Ibogaine Uncovered8 Kesä 2023

#13 - Deborah Mash: The Lioness of Ibogaine Research

Dr. Deborah Mash is a pioneering researcher of ibogaine and one of the world’s foremost experts on the drug. She is a professor (emeritus) of neurology and molecular and cellular pharmacology at the University of Miami School of Medicine, and the founder and CEO of DemeRx, a company developing treatments for opioid use disorder.

What we discuss:

How Dr. Mash first became interested in ibogaine, including her connection to Howard Lotsof, an early ibogaine advocate
The structure of the ibogaine molecule and what makes it unique from other psychedelics
Dr. Mash’s early research: the first clinical studies of ibogaine in humans
Noribogaine: what it is and what it does
Ibogaine fatalities: is everyone who takes it is at equal risk of death?
How far have we come in terms of reframing our view of substance use disorder?
If ibogaine was rescheduled, what could the future of treatment look like?

Why it’s important:

In the excitement of the psychedelic renaissance, it can feel like all of this is “new.” It’s often said that there isn't enough research to support the use of ibogaine in a clinical setting, but Dr. Mash’s work is part of a growing body of evidence that proves otherwise. Reconciling her work and the stories you’ve heard on this show with the fact that ibogaine is still a Schedule I substance in the United States – meaning it has no medical value and a high potential for abuse – is hard to do. Understanding and working to change drug policy through research is a long game. We’re lucky that an expert like Dr. Mash is staying on the field.

Relevant Links:

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#28 - Tommy Aceto: Turning Pain into Passion

Tommy Aceto is a former US Navy Seal and intelligence officer, a father, a breakthrough therapies advocate, a writer and director, a life coach and retreat coordinator, and veteran mental health chief...

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#27 - Anthony Esposito and Amber Antonelli: How Intense is Iboga, Really?

Anthony Esposito and Amber Antonelli are the co-founders of Awaken Your Soul, an iboga retreat center in Costa Rica. Both Anthony and Amber are Bwiti initiates and iboga providers who have been workin...

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#26 - Joshua White: Peer Support in Psychedelic Therapy

Joshua White is a lawyer, peer support advocate, psychedelic researcher, and the founder and executive director of Fireside Project. He believes in the power of peer support and the role of support li...

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#25 - W. Bryan Hubbard: Lessons from Kentucky's Ibogaine Initiative

Bryan Hubbard is a lawyer and the former chairman and executive director of the Kentucky Opioid Abatement Advisory Commission (KOAAC). Tasked with allocating an $842-million settlement from opioid man...

26 Helmi 20241h 7min

#24 - Amber Capone: The Ibogaine Integration of a Navy SEAL

Amber Capone is the CEO and co-founder at Veterans Exploring Treatment Solutions (VETS). Four years ago, she walked away from a successful career in real estate to serve in these roles, determined to ...

8 Helmi 202448min

#23 - Dr. Nolan Williams: Can Ibogaine Treat Traumatic Brain Injury?

Dr. Nolan Williams is an Associate Professor within the Department of Psychiatry and Behavioral Sciences and the Director of the Stanford Brain Stimulation Lab. He is triple board-certified in general...

24 Tammi 202435min

#22 - Ben “Doc” Askins: From Straight-Edge to Psychedelic

Ben "Doc" Askins is a physician assistant, US army captain, author and podcast host. He has two decades of experience practicing and teaching wilderness, tactical, and expeditionary medicine in the mi...

14 Tammi 20241h 2min