Single-Cell Technologies using Microfluidics (Ben Hindson, CSO of 10x Genomics)
Epigenetics Podcast16 Maalis 2022

Single-Cell Technologies using Microfluidics (Ben Hindson, CSO of 10x Genomics)

In this episode of the Epigenetics Podcast, we caught up with Ben Hindson, Chief Scientific Officer at 10X Genomics, to talk about single-cell technologies using microfluidics.

Epigenetics has moved well past a simple understanding of a single epigenetic layer of control at genomic regions of interest, thanks to advances in many techniques and the application of “multiomics”. We can now analyze genome-wide histone modification patterns, transcription factor binding profiles, chromatin accessibility profiles, three-dimensional chromosomal conformation, and DNA methylation dynamics combined with transcriptomic analyses and associated analytical platforms.

Bulk Assays, like ATAC-Seq or ChIP, despite all their advantages, do not provide information about the chromatin states of individual subpopulations of cells within a sample. To identify chromatin features in heterogeneous populations, such as blood, pancreas, and brain, those analysis need to be performed at a single-cell level. 10X Genomics has been at the forefront of the movement into the single cell space and in this Episode we discuss this work with Ben Hindson, CSO of 10X genomics.

References

Related Episodes

Contact

Jaksot(171)

The Role of H3K4me3 in Embryonic Development (Eva Hörmanseder)

The Role of H3K4me3 in Embryonic Development (Eva Hörmanseder)

In this episode of the Epigenetics Podcast, we talked with Dr. Eva Hörmanseder from the HelmholtzZentrum in Munich about her work on epigenetic mechanisms in cellular memory and gene regulation. In th...

27 Maalis 202537min

Using RICC-Seq to Probe Short Range Chromatin Folding (Viviana Risca)

Using RICC-Seq to Probe Short Range Chromatin Folding (Viviana Risca)

In this episode of the Epigenetics Podcast, we talked with Viviana Risca from Rockefeller University about her work on RICC-Seq and how it's used to probe DNA-DNA contacts in intact or fixed cells usi...

13 Maalis 202546min

The Mechanism of ATP-dependent Remodelers and HP1 Gene Silencing (Geeta Narlikar)

The Mechanism of ATP-dependent Remodelers and HP1 Gene Silencing (Geeta Narlikar)

In this episode of the Epigenetics Podcast, we talked with Geeta Narlikar from UCSF about her work on chromatin remodeling, Heterochromatin Protein 1, and the molecular mechanisms that influence the g...

27 Helmi 202539min

Polycomb Proteins, Gene Regulation, and Genome Organization in Drosophila (Giacomo Cavalli)

Polycomb Proteins, Gene Regulation, and Genome Organization in Drosophila (Giacomo Cavalli)

In this episode of the Epigenetics Podcast, we talked with Giacomo Cavalli from the Institute of Human Genetics in Montpellier about his work on critical aspects of epigenetic regulation, particularly...

13 Helmi 202544min

The Interplay of Nutrition, Metabolic Pathways, and Epigenetic Regulation (Ferdinand von Meyenn)

The Interplay of Nutrition, Metabolic Pathways, and Epigenetic Regulation (Ferdinand von Meyenn)

In this episode of the Epigenetics Podcast, we talked with Ferdinand von Meyenn from ETH Zürich about his work on the interplay of nutrition, metabolic pathways, and epigenetic regulation. To start Dr...

23 Tammi 202548min

Single-Molecule Adenine Methylated Oligonucleosome Sequencing Assay (SAMOSA) (Vijay Ramani)

Single-Molecule Adenine Methylated Oligonucleosome Sequencing Assay (SAMOSA) (Vijay Ramani)

In this episode of the Epigenetics Podcast, we talked with Vijay Ramani from the Gladstone Institute about his work on Single-Molecule Adenine Methylated Oligonucleosome Sequencing Assay (SAMOSA). Our...

9 Tammi 202552min

Epigenetic Consequences of DNA Methylation in Development (Maxim Greenberg)

Epigenetic Consequences of DNA Methylation in Development (Maxim Greenberg)

In this episode of the Epigenetics Podcast, we talked with Maxim Greenberg from the Institute Jacob Monot about his work on epigenetic consequences of DNA methylation in development. In this interview...

19 Joulu 202444min

R-Loop Biology in Health and Disease (Natalia Gromak)

R-Loop Biology in Health and Disease (Natalia Gromak)

In this episode of the Epigenetics Podcast, we talked with Natalia Gromak from the University of Oxford about her work on R-Loop biology in health and disease. In this interview Dr. Gromak delves into...

5 Joulu 202429min

Suosittua kategoriassa Tiede

rss-mita-tulisi-tietaa
tiedekulma-podcast
rss-poliisin-mieli
utelias-mieli
rss-duodecim-lehti
mielipaivakirja
rss-metsantuntijat-podcast
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
university-of-eastern-finland
docemilia
vinkista-vihia
rss-vaasan-yliopiston-podcastit
rss-duokkari-ekstra
rss-astetta-parempi-elama-podcast
rss-tiedetta-vai-tarinaa
rss-pandapodi
rss-lapsuuden-rakentajat-podcast
rss-miljonaarien-tasavalta