#456: The Bioregulator Debate: What Actually Works (And What Doesn't) With Dr. Marios Kyriazis

📍 Please don’t forget to follow my NEW Instagram account at https://www.instagram.com/longevitywithnat/ For years we've talked about longevity as if the answer is hiding in the next supplement, biomarker, or miracle molecule. But what if we've been looking at aging through far too narrow a lens? Today's guest, Dr. Marios Kyriazis, has spent decades challenging that idea by exploring aging through medicine, complexity science, cybernetics, and even philosophy. We unpack what bioregulators actually are, why so much of the conversation around them has become overhyped, and how concepts like hormesis, adaptation, and even our relationship with technology may shape how we age. This is one of those conversations that starts with peptides and ends with a much bigger question: what does it really mean to build a longer, healthier life? Where to find Bioregulators: visit https://profound-health.com/?Aff=Longevity15 and use code NAT15 for 15% off your first order Episode Timestamps: Introduction to Dr. Marios Kyriazis & Rethinking Aging ... 00:00:00 Why Humans Age Differently Than Animals ... 00:06:49 The Role Of Consciousness, Stress & Positive Thinking ... 00:13:19 What Peptide Bioregulators Actually Are ... 00:15:29 Manufacturing, Quality Control & Why Source Matters ... 00:18:24 Carnosine, Natural Extracts & The Origins Of Bioregulators ... 00:19:48 Organ Extracts, Food & Ancient Healing Traditions ... 00:23:20 Natural vs. Synthetic Bioregulators ... 00:26:19 Personalized Medicine & Why One Size Doesn't Fit All ... 00:30:00 Side Effects, Safety & Clinical Experience ... 00:37:01 Professor Cavinson's Research: Why The West Remains Skeptical ... 00:38:32 The Biggest Misconceptions About Bioregulators ... 00:44:22 Cycling Bioregulators & The Principle Of Hormesis ... 00:47:47 How Many Bioregulators Should You Take? ... 00:50:10 Oxidative Stress, Free Radicals & Aging ... 00:51:45 Do Bioregulators Reduce Oxidative Damage? ... 00:54:37 Why Quality Manufacturing Is So Difficult ... 00:57:12 Avoiding Routine As A Longevity Strategy ... 01:07:42 Practical Longevity Advice For Midlife ... 01:11:07 Our Amazing Sponsors: Blue Cannatine by Troscriptions – Precision-formulated troches designed to support sustained focus and mental clarity, helping you stay sharp through long workdays, recording sessions, travel, and everything in between. Visit troscriptions.com/NATPODCAST or use code NATPODCAST at checkout to save 10% off your first order. Quantum Upgrade – A 24/7 quantum energy streaming service designed to support energy, focus, sleep, recovery, and a more balanced nervous system, backed by placebo-controlled research showing measurable improvements in stress-related brain activity and heart rate variability. Try it free for 15 days with no credit card required at QuantumUpgrade.io and use code NAT15. Just Thrive 90-Day Probiotic – A spore-based probiotic that survives stomach acid to arrive 100% alive in your gut, supporting better digestion, nutrient absorption, immunity, and less bloating. Start your first 90-day subscription today and you'll get a FREE 90-day supply of Digestive Bitters (a $90 value) to help optimize digestion and support healthy appetite regulation. Click HERE to learn more. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode