PREECLAMPSIA AND THE OB PATIENT: PATHOPHYSIOLOGY THAT SAVES LIVES

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse anesthesia residents and CRNAs who want to feel more confident in complex pharmacology, physiology, and real-world anesthesia decision-making.

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In this episode:

• The cardiovascular, pulmonary, renal, and coagulation changes of normal pregnancy you need to know before you can recognize what's broken in preeclampsia
• Why preeclampsia is fundamentally a placenta problem that becomes a vascular endothelium problem — sFlt-1, soluble endoglin, VEGF neutralization, and the cascade that drives every symptom
• HELLP syndrome — microangiopathic hemolysis, hepatic involvement, and how it changes your anesthetic plan
• Magnesium sulfate pharmacology — NMDA antagonism, the dosing regimen, toxicity ladder, and why you must cut your non-depolarizing NMB dose by 30 to 50 percent
• Neuraxial vs general anesthesia in the severe preeclamptic — when neuraxial is safe, how to manage platelet thresholds, and how to blunt the catecholamine surge of laryngoscopy when general is unavoidable

💜 FREE DOWNLOADS: Grab your copy of customized study plans & worksheets.

• SEE/NCE Study Plan — OB pharm and physiology is high-yield on the exam — this plan tells you exactly where it fits in your prep timeline.
• Non-Opioid Pharmacology Cheat Sheet — Multimodal pain management options including the non-opioids that show up in OB anesthesia plans.
• GPCR Cheat Sheet — The receptor pharmacology behind the pressors and antihypertensives you'll be running on these patients.

💜 CONNECT: 📥 Email questions, comments or topic suggestions to Dr. Temmermand at hello@atomicanesthesia.com, follow us on social media, and sign up for our newsletter.

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