | Matthew Luczy on the Pleasures of Wine

43 | Matthew Luczy on the Pleasures of Wine

Some people never drink wine; for others, it's an indispensable part of an enjoyable meal. Whatever your personal feelings might be, wine seems to exhibit a degree of complexity and nuance that can be...

22 Huhti 20191h 46min

42 | Natalya Bailey on Navigating Earth Orbit and Beyond

42 | Natalya Bailey on Navigating Earth Orbit and Beyond

The space age officially began in 1957 with the launch of the Sputnik 1 satellite. But recent years have seen the beginning of a boom in the number of objects orbiting Earth, as satellite tracking and...

15 Huhti 201959min

41 | Steven Strogatz on Synchronization, Networks, and the Emergence of Complex Behavior

41 | Steven Strogatz on Synchronization, Networks, and the Emergence of Complex Behavior

One of the most important insights in the history of science is the fact that complex behavior can arise from the undirected movements of small, simple systems. Despite the fact that we know this, we'...

8 Huhti 20191h 14min

40 | Adrienne Mayor on Gods and Robots in Ancient Mythology

40 | Adrienne Mayor on Gods and Robots in Ancient Mythology

The modern world is full of technology, and also with anxiety about technology. We worry about robot uprisings and artificial intelligence taking over, and we contemplate what it would mean for a comp...

1 Huhti 20191h 3min

39 | Malcolm MacIver on Sensing, Consciousness, and Imagination

39 | Malcolm MacIver on Sensing, Consciousness, and Imagination

Consciousness has many aspects, from experience to wakefulness to self-awareness. One aspect is imagination: our minds can conjure up multiple hypothetical futures to help us decide which choices we s...

25 Maalis 20191h 19min

38 | Alan Lightman on Transcendence, Science, and a Naturalist's Sense of Meaning

38 | Alan Lightman on Transcendence, Science, and a Naturalist's Sense of Meaning

Let's say, for sake of argument, that you don't believe in God or the supernatural. Is there still a place for talking about transcendence, the sacred, and meaning in life? Some of the above, but not ...

18 Maalis 20191h 16min

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