How To Get 6 Gigabytes Of Data From Your Gut: The Fascinating Future Of Stool, Blood, Saliva & Urine Testing (From The Comfort Of Your Own Home).
Boundless Life26 Tammi 2019

How To Get 6 Gigabytes Of Data From Your Gut: The Fascinating Future Of Stool, Blood, Saliva & Urine Testing (From The Comfort Of Your Own Home).

Imagine an all-encompassing platform that allows you to keep track of all your blood, stool, saliva, and urine testing results, along with self-quantified data from wearables, and even pulls in all health testing you've done in the past as part of a single dashboard. And imagine that platform could then use highly advanced artificial intelligence to tell you exactly how to eat, how to supplement, how to exercise and much more.

All from the comfort of your home, without needing to drive to an expensive lab for multiple blood draws or fill out confusing paperwork. That's exactly what the brand new company Onegevity Health has the money, technology and data to do, and so I decided it was high time I sat down with their two chief scientists to learn exactly how this process works. I've already sent in my own stool using their Gut/bio shotgun stool sequencing test that we discuss in this episode.

My guests are Dr. Joel Dudley and Dr. Chris Mason. These guys are highly qualified and wicked smart.

Dr. Dudley is currently Associate Professor of Genetics and Genomic Sciences, Endowed Chair of Biomedical Data Science, and founding Director of the Institute for Next Generation Healthcare at the Icahn School of Medicine at Mount Sinai. Prior to Mount Sinai, he held positions as Co-founder and Director of Informatics at NuMedii, Inc. and Consulting Professor of Systems Medicine in the Department of Pediatrics at Stanford University School of Medicine.

His work, published in >120 peer-review publications, is focused at the nexus digital health, artificial intelligence (AI), scientific wellness, and healthcare delivery. His work has been featured in the Wall Street Journal, Scientific American, MIT Technology Review, CNBC, and other popular media outlets. He was named in 2014 as one of the 100 most creative people in business by Fast Company magazine. He is co-author of the book Exploring Personal Genomics from Oxford University Press. Dr. Dudley received a BS in Microbiology from Arizona State University and an MS and PhD in Biomedical Informatics from Stanford University School of Medicine.

Dr. Christopher Mason is currently an Associate Professor at Weill Cornell Medicine, with appointments at the Tri-Institutional Program in Computational Biology and Medicine between Cornell, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medicine, the Sandra and Edward Meyer Cancer Center, and the Feil Family Brain and Mind Research Institute. He is also Director of the WorldQuant Initiative for Quantitative Prediction, which bridges prediction methods in finance with genomics. His work spanning >140 peer-reviewed publications has been featured on the cover of Science, Nature, and Cell journals as well as the New York Times, Wall Street Journal, CNN, Forbes, and other major media outlets.

Dr. Mason was featured as a speaker at TEDMED and he was recognized in 2014 as one of the “Brilliant Ten” by Popular Science magazine. He completed his dual B.S. in Genetics and Biochemistry (2001) from University of Wisconsin-Madison, his Ph.D. in Genetics (2006) from Yale University, and then completed post-doctoral training in clinical genetics (2009) at Yale Medical School while jointly a post-doctoral Fellow of Genomics, Ethics, and Law at Yale Law School (2009).

During the show, you'll discover: -What Onegevity is, and what it does...9:45
  • "Health intelligence" company
  • History of the company
    • Frustration with how long it takes research to reach the consumer
    • 17 years to reach just the clinic; many years after that to reach the consumer
  • How is it different from other biome testing companies
    • Shotgun sequencing vs. 16S
    • Translate the results along with actionable steps to take
    • Recreational health information vs. health management companies
    • Vertically integrated with Thorne, who develops the actual solutions
    • Starting over in some ways in the realm of microbiome testing
-What is metatranscriptome analysis?...18:00
  • "Meta" = Across all species
  • DNA + RNA analysis
  • Challenges with RNA analysis - some clinicians consider it useless
  • Only top few % of species generate RNA in the sample
  • Comparable in price to shotgun sequencing
-The actual testing process at Onegevity...20:45
  • Very small stool sample required, as compared to other tests
  • 6 gigabytes of data after sequencing DNA
  • Each fragment compared to all known species on earth
  • Interactive report on the web; suggestions on what food and supplements to order
  • Network modeling:
    • How are changes in the microbiome propagating to the blood
    • More comprehensive than guessing based on correlations
  • What is measured in the blood?
    • TBD based on the individual's health
-How Joel and Chris overcome challenges and skepticism in their testing processes...28:20
  • How can you measure the whole gut with a stool sample? (Spatial microbiome testing)
  • Not necessary, even harmful, to sample from other areas of the gut
-The role of artificial intelligence (AI) in the testing process at Onegevity...36:40
  • Predicts diseases/conditions based on the shotgun sequencing
  • Recommend foods and supplements to consume
  • Each company has its own variables, testing protocols, etc.; results in differing test results
  • Database continues to grow with each test; data becomes more reliable
  • Data is not for sale to outside parties; will partner under the right conditions
-How do you go from stool, to shotgun sequencing, to "don't eat green beans?"...40:35
  • Internal trial; shocking results
  • Can determine the efficacy of the test at certain benchmarks; 15 day, 30 day, etc.
  • Very positive feedback from those who were tested
  • Does Thorne produce a special probiotic that seeds the gut?
-How comprehensive are the dietary recommendations after a Onegevity test?...48:52
  • Not simply a particular diet, i.e. Mediterranean, Ketogenic, etc.
  • Can make specific food, meal recommendations
  • Possibly partner with food delivery services to provide customized options
  • Very close to being perfectly genetically tailored in both microbiome and saliva tests
-How customer data is protected if Joel and Chris choose to partner with a pharmaceutical company...55:20
  • Customers are opted out by default; can choose to opt in.
  • Potential to benefit monetarily by opting in
-What the Onegevity platform looks like from a user standpoint...1:01:55 -And much more! Resources from this episode:

-Click here to visit OnegevityHealth.com for the testing we discuss in this episode. Use discount code BEN20 to receive $20 off your own test.

-Book: Exploring Personal Genomics by Joel Dudley

Episode Sponsors:

-Kion My own company where I develop coffees, energy bars and supplements. I'm also proud to endorse the Thorne line of supplements, including the multi-vitamin, which I take every day.

-Organifi Gold Wake up each day feeling rested. Relax your body after a long day. Help stiff joints feel young again. Use discount code “greenfield” and get 20% off your entire order!

-Thrive Market Your Favorite Organic Foods and Products. Up to 50% Off. Delivered to Your Door. Use my link and get an extra 25% off your first order.

-PuraThrive Keto Balance Gently push your body into Ketosis in a healthy manner so your body turns into a fat-burning machine (and stays in fat-burning mode). Get 15% off your order when you use my link.

Do you have questions, thoughts or feedback for Joel, Chris or me? Leave your comments at http://bengreenfieldfitness.com/onegevity and one of us will reply!

See omnystudio.com/listener for privacy information.

Jaksot(1746)

Vaccines?! Between a Shot & a Hard Place: Are Childhood Vaccines SAFE, How Many Do Kids Really Need & What Parents Should Ask, with Dr. Joel Warsh

Vaccines?! Between a Shot & a Hard Place: Are Childhood Vaccines SAFE, How Many Do Kids Really Need & What Parents Should Ask, with Dr. Joel Warsh

In this episode with Dr. Joel “Gator” Warsh, you’ll discover a balanced perspective on vaccines, especially childhood vaccination, at a time when open, evidence-based dialogue is more important than ever. Drawing on his work as an integrative pediatrician, Dr. Warsh shares insights from his new book Between a Shot and a Hard Place, designed not to fuel division but to empower parents with knowledge, research, and practical tools for making informed decisions. You’ll explore the origins and evolution of vaccines, how schedules have changed, the strengths and flaws of safety testing, the nuanced risks and benefits of individual shots, and the importance of informed consent and medical freedom. By weaving together mainstream medicine and holistic practices, Dr. Warsh highlights where the science is strong, where questions remain, and why open conversation is the path toward clarity, confidence, and compassion—and if you’re interested in cutting through fear and hype to understand this complex topic, you won’t want to miss this episode. Dr. Joel "Gator" Warsh is the creator of the parenting Instagram account @drjoelgator and a board-certified pediatrician in Los Angeles specializing in wellness and integrative medicine. He is the author of multiple books, including his latest Between a Shot and a Hard Place: Tackling Difficult Vaccine Questions with Balance, Data, and Clarity. He grew up in Toronto, completed a master’s in epidemiology before earning his medical degree at Thomas Jefferson Medical College, and trained at Children’s Hospital of Los Angeles before founding Integrative Pediatrics. Dr. Warsh has published research in peer-reviewed journals on childhood injuries, obesity, and physical activity and has been featured in documentaries, summits, podcasts, and articles. Full show notes: bengreenfieldlife.com/hardplace Episode Sponsors: Ketone-IQ: Ketones are a uniquely powerful macronutrient that can cross the blood-brain barrier and increase brain energy and efficiency. With a daily dose of Ketone-IQ, you'll notice a radical boost in focus, endurance, and performance. Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG. LeelaQ: Not only do LeelaQ’s products neutralize EMFs, increase ATP production, optimize HRV, and improve blood flow, but they've been third-party proven to do so in placebo-controlled double-blind studies. Visit leelaq.com and use code BEN10 for 10% off. LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. Just Thrive: For a limited time, you can save 20% off a 90-day bottle of Just Thrive Probiotic and Just Calm at justthrivehealth.com/ben with promo code: BEN. That’s like getting a month for FREE—take control today with Just Thrive!See omnystudio.com/listener for privacy information.

2 Loka 202559min

Dietary Diversity or Carnivore: Which Fuels Better Health, Longevity, and Performance? Dr. Shawn Baker & Joel Greene Debate

Dietary Diversity or Carnivore: Which Fuels Better Health, Longevity, and Performance? Dr. Shawn Baker & Joel Greene Debate

In this episode we dive into a hotly debated topic: should you eat meat or not? Ben is joined by two powerhouse guests with decades of experience in nutrition and health—Dr. Shawn Baker, best-selling author of The Carnivore Diet and leading carnivore advocate, and Joel Greene, creator of The Immunity Code and champion of dietary diversity. In this spirited debate, Dr. Baker highlights the benefits of a strict carnivore approach—meat, eggs, some dairy, and minimal plant foods—not only for himself but also for patients managing chronic health issues. He explains why animal-based nutrition can be so effective, breaks down the science of ketosis and gut health, and responds to concerns about long-term effects of fiber-free diets. Meanwhile, Joel Greene makes the case for dietary variety, drawing from evolutionary biology, clinical research, and personal experience. He explores the synergies of combining animal and plant foods, the role of fiber in gut and immune health, and the ancestral rhythms of scarcity and feasting. Joel argues that even small amounts of diverse foods can offset downsides of strict elimination diets. Dr. Baker is a physician, athlete, and author known for his straightforward, meat-focused approach to nutrition and his background in strength sports. Joel is the creator of Veep Nutrition, a program targeting gut communities to improve health, used by major employers and featured on the Dr. Phil Show. Author of The Immunity Code, Joel has devoted 50 years to health and anti-aging, pioneering practices like MCTs in the ’80s, keto in the ’90s, and AMPK activation by 2009. At 55, he remains a 100% natural athlete. Full show notes: https://bengreenfieldlife.com/diversityorcarnivore/ Episode Sponsors: Unmatched: Outlier by Unmatched is the world's first pre-workout featuring Paraxanthine instead of caffeine, delivering sustained energy and focus without the crash, plus premium ingredients like Cognizin for cognitive enhancement and NO3-T for incredible muscle pumps. Try it at unmatchedsupps.com/bengreenfield with special bulk discounts: 15% off one, 20% off two, or 25% off three. Xtendlife: Future-proof your health with Xtendlife’s Total Balance—100+ bio-active ingredients in a gender-specific formula designed for longevity and complete daily support. Use code BEN15 at www.xtend-life.com/ben for 15% off sitewide, plus free shipping. IM8: Ditch the cabinet full of supplements—IM8 packs 92 powerhouse ingredients into one delicious scoop for all-day energy, gut health, and cellular support. Go to IM8Health.com and use code BEN for an exclusive gift—fuel your body the right way! LMNT: Everyone needs electrolytes, especially those on low-carb diets, who practice intermittent or extended fasting, are physically active, or sweat a lot. Go to DrinkLMNT.com/BenGreenfield to get a free sample pack with your purchase! Ketone-IQ: Ketone-IQ delivers science-backed performance fuel that increases power output by 19%, reduces fatigue by 10%, and naturally boosts EPO production for better oxygen delivery—trusted by elite athletes like Jon Jones and Olympic champions. Save 30% on your subscription plus get a free gift with your second shipment at Ketone.com/BENG.See omnystudio.com/listener for privacy information.

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Could This Be The World's Most POWERFUL Self-Quantification Device?! (& Is It Even *Safe* Or *Accurate*?) With Whoop's Will Ahmed

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18 Syys 20251h 6min

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13 Syys 20251h

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Could This “Bible Secret” Be The Cure For Cancer? The WISEST Meal In The World, Pork & Shellfish *Confusion* & Much More With Jordan Rubin

Could This “Bible Secret” Be The Cure For Cancer? The WISEST Meal In The World, Pork & Shellfish *Confusion* & Much More With Jordan Rubin

In this episode with repeat guest Jordan Rubin, you’ll uncover a holistic plan for building strength, health, and longevity from one of the world’s most recognized natural health experts. Jordan shares how his family tradition of reciting Psalm 91 and insights from his new book, The Biblio Diet, reveal timeless biblical wisdom for vibrant living. He also highlights his groundbreaking research on “healing leaves” from fruit trees—their potential to fight cancer, balance blood sugar, reduce inflammation, and support longevity—and how to turn them into a daily healing tea. Jordan Rubin is the founder of Garden of Life, Beyond Organic, and Ancient Nutrition, and the New York Times bestselling author of The Maker’s Diet and over 30 other titles, including The Biblio Diet. An eco-entrepreneur and global lecturer, he has shared his message of natural health worldwide, formulated nearly 1,000 bestselling supplements and functional foods, and operates Regenerative Organic Certified farms in Missouri and Tennessee. Full show notes: https://bengreenfieldlife.com/biblio Episode Sponsors: MASA Chips: Introducing the best guilt-free snack on the market: classic, seed oil free tortilla chips with only 3 natural ingredients. Go to masachips.com/greenfield and get 25% off your first order! Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Ketone-IQ: Ketone-IQ delivers science-backed performance fuel that increases power output by 19%, reduces fatigue by 10%, and naturally boosts EPO production for better oxygen delivery—trusted by elite athletes like Jon Jones and Olympic champions. Save 30% on your subscription plus get a free gift with your second shipment at Ketone.com/BENG. Fatty15: Fatty15 is on a mission to optimize your C15:0 levels and help you live healthier, longer. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/BEN and using code BEN at checkout. LVLUP Health: I trust and recommend LVLUP Health for your peptide needs as they third-party test every single batch of their peptides to ensure you’re getting exactly what you pay for and the results you’re after! Head over to lvluphealth.com/BGL and use code BEN15 for a special discount on their game-changing range of products. ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15.See omnystudio.com/listener for privacy information.

6 Syys 20251h 6min

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