#105 Does Exercise Stop Autophagy Because of mTOR Q&A

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:01 Are Too Many Supplements Bad for Organs 03:46 How to Clear Caffeine From the Body 07:00 When Do I Think Longevity Escape Velocity Will Begin 11:05 Bon Charge Sponsorship 11:49 How to Improve Sleep 14:45 What Biomarker I Want to Improve 19:04 mTOR and Longevity 24:05 How to Increase HRV Besides Exercise 26:25 Do I Have Cheat Meals 27:46 Astaxanthin and Testosterone 29:02 Taking 35 Grams of Glycine Per Day 31:09 Thoughts on Pterostilbene for Longevity 32:25 Essential Supplements for Vegans 34:20 Cancer Prevention 35:42 How to Improve Skin Elasticity 36:43 Does Calorie Restriction Decrease Performance Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF Join my next retreat at a longevity clinic: https://www.siimland.co/retreat

1 Syys 202440min

Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps 00:12 Alexis' background 03:00 What's available for regeneration currently 04:37 Alexis’ 3 step process for longevity medicine – Phase 1 09:30 The Longevity Leap Worksheet 10:09 Phase 2 - cleanup 12:35 Evidence for chelation therapies 13:58 Effects of senolytics 18:20 Phase 3 - regeneration 19:39 Exosomes and stem cells 28:09 Can exosomes extend lifespan 33:25 Peptides 39:08 Restoring melatonin levels 42:13 How many stem cells do you have 45:05 Why don't we live to 120 51:30 Can you remove plaque from arteries 56:10 What supplements Alexis takes 01:12:00 Diet and exercise 01:17:28 After the 3 phase plan Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

24 Elo 20241h 26min

Get my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/ Join our next retreat: https://www.siimland.co/retreat Timestamps: 00:40 Joe's 7th time at the clinic 01:25 Utilization of amino acids 09:00 What tests is Joe doing frequently 10:29 My new book The Longevity Leap 11:08 Joe on taking 150 supplements per day 22:02 Why Joe takes so many supplements 28:42 How genetics affects homocysteine 33:12 How Joe started coaching Liver King 36:47 Does everyone in the modern world need supplements 46:15 Genetics Joe Cohen YouTube channel: https://www.youtube.com/@thejoecohenshow

18 Elo 202448min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 01:00 Senescent Cells and Aging 09:18 Bon Charge Sponsorship 10:00 Immune System Aging 15:08 What Triggers Cell Senescence 18:50 How to Measure Cell Senescence 22:58 Senolytic Supplements and Drugs 35:50 mTOR, Rapamycin and Senescence 38:25 Aging and Autoimmunity 46:00 Recent Study on IL-11 and Life Extension 55:00 Mice Living Pathogen Free in Labs Matt Kaeberlein Optispan YouTube Channel: https://www.youtube.com/@optispan Get my new book The Longevity Leap: https://www.siimland.co/thelongevityleap

11 Elo 20241h

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:01 Recommended supplements for people in their 40s? 08:44 Three simplest ways to increase VO2 max 13:45 What will you do in your 30s that makes the biggest bang for your buck that is not exercise? 16:42 How to decrease stress levels? Any breath method? Supplements to deal with it? 19:57 I supplement with omega 3 high dose but I eat many nuts as well. Is my omega 3 wasted? 22:34 If you don’t have a sauna does a very hot shower bring the same or near benefits? 25:11 Does sex help increase longevity? 27:52 How did you do a fat loss phase? Lower carbs or fat? 30:42 I’d like to gain the weight healthy. Do you have any recommendations for the food, training? 34:16 Are you planning to start taking rapamycin? 36:24 When is your next retreat to India cause we’re coming 37:28 How did you lower your LDL? 38:54 Top 5 things that improved your sleep 42:42 What oil do you use to fry your sweet potato fries? 43:41 Thoughts on astaxanthin? Daily dose? 44:44 Do you take novos core supplement? Pre-order my new book: https://www.siimland.co/offers/Mo7aiaAh Join my next retreat at a longevity clinic: https://www.siimland.co/retreat

3 Elo 202447min

Pre-order my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/checkout Timestamps: 00:31 Life Expectancy Trends 03:08 Delay Chronic Diseases 06:26 Longest Living Man In History 10:21 Timeline of Chronic Diseases 12:23 Heart Disease and Neurodegeneration 14:45 Metabolic Syndrome 18:27 Slow Down Decline 22:17 Heart Rate and HRV 24:04 Muscle and Strength 25:35 Cognitive Decline Join the Biohacker Summit: https://biohackersummit.com/

28 Heinä 202428min

Pre-order my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/checkout

21 Heinä 20241h 5min

Pre-order my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/checkout Timestamps: 00:56 The Longevity Mix 01:28 Calcium Alpha-Ketoglutarate 03:58 Vitamin C 06:30 Creatine Monohydrate 07:32 Magnesium Citrate 09:18 Glucosamine Sulfate 10:15 Taurine 11:08 Glycine 13:17 Glutathione 14:14 Lysine 15:26 Ashwagandha 16:40 Theanine 17:26 Sodium Hyaluronate 18:42 Essential Softgels 19:05 Vitamin K1 21:00 Vitamin K2 22:20 Astaxanthin 23:35 Lutein and Zeaxanthin 24:25 Lycopene 25:06 Essential Capsules 25:41 Nicotinamide Riboside (NR) 26:40 Spermidine 27:37 Lithium 28:15 Rhodiola Rosea 28:30 CoQ10 29:17 NAC+Ginger+Curcumin 29:20 NAC 30:01 Curcumin 30:41 Ginger 31:34 Red Yeast Rice 32:10 Garlic 33:20 My Final Rating for Blueprint Supplements

14 Heinä 202434min