Podcast #395:  Aspirin for everyone!

Podcast #395: Aspirin for everyone!

Author: Aaron Lessen, MD

Educational Pearls:

  • In patients without indications for aspirin, three recent studies looked at prevention of several end points in the elderly
  • These showed no benefit in preventing cardiovascular events (stroke, MI, hear failure), disability, or death in elderly
  • These studies also demonstrated higher mortality and increased bleeding risk in patients who were taking aspirin without clear indications

Editor's note: the increased all cause mortality is intriguing - but attributed to an increase in cancer mortality. Unclear why but will be important to see if this trend is seen in other studies.

References:

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16. PubMed PMID: 30221596.

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1509-1518. doi: 10.1056/NEJMoa1805819. Epub 2018 Sep 16. PubMed PMID: 30221597.

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1519-1528. doi: 10.1056/NEJMoa1803955. Epub 2018 Sep 16. PubMed PMID: 30221595.

Summary by Travis Barlock, MS4 | Edited by Erik Verzemnieks, MD



Jaksot(1148)

Podcast 545: So You Quit Smoking… Now What?

Podcast 545: So You Quit Smoking… Now What?

Author: Aaron Lessen, MD Educational Pearls: New data shows within 5 years of smoking cessation, the risk of cardiovascular disease becomes half of those who continue to smoke After 10-15 years of c...

2 Maalis 20201min

UnfilterED #5: Dr. Lisa Zwerdlinger

UnfilterED #5: Dr. Lisa Zwerdlinger

Recorded remotely in the highest hospital in the world, Nick sits down to talk with Dr. Lisa Zwerdlinger, a small-town physician who's worn many different hats both in the hospital and her community. ...

26 Helmi 202033min

Podcast 544: C is for Sepsis

Podcast 544: C is for Sepsis

Author: Aaron Lessen, MD Educational Pearls: Previously, trials had shown promising evidence that vitamin C may improve mortality rates in patients with sepsis or septic shock. A 2017 retrospective...

25 Helmi 20202min

Podcast 543: Scoring Blunt Traumatic Aortic Injury

Podcast 543: Scoring Blunt Traumatic Aortic Injury

Author: Nick Tsipis, MD Educational Pearls: Aortic injury caused by blunt trauma is very rare Chest x-ray findings might include widening of the mediastinum Ligamentum arteriosum (remnant of the duct...

24 Helmi 20203min

Mental Health Monthly #2: Non-Epileptic Seizures (NES)

Mental Health Monthly #2: Non-Epileptic Seizures (NES)

Non Epileptic Seizures (NES) is perhaps one of the most misunderstood and overlooked disorders that emergency medicine professionals encounter. Dr. Randi Libbon & Dr. Laura Strom, both experts on NES,...

19 Helmi 202011min

Podcast 542: Nasogastric Tubes

Podcast 542: Nasogastric Tubes

Author: Don Stader, MD Educational Pearls: Nasogastric tubes (NGT) are very uncomfortable for all those involved but some simple tricks and tips may help: Topical lidocaine can be inserted into the n...

18 Helmi 20204min

Podcast 541: Needle Thoracostomy

Podcast 541: Needle Thoracostomy

Author: Aaron Lessen, MD Educational Pearls: Traditional technique of needle thoracostomy for tension penumothorax is along the 2nd intercostal space at the midclavicular line Inserting a large angio...

17 Helmi 20203min

On the Streets #1: The Art of the Handoff Report

On the Streets #1: The Art of the Handoff Report

EMM is proud to present the pilot episode of our new monthly series, "On the Streets". This will be an informative podcast for all of our listeners, but this one was designed specifically for our EMS ...

12 Helmi 202025min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
utelias-mieli
rss-poliisin-mieli
rss-duodecim-lehti
radio-antro
rss-sosiopodi
filocast-filosofian-perusteet
rss-ylistys-elaimille
rss-lihavuudesta-podcast
docemilia
mielipaivakirja
rss-tiedetta-vai-tarinaa
rss-tervetta-skeptisyytta