Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome’s role in neurodevelopment and neurodegeneration, as well as how gut microbes influence neurological health, behavior, and conditions like Parkinson's, autism, and depression. He highlights the human gut microbe symbiosis, early-life microbial exposure's influence, and the adult microbiome's malleability. We explore microbiome-based therapeutics' potential, challenges in translating animal models to humans, personalized medicine's future, the microbiome's impact on drug efficacy, gut bacteria's influence on behaviors and cravings, and the importance of a healthy gut diet. Please enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll InsideTracker: Use code RICHROLL at checkout and enjoy 10% OFF the InsideTracker Subscription and any plan 👉insidetracker.com/richroll On: 10% OFF your first order of high-performance shoes and apparel w/ code RICHROLL10👉on.com/richroll Roka: Unlock 20% OFF sunglasses & eyewear with code RICHROLL 👉roka.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF my favorite non-alcoholic brews 👉gobrewing.com Squarespace: Use the offer code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll

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How Emily Harrington Became The First Woman To Free Climb El Cap’s Golden Gate In Under 24 Hours

How Emily Harrington Became The First Woman To Free Climb El Cap’s Golden Gate In Under 24 Hours

Emily Harrington is a professional climber who became the first woman to free climb El Capitan's Golden Gate route in under 24 hours, captured in the documentary Girl Climber. This conversation explo...

6 Loka 20252h 2min

Psychotherapist John W. Price Unpacks Ancient Wisdom For Modern Healing

Psychotherapist John W. Price Unpacks Ancient Wisdom For Modern Healing

Dr. John Price is a depth psychotherapist and co-founder of The Center for Healing Arts & Sciences. This conversation explores why men have 50% fewer friends than twenty years ago, the crisis of mode...

29 Syys 20252h 48min

Women's Health Compilation: Leading Experts On All Things Estrogen, Menopause, Fertility, & The Diet That Changes Everything

Women's Health Compilation: Leading Experts On All Things Estrogen, Menopause, Fertility, & The Diet That Changes Everything

This Women's Health and Hormones Compilation explores how estrogen regulates brain function, why 86% of mothers lose core strength with no recovery protocol, and the critical timing window for hormone...

25 Syys 20251h 3min

Olympic Legend Dara Torres: Age-Defying Fitness, Eating Disorders & Protecting The Next Generation of Gold Medal Talent

Olympic Legend Dara Torres: Age-Defying Fitness, Eating Disorders & Protecting The Next Generation of Gold Medal Talent

Dara Torres is a 5-time Olympian, 12-time Olympic medalist, and the oldest swimmer to ever win an Olympic medal at age 41. We explore how she broke American records two years after giving birth, trai...

22 Syys 20251h 37min

Psychologist Marc Brackett On Why You Can't Name Your Emotions, Cognitive Strategies For Emotional Regulation, & Giving Yourself Permission To Feel

Psychologist Marc Brackett On Why You Can't Name Your Emotions, Cognitive Strategies For Emotional Regulation, & Giving Yourself Permission To Feel

Dr. Marc Brackett is a Yale professor, founder of the Yale Center for Emotional Intelligence, and creator of the RULER program implemented in 5,000 schools worldwide. This conversation explores Marc'...

15 Syys 20252h 28min

Beyond Eat, Pray, Love: Elizabeth Gilbert's Raw Truth About Addiction, Codependency & The Awakening That Saved Her Life

Beyond Eat, Pray, Love: Elizabeth Gilbert's Raw Truth About Addiction, Codependency & The Awakening That Saved Her Life

Elizabeth Gilbert is the bestselling author of "Eat, Pray, Love" and her new memoir "All the Way to the River." This conversation explores sex and love addiction, her partner's death during relapse, ...

11 Syys 20252h 25min

Rhett & Link On Building A (Mythical) Media Empire, The Price of Public Friendship, & Leaving The Evangelical Church

Rhett & Link On Building A (Mythical) Media Empire, The Price of Public Friendship, & Leaving The Evangelical Church

Rhett McLaughlin and Link Neal are the creators of Good Mythical Morning, one of YouTube's most-watched daily shows with over 19 million subscribers and 8 billion views. This conversation explores th...

8 Syys 20252h 11min

Jay Duplass & Michael Strassner On The Art of Creative Rebellion

Jay Duplass & Michael Strassner On The Art of Creative Rebellion

Jay Duplass is an award-winning filmmaker, actor, and co-architect of the mumblecore movement. Michael Strassner is a comedian, actor, and the protagonist of Jay's new film "The Baltimorons." This co...

1 Syys 20252h 31min

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