High Cortisol Mysteries Unveiled, The Adrenal Fatigue Myth, Advanced Lab Blood Testing & More!
Boundless Life2 Heinä 2016

High Cortisol Mysteries Unveiled, The Adrenal Fatigue Myth, Advanced Lab Blood Testing & More!

Note: There is a special addendum at the end of this podcast episode in which Ben mentions the book "Ego Is The Enemy", this sermon on Time & Resources by a man named Toby Sumpter and the practice of iridology. Last month, I released the podcast episode entitled "Why Is My Cortisol High Even Though I’m Doing Everything Right? Hidden Causes Of High Cortisol, The DUTCH Test & More!".

In that episode with fellow podcaster and health consultant Chris Kelly, we delved into the mystery of why cortisol can be so high in someone such as myself who sleeps well, does meditation, yoga, and lives a relatively stress-free life. It was a fascinating, extremely popular episode, but created just as many questions as it answered about what really causes high cortisol in people, and whether it's something you even need to worry about in the first place!

To delve into the cortisol mystery more, after that episode, Chris Kelly introduced me to Dr. Bryan Walsh, a naturopathic doctor from Maryland, with an amazing series of WellnessFX lab testing interpretation videos on YouTube. Dr. Walsh has an extremely sharp mind, an extensive fitness background, a degree in naturopathic medicine, and a host of additional training and certifications. His wife is a naturopath too, so his children are probably some of the healthiest on the planet. When tough cases or head-scratching lab results arise, Dr. Walsh turns from mild-mannered dad and husband into forensic physiologist, pulling out his microscope to analyze blood, saliva, urine, lifestyle and whatever else he has to, in order to solve the medical mystery. Dr. Walsh ran an extensive series of follow-up lab tests on me, primarily through the laboratory testing services of another functional medicine practitioner - a chiropractor in Atlanta, Georgia named Dr. Brady Hurst. At his company, TrueHealthLabs, Dr. Hurst uses advanced laboratory tools to uncover hidden dysfunctions and uses primarily drugless treatment plans to restore those dysfunctions. TrueHealthLabs has a number of direct-to-consumer tests that are not traditional lab tests and can instead be custom panels that a doctor or patient can order. They even offer some functional lab testing in Europe.

In this episode, Dr. Brady Hurst, Dr. Bryan Walsh and I completely geek out on the high cortisol lab testing results and during our discussion, you'll discover: -The secret ingredients the green morning smoothie that Dr. Bryan gives to his young children... -How to keep your morning green smoothie from getting oxidized or damaged by the blender... -The seven stage home filtration process Dr. Brady uses to filter his water... -The very first additional hormone you should test for if you find out your cortisol is high... -The best lab panel to look at whether or not your body is actually producing adequate antioxidants... -When high HDL (commonly known as good cholesterol) can actually be a bad thing... -How high cortisol down-regulates your metabolism and your insulin sensitivity and puts your body into fat storage mode... -Why thyroid replacement medications or natural thyroid supplements rarely work to fix the thyroid... -When you don't need to actually worry about high liver enzymes on a blood lab test... -The hidden laboratory marker that can tell you if you need to be consuming more sea salt and minerals... -How to tell if your body has excess oxidative stress, and what you can do about it... -And much more!

Resources from this episode: -iSpring Reverse Osmosis filter -Apex Energetics supplements that Dr. Brady uses -Liposomal glutathione -Article: How To Biohack Your Green Smoothie (And Can High Speed Blenders Really Damage Your Food?) -DUTCH Urine Steroid Hormone Profile -Ben Greenfield’s DUTCH test results -TrueHealthLabs Oxidative Stress Profile -Ben Greenfield's Oxidative Stress Profile results -TrueHealthLabs Custom Lab Testing - Ben tested the following: a. NMR Lipoprofile b. Oxidized LDL c. ACTH, cortisol, and aldosterone d. LH, FSH e. Free and total testosterone f. Prolactin g. C-peptide -Ben Greenfield's TrueHealthLabs Custom Lab Testing results Extra Notes: After our call, in a flurry of e-mails, Dr. Walsh also recommended the following follow up tests:

  1. Lymphocyte subset panel (CD4/CD8) – Your lymphocytes are relatively low compared to your neutrophils, so I’m not sure it would show much, but this panel shows ratios of lymphocytes, regardless of their total levels, and could offer a little info.
  2. Cytokine panel – I’m a little hesitant on the accuracy of these panels, but they are used in research, so I think they are accurate enough for our purposes. This might show a tendency for a Th1/Th2/Th17 shift, which could be interesting to know. High cortisol is often associated with a Th2 dominance, which this panel would theoretically show. If it were me, I’d be curious about the results of this panel.
  3. Neopterin – This is a huge stretch, but I personally love this marker. When neopterin is elevated, it suggests an Th1 response due to activated macrophages. If I had to bet money, I’d say this would come back normal for you but again, medicine attempts to rule out things first, and this would rule out any Th1 involvement.
  4. I don’t suspect any autoimmunity in you, but if you’re getting your blood drawn anyways, you could run something like ANA. This won’t identify all autoimmune conditions, but some. I’m on the fence about this marker.
  5. There’s one other marker you could run, but I would only run it for educational purposes for your listeners, and that is Glycomark, also known as 1,5 anhydroglucitol. This is one of my favorite markers of all time, because it measures postprandial glucose levels two weeks prior to the test, which is just awesome. I suspect that this marker, when abnormal, is the first of the glucose regulatory markers to show tendencies for glucose dysregulation, far before fasting glucose, c-peptide, or A1C.
  6. Cyrex panels – You mentioned this on the call. If you’re truly using yourself as an experiment for the benefit of listeners, you could run their antibody panel and/or their intestinal permeability panel. I know you’ve had some gut issues in the past, so the latter might be of interest. For the average patient, we usually use these when things aren’t resolving well, but for myself, if money weren’t an issue and I was truly doing an experiment, I’d run these panels to see what came up.
  7. If you’ve indeed had elevated cortisol for a few years now, and possibly elevated ACTH, it may be that you actually have enlarged adrenal glands capable of making more hormones. Here’s the thought process. ACTH is a “trophic” hormone, meaning it enlarges its target organ (adrenals). Not only that, the cells of the three layers of the adrenal glands can be repurposed for making different hormones than they were designed to. For example, cells in the outer-most layer of the cortex (glomerulosa) normally make aldosterone. But in the presence of sustained and elevated ACTH, the cells of the glomerulosa can morph into fasiculata cells, which normally make more cortisol. Thus, it may not only take less ACTH to stimulate cortisol release, but if the cells of the glomerulosa are repurposed, they will make less aldosterone, which is something you’re seeing on your lab as well. If you did want to ask a doc to humor you and get an ultrasound on your liver, you can see if they would be willing to do it on your adrenal glands as well. There are cash-based ultrasound clinics around and you wouldn’t even need a doctor’s recommendation.

Do you have questions, comments or feedback for Dr. Brady Hurst from TrueHealthLabs, Dr. Bryan Walsh or Ben Greenfield? Leave your thoughts at BenGreenfieldFitness.com and one of us will reply!

See omnystudio.com/listener for privacy information.

Jaksot(1746)

Mushroom Mastery & Beyond: A Practical, How-To Guide For Unlocking New Parts Of Your Brain, Thinking Faster & Enhancing Performance With The Science Of Microdosing.

Mushroom Mastery & Beyond: A Practical, How-To Guide For Unlocking New Parts Of Your Brain, Thinking Faster & Enhancing Performance With The Science Of Microdosing.

My guests on today's show—Dr. James Fadiman and Jordan Gruber—just released the brand new book Microdosing for Health, Healing and Enhanced Performance, which is the first comprehensive book on microdosing, using new research and extensive reports from individuals to describe the possibilities of the practice. Full show notes: https://bengreenfieldlife.com/microdosingpodcast Episode Sponsors: Just Thrive: For a limited time, you can save 20% off a 90-day bottle of Just Thrive Probiotic and Just Calm at justthrivehealth.com/ben with promo code BEN. That’s like getting a month for FREE! Take control today with Just Thrive! LVLUP Health: I trust and recommend LVLUP Health for your peptide needs, as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for 15% off on their game-changing range of products. LeelaQ: Not only do LeelaQ’s products neutralize EMF, increase ATP production, optimize HRV, and improve blood flow, but they've been third-party proven to do so in placebo-controlled double-blind studies. Visit leelaq.com/ben and use code BEN10 for 10% off. CAROL Bike: The science is clear—CAROL Bike is your ticket to a healthier, more vibrant life. And for a limited time, you can get $100 off yours with the code BEN. Don't wait any longer, join over 25,000 riders and visit carolbike.com/ben today. ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15 when you use code BEN15.See omnystudio.com/listener for privacy information.

20 Helmi 20251h 4min

Is This The Healthiest Steak In The World? The *Crazy* Story Of How One Breed Of Cattle Became A Protein Powerhouse (& How You Can Get It!) With Justin Owens.

Is This The Healthiest Steak In The World? The *Crazy* Story Of How One Breed Of Cattle Became A Protein Powerhouse (& How You Can Get It!) With Justin Owens.

My guest on today's show is farmer Justin Owens, who I recently met on an intriguing trip out to his farm near Spokane. His company Manzo is the first beef label in North America to exclusively produce Fassone, beef from the Italian cattle breed, Fassona—known in North America as Piedmontese. Manzo is solely produced on Justin's ranch in Spokane, Washington, at Owens Farms. Everything is done in-house up to harvest, from breeding to birth to finishing! Full show notes: https://bengreenfieldlife.com/beefpodcast Episode Sponsors: RoXiva: Try out this world-class multisensory RX1 lamp, featuring meticulously crafted light and sound journeys that guide you effortlessly and reliably into new and expanded states of awareness. Get yours now by going to roXiva.com/ben! NOVOS: Unlock your potential for a longer, healthier life with NOVOS Core, the scientifically validated anti-aging formula targeting all 12 causes of aging to enhance sleep, energy, mood, cognition, and skin health. Visit novoslabs.com and use code BEN10 for 10% off your first month’s subscription—start your longevity journey today! Ancient Crunch: Introducing the best guilt-free snack on the market: classic, seed oil-free tortilla chips with only three natural ingredients. Go to masachips.com/bengreenfield and get 20% off your first order! Organifi Green Juice: Reset your body with Organifi Green Juice! With 11 superfoods, 600mg of ashwagandha, and certified organic ingredients, it curbs cravings, supports stress, and fuels your day. Go to organifi.com/Ben for 20% off! Ketone-IQ: Ketones are a uniquely powerful macronutrient that can cross the blood-brain barrier and increase brain energy and efficiency. With a daily dose of Ketone-IQ, you'll notice a radical boost in focus, endurance, and performance. Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG. See omnystudio.com/listener for privacy information.

15 Helmi 20251h 1min

Bloodwork, Biomarkers, Biohacking Las Vegas, Optimizing Performance and Longevity & More With UFC Fighter Miesha Tate

Bloodwork, Biomarkers, Biohacking Las Vegas, Optimizing Performance and Longevity & More With UFC Fighter Miesha Tate

In this dual-release episode with Boundless Life and Miesha Tate’s Built for Growth, you’ll get to explore the cutting-edge strategies that top athletes and high-performers use to optimize their bodies and minds. This fascinating conversation dives into the power of comprehensive blood testing, hormonal balance, and genetic assessments for longevity and peak performance. You’ll also discover the latest in biohacking recovery tools—hyperbaric oxygen therapy, red light therapy, PEMF technology—and how they can accelerate recovery and enhance resilience. Whether you're an elite athlete or simply looking to take your health to the next level, this conversation is packed with practical, science-backed insights you can apply right away. Full show notes: https://bengreenfieldlife.com/tatepodcast Episode Sponsors: Force of Nature: Unlock 20% off your order at Force of Nature! Use code BEN at checkout for premium, responsibly sourced meats (minimum purchase of $189 required). Shop now: forceofnature.com/discount/BEN. Timeline Nutrition: Timeline is offering 10% off your first order of Mitopure—vegan softgels designed to provide the recommended dose of Urolithin A for boosted cellular health. Go to timelinenutrition.com/BEN and use code BEN to get 10% off your order. Analemma: To experience the science-backed power of coherent water for yourself, visit analemma-water.com and use code BENG for 10% off! Birch Living: Transform your sleep with a Birch mattress! Enjoy deep, restful nights with 20% off sitewide, plus 2 free Eco-Rest Pillows. Visit birchliving.com/bengreenfield to upgrade your sleep today! BEAM Minerals: If you want to up your mineral game, give BEAM Minerals a try. Go to beamminerals.com and use code BEN at checkout for 20% off your order. Lumen: Optimize your metabolism with Lumen's handheld metabolic coach! Gain personalized insights for better energy, weight management, fitness, and sleep. Lumen even adapts to hormonal changes to keep you feeling your best. Take the next step at lumen.me/GREENFIELD and get 20% off!See omnystudio.com/listener for privacy information.

13 Helmi 20251h 3min

What's The Blood Of Very Healthy Old People Look Like?, Time-Hacking Exercise, The Best Way To "Filter Your Blood" & More—Q&A 485

What's The Blood Of Very Healthy Old People Look Like?, Time-Hacking Exercise, The Best Way To "Filter Your Blood" & More—Q&A 485

In this episode, you’ll get to discover groundbreaking insights and practical strategies to optimize your health, longevity, and performance. You’ll explore a fascinating study on centenarians, revealing how specific blood biomarkers—like higher cholesterol and iron levels, along with lower glucose and liver enzymes—can serve as powerful predictors of longevity and help you personalize your health approach. Ready to dig into a treasure trove of actionable advice and intriguing science, aimed at helping you become the most complete, boundless version of yourself? Full show notes: https://bengreenfieldlife.com/485 Episode Sponsors: Peluva: Visit Peluva.com and use code BEN for 15% off your first pair of barefoot minimalist shoes—Peluva's let your feet be feet! BIOptimizers Magnesium Breakthrough: The 7 essential forms of magnesium included in this full spectrum serving help you relax, unwind, and turn off your active brain after a long and stressful day so you can rest peacefully and wake up feeling refreshed, vibrant, and alert. Go to bioptimizers.com/ben and use code ben10 for 10% off any order. Our Place: Upgrade to Our Place today and say goodbye to forever chemicals in your kitchen with their iconic, multifunctional cookware. Go to fromourplace.com and enter my code BEN at checkout to receive 10% off sitewide. SuppCo: Get early FREE access to SuppCo's supplement management app during its beta phase by visiting supp.co/BEN. Plus, podcast listeners will unlock early access to SuppCo’s founding membership when it launches in early 2025. Feno: Transform your oral health with the Feno Smartbrush, the AI-powered device that delivers a perfect clean in just 20 seconds with 18,000 bristles and personalized insights for your whole-body health. Visit feno.co and use code BEN for $50 off—elevate your brushing routine today!See omnystudio.com/listener for privacy information.

8 Helmi 202537min

How Ben Greenfield Crafts His Daily Routine, His Best Tips For Transforming Your Life From Chaos To Order & The History Of Building A Fitness Empire, With "The Financial Dad Podcast."

How Ben Greenfield Crafts His Daily Routine, His Best Tips For Transforming Your Life From Chaos To Order & The History Of Building A Fitness Empire, With "The Financial Dad Podcast."

In this fascinating episode, you’ll get to explore the balance between business success, personal well-being, and family harmony in a special dual release with The Financial Dad podcast, hosted by father-daughter duo Tim Smith and Hally Smith. I’ll share how I built my successful ventures, including Kion and Ben Greenfield Life, and how my entrepreneurial journey—from selling Halloween candy as a kid to launching a revolutionary sports medicine facility—shaped my approach to health, business, and family. Whether you're an entrepreneur, a business owner, or simply looking for ways to optimize your health, finances, and lifestyle, this episode is packed with actionable takeaways to help you take control and live a boundless life with your family. Tune in now for this inspiring conversation with The Financial Dad! Full show notes: https://bengreenfieldlife.com/tfd Episode Sponsors: Quantum Upgrade: Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Just Thrive: For a limited time, you can save 20% off a 90-day bottle of Just Thrive Probiotic and Just Calm mood support at justthrivehealth.com/ben with promo code BEN. Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. Lumen: Optimize your metabolism with Lumen's handheld metabolic coach! Gain personalized insights for better energy, weight management, fitness, and sleep. Lumen even adapts to hormonal changes to keep you feeling your best. Take the next step at lumen.me/GREENFIELD and get 20% off! NOVOS: Visit www.novoslabs.com and use code BEN10 for 10% off your first month’s subscription—start your longevity journey today!See omnystudio.com/listener for privacy information.

6 Helmi 202550min

Why Running *Isn't* The Best Way To Get Fit, How The Running Craze HARMED Fitness Enthusiasts & Why Walking Is Essential To Health & Longevity, With Mark Sisson.

Why Running *Isn't* The Best Way To Get Fit, How The Running Craze HARMED Fitness Enthusiasts & Why Walking Is Essential To Health & Longevity, With Mark Sisson.

The romanticized notion that humans are "born to run" has buoyed the so-called running boom of the past 50 years: well-intentioned fitness enthusiasts lacing up their cushioned shoes and plodding down roads and trails in pursuit of the runner's high, a trim physique, and the fountain of youth. Unfortunately, "born to run" is a big, fat ruse—a marketing gimmick and a gross misappropriation of evolutionary biology's insights into Homo sapiens' genetic attributes for endurance. While any movement away from a sedentary-dominant lifestyle is laudable, the truth is that humans are actually born to walk, not run. Ready to get fitter, leaner, and stronger than ever without the pain, suffering, and sacrifice of the typical approach to endurance training? Full show notes: https://bengreenfieldlife.com/borntowalk Episode Sponsors: LVLUP Health: Head over to lvluphealth.com/BGL for a special discount on their game-changing range of products. Fatty15: Boost your health and longevity with Fatty15! Get 15% off their 90-day subscription Starter Kit. Visit fatty15.com/BEN and use code BEN at checkout to start your journey today! Hiya: Receive 50% off your first order. To claim this deal you must go to hiyahealth.com/BEN. This deal is not available on their regular website. Sunlighten: Save $600 or more today and start biohacking your mind, body, and spirit at get.sunlighten.com/ben! Force of Nature: Unlock 20% off your order at Force of Nature! Use code BEN at checkout for premium, responsibly sourced meats. Minimum $189 purchase required. Shop now: https://forceofnature.com/discount/BEN.See omnystudio.com/listener for privacy information.

1 Helmi 202558min

How To Heal From Surgeries Faster, The Fringe "Antihistamine Sleep Hack," Methylene Blue Nasal Spray & Much More With Tim Gray.

How To Heal From Surgeries Faster, The Fringe "Antihistamine Sleep Hack," Methylene Blue Nasal Spray & Much More With Tim Gray.

In this episode with Tim Gray, you'll get to explore the cutting-edge world of biohacking and health optimization as Tim shares his journey of overcoming severe dental and jaw issues through advanced biological dentistry and surgery. You'll also discover recovery practices like grounding, quality sleep, and managing histamine with ketotifen, alongside the transformative benefits of high-dose collagen, amino acids, and peptides for hormone restoration. Additionally, Tim dives into the power of laser and red light therapy, innovative tools like methylene blue sprays for infection, and tracking recovery through heart rate variability, sleep metrics, and advanced body composition devices. Plus, you'll get a preview of the upcoming Health Optimisation Summit in Austin, featuring top experts, groundbreaking tools, and a celebration of holistic health and wellness. Whether you're a biohacker or just curious about optimizing your health, this episode is packed with valuable tips and insights. So, sit back, relax, and get ready to elevate your wellness game! Full show notes: https://bengreenfieldlife.com/texastim Episode Sponsors: Analemma: To experience the science-backed power of coherent water for yourself, visit analemma-water.com and use code BENG for 10% off! Ancient Crunch: Introducing the best guilt-free snack on the market: classic, seed oil free tortilla chips with only 3 natural ingredients. Go to masachips.com/bengreenfield and get 20% off your first order! Peluva: Experience the freedom of natural movement with Peluva, the zero-drop minimalist shoe that combines a barefoot feel with just the right cushioning for everyday life, fitness, and beyond. Try them risk-free at Peluva.com and use code BEN for 15% off your first pair—let your feet be feet! Hoolest: Take control of your brain in seconds with VeRelief Prime, the compact device that instantly shifts you from stress to calm or brain fog to sharp focus by stimulating your vagus nerve. Visit hoolest.com/ben for an exclusive discount—reset your mind anytime, anywhere! SuperTeeth: One the first oral care brands that creates products that safely remineralize teeth without the need for fluoride. Visit GetSuperTeeth.com and use code BENGREENFIELD for 15% off. IM8: Ditch the cabinet full of supplements—IM8 packs 92 powerhouse ingredients into one delicious scoop for all-day energy, gut health, and cellular support. Go to IM8Health.com and use code BEN for an exclusive gift—fuel your body the right way!See omnystudio.com/listener for privacy information.

30 Tammi 20251h

A Brand New, At-Home Way To Accurately Test Your *Mitochondrial* Health & Efficiency (Your Doctor Probably HASN'T Heard Of This!) With Dr. Hemal Patel

A Brand New, At-Home Way To Accurately Test Your *Mitochondrial* Health & Efficiency (Your Doctor Probably HASN'T Heard Of This!) With Dr. Hemal Patel

I recently discovered that there is actually an accurate method of figuring out how healthy your mitochondria are. It's called "mescreen," and it is based on groundbreaking research that allows you to assess mitochondrial function through a simple at-home blood test. Mescreen decodes your cellular performance to unlock the peak potential for optimal living. This is more than guesswork, it's the first-of-its-kind, precision pathway to discover your vitality based on your mitochondrial efficiency. Dr. Hemal Patel, my guest on this show, is a tenured professor and vice-chair for research in the Department of Anesthesiology at the University of California, San Diego, and has a dual appointment as a VA research career scientist and VA research pharmacologist at the VA San Diego Healthcare System. He is also the chief scientific advisor for Verséa Discovery (the creators of mescreen). He obtained his Ph.D. in pharmacology and toxicology from the Medical College of Wisconsin and did postdoctoral work at UCSD in the Department of Pharmacology under Paul Insel (2002–2005). He has made seminal contributions in shaping new investigation areas on defining the impact of membrane structure on cell, organ, and organismal physiology and metabolism with implications for cardiac ischemia-reperfusion injury, heart failure, diabetic cardiomyopathy, aging, pulmonary hypertension, cancer, and neurodegeneration. His focus on energetics in cell biology touches upon all these and is a control point for managing and empowering human health resilience. Full show notes: https://bengreenfieldlife.com/mescreenpodcast Episode Sponsors: BON CHARGE: BON CHARGE is a holistic wellness brand with a wide range of products that naturally address the issues of modern life. They can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%. Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with code BEN15 at quantumupgrade.io. LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL for a special discount on their game-changing range of products. Organifi Shilajit Gummies: Harness the ancient power of pure Himalayan Shilajit anytime you want with these convenient and tasty gummies. Get them now for 20% off at organifi.com/Ben. Our Place: Upgrade to Our Place today and say goodbye to forever chemicals in your kitchen. Go to fromourplace.com and enter my code BEN at checkout to receive 10% off sitewide. See omnystudio.com/listener for privacy information.

25 Tammi 202552min

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