234 | Tobias Warnecke on Cellular Structure and Evolution

234 | Tobias Warnecke on Cellular Structure and Evolution

Eukaryotic cells manage to pull off a number of remarkable feats. One is packing quite a long DNA molecule, with potentially billions of base pairs, into a tiny central nucleus. A key role is played by histones, proteins that provide scaffolding for DNA to wrap around. Histones also appear in archaea (one of the other domains of life), but until recently there wasn't evidence for them in bacteria (the final of the three domains). Todays guest, Tobias Warnecke, is an author on a recent paper that claims to provide such evidence. We discuss this new result, as well as background questions of how cells evolved and what their current structure can teach us about their histories.

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Tobias Warnecke received his Ph.D. in biology from the University of Bath. He is currently a Programme Leader and MRC Investigator at the London Institute of Medical Sciences. He is a co-author on A. Hochner et al. (2023), "Histone-Organized Chromatin in Bacteria."


Jaksot(415)

37 | Edward Watts on the End of the Roman Republic and Lessons for Democracy

37 | Edward Watts on the End of the Roman Republic and Lessons for Democracy

When many of us think "Ancient Rome," we think of the Empire and the Caesars. But the Empire was preceded by the Roman Republic, which flourished for a full five centuries. Why, after such a long and ...

11 Maalis 20191h 31min

36 | David Albert on Quantum Measurement and the Problems with Many-Worlds

36 | David Albert on Quantum Measurement and the Problems with Many-Worlds

Quantum mechanics is our best theory of how reality works at a fundamental level, yet physicists still can't agree on what the theory actually says. At the heart of the puzzle is the "measurement prob...

4 Maalis 20191h 42min

35 | Jessica Yellin on The Changing Ways We Get Our News

35 | Jessica Yellin on The Changing Ways We Get Our News

Everything we think about the world outside our immediate senses is shaped by information brought to us by other sources. In the case of what's currently happening to the human race, we call that info...

25 Helmi 20191h 8min

34 | Paul Bloom on Empathy, Rationality, Morality, and Cruelty

34 | Paul Bloom on Empathy, Rationality, Morality, and Cruelty

Within every person's mind there is on ongoing battle between reason and emotion. It's not always a battle, of course; very often the two can work together. But at other times, our emotions push us to...

18 Helmi 20191h 10min

33 | James Ladyman on Reality, Metaphysics, and Complexity

33 | James Ladyman on Reality, Metaphysics, and Complexity

Reality is a tricky thing. Is love real? What about the number 5? This is clearly a job for a philosopher, and James Ladyman is one of the world's acknowledged experts. He and his collaborators have b...

11 Helmi 20191h 7min

32 | Naomi Oreskes on Climate Change and the Distortion of Scientific Facts

32 | Naomi Oreskes on Climate Change and the Distortion of Scientific Facts

Our climate is in the midst of dramatic changes, driven largely by human activity, with potentially enormous consequences for humanity and other species. That's why science tells us, anyway. But there...

4 Helmi 20191h 10min

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

31 | Brian Greene on the Multiverse, Inflation, and the String Theory Landscape

String theory was originally proposed as a relatively modest attempt to explain some features of strongly-interacting particles, but before too long developed into an ambitious attempt to unite all th...

28 Tammi 20191h 11min

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

30 | Derek Leben on Ethics for Robots and Artificial Intelligences

It's hardly news that computers are exerting ever more influence over our lives. And we're beginning to see the first glimmers of some kind of artificial intelligence: computer programs have become mu...

21 Tammi 20191h 28min

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