Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome’s role in neurodevelopment and neurodegeneration, as well as how gut microbes influence neurological health, behavior, and conditions like Parkinson's, autism, and depression. He highlights the human gut microbe symbiosis, early-life microbial exposure's influence, and the adult microbiome's malleability. We explore microbiome-based therapeutics' potential, challenges in translating animal models to humans, personalized medicine's future, the microbiome's impact on drug efficacy, gut bacteria's influence on behaviors and cravings, and the importance of a healthy gut diet. Please enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll InsideTracker: Use code RICHROLL at checkout and enjoy 10% OFF the InsideTracker Subscription and any plan 👉insidetracker.com/richroll On: 10% OFF your first order of high-performance shoes and apparel w/ code RICHROLL10👉on.com/richroll Roka: Unlock 20% OFF sunglasses & eyewear with code RICHROLL 👉roka.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF my favorite non-alcoholic brews 👉gobrewing.com Squarespace: Use the offer code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll

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Plant-Based Bassist Tanya O'Callaghan On How Changing Your Plate Can Change The World

Plant-Based Bassist Tanya O'Callaghan On How Changing Your Plate Can Change The World

This week, I am joined by Tanya O’Callaghan, a musician, speaker, and activist, to discuss her unconventional journey from Ireland to a globally touring rock musician dedicated to advocacy. She talks ...

25 Huhti 20242h 4min

Jonathan Haidt On How Social Media Is Rewiring Childhood

Jonathan Haidt On How Social Media Is Rewiring Childhood

This week, I am joined by Jonathan Haidt, an NYU professor and best-selling author, to discuss the significant negative impact of technology and social media on young people’s mental health and well-b...

22 Huhti 20241h 58min

Scott Galloway on Healthy Masculinity, How to Achieve Financial Security, & Why Vulnerability Is Power

Scott Galloway on Healthy Masculinity, How to Achieve Financial Security, & Why Vulnerability Is Power

This week, I am joined by Scott Galloway, NYU professor, best-selling author, serial entrepreneur, and podcaster, to discuss the multifaceted challenges many young men face today. He underscores the l...

15 Huhti 20241h 56min

The Dean of Stanford Medical School on How AI Is Shaping The Future of Health Precision

The Dean of Stanford Medical School on How AI Is Shaping The Future of Health Precision

This week, I am joined by Dr. Lloyd Minor, the Carl and Elizabeth Naumann Dean of the Stanford University School of Medicine and Vice President for Medical Affairs at Stanford University. Dean Minor t...

11 Huhti 20241h 37min

Pause, Breathe, Reflect: How A Brush With Death Changed Michael O’Brien’s Life

Pause, Breathe, Reflect: How A Brush With Death Changed Michael O’Brien’s Life

This week, I’m joined by Michael O’Brien, a former executive, and father of two who experienced a profound transformation after a life-altering cycling accident. Previously consumed by 65-hour work we...

8 Huhti 20242h 25min

Psychiatrist Dr. Daniel Amen On All Things Brain Health, Dementia, Alzheimer’s & ADHD

Psychiatrist Dr. Daniel Amen On All Things Brain Health, Dementia, Alzheimer’s & ADHD

This week, I am joined by Dr. Daniel Amen, a world-renowned psychiatrist and bestselling author, as we delve into the intricacies of brain health and cognitive decline. From discussing the challenges ...

1 Huhti 20241h 59min

Modeling Well-Being: Gisele Bündchen On Nourishing The Self, The Soul & The Planet

Modeling Well-Being: Gisele Bündchen On Nourishing The Self, The Soul & The Planet

This week, I am joined by Gisele Bündchen, one of the world’s most recognized faces—a world-renowned supermodel, philanthropist, New York Times bestselling author, and ardent wellness advocate. Gisele...

25 Maalis 20241h 12min

Kara Goucher: Inside the Secret World of Elite Sport Doping, Abuse & Deception

Kara Goucher: Inside the Secret World of Elite Sport Doping, Abuse & Deception

This week, I am joined by Kara Goucher. She bravely shares her experiences as an athlete, including injuries, financial struggles, and her time with the Nike Oregon Project. We delve into the weight m...

21 Maalis 20242h 1min

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